Results 121 to 130 of about 3,252 (154)

Cribriform plate microenvironment assembles a suppressive myeloid network during EAE-induced neuroinflammation. [PDF]

Elife
Laaker C, Hsu M, Madrid A, Port J, Vrba SM, Herbath M, Baenen C, Kumar M, Priyathilaka TT, Sandor M, Fabry Z.   +10 more
europepmc   +1 more source

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The meningeal lymphatic vasculature in neuroinflammation

The FASEB Journal, 2022
Abstract The lymphatic vasculature is a unidirectional network of lymphatic endothelial cells, whose main role is to maintain fluid homeostasis along with the absorption of dietary fat in the gastrointestinal organs and management and coordination of immune cell trafficking into lymph nodes during homeostasis and under inflammatory ...
Alexandra Olate‐Briones, Emilia Escalona, Celia Salazar, María José Herrada, Chaohong Liu, Andrés A. Herrada, Noelia Escobedo   +6 more
openaire   +2 more sources

Meningeal Lymphatic vasculature in health and disease

Current Opinion in Hematology, 2022
Purpose of review The recent (re)discovery of the meningeal lymphatic has brought a new player in brain neurophysiology. This review highlights the state of the current research on the meningeal lymphatic vasculature, from its specific physiology to its increasing implication in normal and pathological brain function.
Nisha, Busch, Liam, O'Reilly, Antoine, Louveau   +2 more
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Meningeal lymphatics, immunity and neuroinflammation

Current Opinion in Neurobiology, 2020
In the past five years, the surrounding of the brain, that is the meninges (singular meninx) have evolved from being a physical barrier that protects the brain parenchyma to becoming a central player for both the maintenance of normal brain function and the modulation of neurological disorders.
Natalie, Frederick, Antoine, Louveau
openaire   +2 more sources

Development and plasticity of meningeal lymphatic vessels [PDF]

Journal of Experimental Medicine, 2017
The recent discovery of meningeal lymphatic vessels (LVs) has raised interest in their possible involvement in neuropathological processes, yet little is known about their development or maintenance. We show here that meningeal LVs develop postnatally, appearing first around the foramina in the basal parts of the skull and spinal canal, sprouting along
Thomas Mathivet, Sinem Karaman, Mikko Airavaara   +2 more
exaly   +4 more sources

Meningeal lymphatics stem cognitive decline in craniosynostosis

Cell Stem Cell, 2023
Craniosynostosis is a congenital craniofacial disorder where premature fusion of cranial sutures causes elevated intracranial pressure and neurological deficits. In this issue of Cell Stem Cell, Ma et al. demonstrate that replenishing skull progenitor cells alleviates intracranial pressure elevations in craniosynostosis by restoring the meningeal ...
Taylor J, Stevenson, Kate, Hitpass Romero, Justin, Rustenhoven   +2 more
openaire   +2 more sources

The role of meningeal lymphatics in viral meningitis

The Journal of Immunology, 2017
Abstract Discovery of the meningeal lymphatic vessels in the brain meninges (coverings of the brain) led to the hypothesis that they carry macromolecules and immune cells from cerebrospinal fluid (CSF) to cervical lymph nodes (cLN). Our new findings suggest that the lymphatic system controls immune responses through guiding antigen ...
Jasmin Herz, Alexander Lupi, Dorian B McGavern, Jonathan Kipnis   +3 more
openaire   +1 more source

The meningeal lymphatics: regulators of Aβ immunotherapy?

Trends in Immunology, 2021
A new study by Da Mesquita et al. reports on how meningeal lymphatic modulation may influence amyloid-beta immunotherapy and microglial function in mouse models of Alzheimer's disease (AD). This research has broad implications for unraveling the role meningeal lymphatics may play in regulating immunity in the brain during AD pathology and treatment.
Collin Laaker, Zsuzsanna Fabry
openaire   +2 more sources

Lymphatic Capillaries in the Meninges of the Human Optic Nerve

Journal of Neuro-Ophthalmology, 1999
Although many anatomical studies of the orbit and the optic nerve have been performed, lymphatic capillaries in the dura of the human optic nerve have never been reported. This study was performed to determine whether or not lymphatic capillaries are present in the dura of the human optic nerve.This postmortem study was carried out in seven subjects ...
H E, Killer, H R, Laeng, P, Groscurth
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