Results 131 to 140 of about 3,252 (154)
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Regulation of meningeal lymphatic function by APOE
Alzheimer's & Dementia, 2023AbstractBackgroundThe meningeal layers form a unique interface between the central nervous and peripheral immune systems. The lymphatic vasculature that is present in the meningeal dura and drains cerebrospinal fluid (CSF) becomes dysregulated during aging and in models of neurodegenerative disorders such as Alzheimer’s disease (AD).
NIKOLETA DELIVANOGLOU +10 more
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Role of meningeal lymphatic vessels in brain homeostasis
Meningeal lymphatic vessels (MLVs) form an important bridging structure between the brain and periphery, which drains cerebral metabolites in cerebrospinal fluid (CSF) and brain antigens to deep cervical lymph nodes (dCLNs), to maintain brain homeostasis.
Qing Tian, Chao-Yuan Ye, Chao‐Yuan Ye
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Meningeal lymphatic network: The middleman of neuroinflammation
Clinical and Experimental Neuroimmunology, 2020AbstractThe central nervous system was long thought to be an immune‐privileged organ, notably because of its lack of conventional lymphatic drainage. Years of scientific observations and the recent (re)discovery of the meningeal lymphatic system has brought new insights into the relationship of the brain with the peripheral immune system.
Sarit Pal, Shilpa Rao, Antoine Louveau
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The role of the meningeal lymphatic in the brain clearing
Saratov Fall Meeting 2018: Computations and Data Analysis: from Nanoscale Tools to Brain Functions, 2019Here in ex vivo (confocal imaging) and in vivo (optical coherent tomography) experiments on adult mice, we clearly demonstrate that the meningeal lymphatic drainage is an important mechanism for the brain clearing that might be also pathway for the brain clearing from metabolites and waste products that requests further detailed studies.
Maria Klimova +9 more
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The Role of Meningeal Lymphatic Systems
The meningeal lymphatic system is a newly identified network of lymphatic vessels located within the meninges, the protective membranes enveloping the brain and spinal cord. This system is essential for clearing waste products, supporting immune responses, and ensuring the balance of brain functions.Gaiqing Wang +5 more
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Emerging Roles of Meningeal Lymphatic Vessels in Ischemic Stroke
Molecular NeurobiologyThis review highlights the emerging relevance of meningeal lymphatic vessels (MLVs) in the context of ischemic stroke, challenging the conventional view of a privileged immunological central nervous system. MLVs facilitate immunological surveillance by modulating the entry of peripheral immune cells into the meningeal compartment, a process not impeded
Richard Simon, Machado +7 more
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Effect Factors of Meningeal Lymphatics (MLVs)
The regulatory mechanism for meningeal lymphatics is not fully understood yet, but research is ongoing to uncover its functions and regulation. Several factors play a role in regulating these vessels, including: Circadian Rhythm: There is evidence suggesting that MLVs exhibit circadian rhythms in their function.Gaiqing Wang +5 more
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The glymphatic system and meningeal lymphatics of the brain: new understanding of brain clearance
Reviews in the Neurosciences, 2021Galina Valova +2 more
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Drainage of senescent astrocytes from brain via meningeal lymphatic routes
Brain, Behavior, and Immunity, 2022Ming Xiao, Fengfei Ding, Qian Li
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