Results 31 to 40 of about 123,166 (168)

Comprehensive Analysis of Differentially Expressed Profiles of mRNA N6-Methyladenosine in Colorectal Cancer

Frontiers in Cell and Developmental Biology, 2022
Aim: To comprehensively profile the landscape of the mRNA N6-methyladenosine (m6A) modification in human colorectal cancer (CRC).Methods: Methylated RNA immunoprecipitation sequencing (MeRIP-seq) was explored to compare the difference in mRNA N6 ...
Na Li, Qin Guo, Qiao Zhang, Bai-Jun Chen, Xiao-An Li, Yan Zhou   +5 more
doaj   +1 more source

Reduced YTHDF2 inhibits PD-L1 expression by stabilizing m6A-containing SPOP mRNA in colorectal cancer [PDF]

Cell Death and Disease
Colorectal cancer (CRC) is one of the most frequently diagnosed malignant tumors. However, clear evidence explaining the regulatory mechanisms of programmed death ligand 1 (PD-L1) in CRC has been limited.
Xian Xu, Hao Chen, Rongjie Zhao, Jiansheng Xie, Hao Liu, Binbin Xie, Jun Lou, Haidong Wang, Xinkai Wu, Weidong Han, Hongming Pan, Jiaying Shen   +11 more
doaj   +2 more sources

Comprehensive Analysis of N6-Methyladenosine Methylation in Transverse Aortic Constriction-Induced Cardiac Fibrosis Based on MeRIP-Seq Analysis. [PDF]

Biomedicines
Background: The function and mechanism of N6-methyladenosine (m6A) methylation in pressure-overload cardiac fibrosis remains limited and unclear. This study aims to analyze and predict m6A modifications present in mouse hearts because of transverse aortic constriction (TAC).
Liu S, Zhao P, He Y, Wang J, Song B, Yu C.   +5 more
europepmc   +4 more sources

Comprehensive analysis of transcriptome-wide m6A methylome in the lung tissues of mice with acute particulate matter exposure

Ecotoxicology and Environmental Safety, 2022
Particulate matter (PM) exposure is identified as a critical risk factor for chronic airway diseases, but the biological mechanism of PM-induced lung damage was not fully elucidated.
Juan Song, Yingying Zeng, Mengchan Zhu, Guiping Zhu, Cuicui Chen, Meiling Jin, Jian Wang, Yuanlin Song   +7 more
doaj   +1 more source

REPIC: a database for exploring the N 6-methyladenosine methylome

Genome Biology, 2020
The REPIC (RNA E PItranscriptome Collection) database records about 10 million peaks called from publicly available m6A-seq and MeRIP-seq data using our unified pipeline. These data were collected from 672 samples of 49 studies, covering 61 cell lines or
Shun Liu, Allen Zhu, Chuan He, Mengjie Chen   +3 more
doaj   +1 more source

N6‐methyladenosine reader YTHDF3 regulates melanoma metastasis via its ‘executor' LOXL3

Clinical and Translational Medicine, 2022
Background A number of studies have demonstrated that N6‐methyladenosine (m6A) plays a vital role in the pathological process of various tumours. Recently, it was found that m6A writers or erasers affect the tumourigenesis of melanoma.
Hao‐ze Shi, Jing‐shu Xiong, Lu Gan, Ying Zhang, Cong‐cong Zhang, Ying‐qi Kong, Qiu‐ju Miao, Cui‐cui Tian, Rong Li, Jin‐quan Liu, Er‐jia Zhang, Wen‐bo Bu, Yan Wang, Xian‐feng Cheng, Jian‐fang Sun, Hao Chen   +15 more
doaj   +1 more source

Role of N6-methyladenosine methylation in transverse aortic constriction-induced cardiac fibrosis: insights from MeRIP-seq analysis. [PDF]

Mol Biol Rep
Abstract This study aimed to investigate the role and potential mechanisms of N6-methyladenosine (m6A) methylation in a mouse model of transverse aortic constriction (TAC)-induced cardiac fibrosis using MeRIP-seq. A TAC-induced cardiac fibrosis mouse model was established, and cardiac function and structural parameters were assessed ...
Liu S, Liu H, Bai Q, Wei Z, Zhao P, Chen H, Song B, Yu C.   +7 more
europepmc   +4 more sources

merip-seq

, 2023
merip-seq 
Shuyi Mi (15058927)
core   +1 more source

MeRIP-seq result

, 2022
Poplar 84K seedlings were treated with 100 mM NaCl for 48h.
Ye Zhao (11948567)
core   +1 more source

Comprehensive Transcriptomic Profiling of m6A Modification in Age-Related Hearing Loss

Biomolecules, 2023
Age-related hearing loss (ARHL), also known as presbycusis, is one of the most common neurodegenerative disorders in elderly individuals and has a prevalence of approximately 70–80% among individuals aged 65 and older.
Menglong Feng, Xiaoqing Zhou, Yaqin Hu, Juhong Zhang, Ting Yang, Zhiji Chen, Wei Yuan   +6 more
doaj   +1 more source