Results 1 to 10 of about 23,516 (117)
Crosstalk between m6A modification and alternative splicing during cancer progression
Clinical and Translational Medicine, 2023 Background N6‐methyladenosine (m6A), the most prevalent internal mRNA modification in eukaryotes, is added by m6A methyltransferases, removed by m6A demethylases and recognised by m6A‐binding proteins.
Fu-Chun Huo, Dong-Sheng Pei
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The Role of m6A Ribonucleic Acid Modification in the Occurrence of Atherosclerosis
Frontiers in Genetics, 2021 The N6-methyladenosine (m6A) modification is the most abundant epitranscriptomic modification in eukaryotic messenger RNA (mRNA). The m6A modification process is jointly regulated by various enzymes and proteins, such as methyltransferases, demethylases ...
Xiaodong Cui +2 more
exaly +3 more sources
Link Between m6A Modification and Cancers
Frontiers in Bioengineering and Biotechnology, 2018 N6-methyladenosine (m6A) epitranscriptional modification has recently gained much attention. Through the development of m6A sequencing, the molecular mechanism and importance of m6A have been revealed.
Hui-Lung Sun +2 more
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Genes and Diseases, 2023 N6-methyladenosine (m6A) RNA modification is widely perceived as the most abundant and common modification in transcripts. This modification is dynamically regulated by specific m6A “writers”, “erasers” and “readers” and is reportedly involved in the ...
Lili Feng +5 more
doaj +1 more source
Frontiers in Genetics, 2021 Objective: N6-methyladenosine (m6A) modification may modulate various biological processes. Nonetheless, clinical implications of m6A modification in pancreatic cancer are undefined.
Kun Fang +6 more
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Pseudorabies virus exploits N6-methyladenosine modification to promote viral replication
Frontiers in Microbiology, 2023 IntroductionPseudorabies virus (PRV) is the pathogenic virus of porcine pseudorabies (PR), belonging to the Herpesviridae family. PRV has a wide range of hosts and in recent years has also been reported to infect humans.
Pei-Lun Yu +21 more
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Frontiers in Oncology, 2022 As the most common post-transcriptional RNA modification, m6A methylation extensively regulates the structure and function of RNA. The dynamic and reversible modification of m6A is coordinated by m6A writers and erasers. m6A reader proteins recognize m6A
Xun Chen +11 more
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Research progress of m6A methylation in prostate cancer
Asian Journal of Andrology, 2023 N6-methyladenosine (m6A) is a ubiquitous RNA modification in mammals. This modification is “written” by methyltransferases and then “read” by m6A-binding proteins, followed by a series of regulation, such as alternative splicing, translation, RNA ...
Shou-Yi Zhang, Yu Zeng
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Frontiers in Oncology, 2021 BackgroundStudies have shown that N6-methyl adenosine (m6A) plays an important role in cancer progression; however, the underlying mechanism of m6A modification in tumor microenvironment (TME) cell infiltration of bladder cancer remains unclear.
Huili Zhu +6 more
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Frontiers in Oncology, 2023 N6-methyladenosine (m6A) is the most pervasive RNA modification in eukaryotic cells. The dynamic and reversible m6A modification of RNA plays a critical role in the occurrence and progression of tumors by regulating RNA metabolism, including ...
Xiaohan Jiang +7 more
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