Results 41 to 50 of about 1,875,792 (320)
Journal of Translational Medicine, 2023 Background Endometriosis (EMs), the ectopic planting of functional endometrium outside of the uterus, is a leading cause of infertility and pelvic pain.
Xiaotong Wang +10 more
semanticscholar +1 more source
The Potential Roles of RNA N6-Methyladenosine in Urological Tumors
Frontiers in Cell and Developmental Biology, 2020 N6-methyladenosine (m6A) is regarded as the most abundant, prevalent and conserved internal mRNA modification in mammalian cells. M6A can be catalyzed by m6A methyltransferases METTL3, METTL14 and WTAP (writers), reverted by demethylases ALKBH5 and FTO ...
Yang Li +5 more
doaj +1 more source
Scientific Reports, 2023 N 6-methyladenosine (m6A) is a form of posttranscriptional modification that plays important roles in cancer including oral squamous cell carcinoma (OSCC).
Lu Pan +6 more
doaj +1 more source
METTL3 regulates WTAP protein homeostasis [PDF]
, 2018 The Wilms tumor 1 (WT1)-associated protein (WTAP) is upregulated in many tumors, including, acute myeloid leukemia (AML), where it plays an oncogenic role by interacting with different proteins involved in RNA processing and cell proliferation.
Capuano, Ernestina +8 more
core +2 more sources
Frontiers in Immunology, 2022 BackgroundFew studies have been reported the potential role of N6-methyladenosine (m6A) modification in osteoarthritis (OA). We investigated the patterns of m6A modification in the immune microenvironment of OA.MethodsWe evaluated the m6A modification ...
Yulong Ouyang +9 more
doaj +1 more source
Clinical and Translational Medicine, 2023 Background Circular RNA (circRNA) and N6‐methyladenosine (m6A) play a critical role in tumour occurrence and development, including colorectal cancer (CRC). However, little is known about the interaction between circRNA and m6A in the radiosensitivity of
Yingjie Shao +11 more
semanticscholar +1 more source
The Emerging Role of m6A Modification in Endocrine Cancer
Cancers, 2023 With the development of RNA modification research, N6-methyladenosine (m6A) is regarded as one of the most important internal epigenetic modifications of eukaryotic mRNA. It is also regulated by methylase, demethylase, and protein preferentially recognizing the m6A modification.
Ji, Xiaoyu +3 more
openaire +2 more sources
Modulation of internuclear communication in multinuclear Ruthenium(II) polypyridyl complexes [PDF]
, 2003 The syntheses and characterisation of a series of mononuclear and dinuclear ruthenium polypyridyl complexes based on the bridging ligands 1,3-bis-[5-(2-pyridyl)-1H-1,2,4-triazol-3-yl]benzene, 1,4-bis-[5-(2-pyridyl)-1H-1,2,4-triazol-3-yl]benzene, 2,5-bis-[
Adrian Guckian +4 more
core +2 more sources
Clinical and Translational Medicine, 2023 Background N 6‐methyladenosine (m6A) is of great importance in renal physiology and disease progression, but its function and mechanism in renal fibrosis remain to be comprehensively and extensively explored.
W. Ni +12 more
semanticscholar +1 more source
Roles and therapeutic implications of m6A modification in cancer immunotherapy
Frontiers in Immunology, 2023 Recent studies have demonstrated that N6-methyladenosine (m6A), the most abundant, dynamic, and reversible epigenetic RNA modification in eukaryotes, is regulated by a series of enzymes, including methyltransferases (writers), demethylases (erasers), and
Juan Pan +3 more
semanticscholar +1 more source