Results 31 to 40 of about 18,495 (202)
Merkel cell carcinoma arising from postoperative scar: An unusual presentation
Turkderm Turkish Archives of Dermatology and Venereology, 2021 Merkel cell carcinoma (MCC) is an aggressive and uncommon primary cutaneous neuroendocrine cancer. With unknown pathogenesis, immunosuppression, ultraviolet radiation, Merkel cell polyomavirus, and arsenic exposure are the risk factors.
Mualla Polat +4 more
doaj +1 more source
World Journal of Surgical Oncology, 2006 AbstractBackgroundMerkel cell carcinoma (MCC) is an unusual primary neuroendocrine carcinoma of the skin. MCC is a fatal disease, and patients have a poor chance of survival. Moreover, MCC lacks distinguishing clinical features, and thus by the time the diagnosis is made, the tumour usually have metastasized.
openaire +3 more sources
Kidney metastasis in a case of Merkel cell carcinoma
Urology Case Reports, 2021 Merkel cell carcinoma is a rare neuroendocrine skin tumor with a poor prognosis. Metastasis is frequent and is seen in the first few years after diagnosis.
Abdessamade Motaouakil +5 more
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PLoS ONE, 2019 Engineered skin substitutes (ESS), prepared using primary human fibroblasts and keratinocytes with a biopolymer scaffold, were shown to provide stable closure of excised burns, but relatively little is known about innervation of ESS after grafting.
Jennifer M Hahn +5 more
doaj +1 more source
A Cascade of Wnt, Eda, and Shh Signaling Is Essential for Touch Dome Merkel Cell Development.
PLoS Genetics, 2016 The Sonic hedgehog (Shh) signaling pathway regulates developmental, homeostatic, and repair processes throughout the body. In the skin, touch domes develop in tandem with primary hair follicles and contain sensory Merkel cells.
Ying Xiao +8 more
doaj +1 more source
Hematology/Oncology Clinics of North AmericaMerkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine skin cancer that is highly radiosensitive and immunogenic. Immunotherapy is the primary treatment of advanced disease, and immune checkpoint inhibitors show promise as neoadjuvant or adjuvant therapy in patients with high-risk resectable MCC.
Strong, Jennifer +2 more
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JAAD International, 2022 Background: Merkel cell carcinoma of lower limb and hip skin is a rare skin tumor that has a high recurrence rate. Objective: To assess epidemiology and survival outcomes of the lower limb and hip Merkel cell carcinoma, which are less addressed in the ...
Matteo Scampa, MS +4 more
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Journal of Investigative Dermatology, 1973 The Merkel cell is a distinctive cell normally found in the epidermis of mammals. It possesses a folded nucleus; a clear, organelle-rich cytoplasm with peripheral protrusions among the epithelial cells; and a few desmosomal attachments to adjacent cells.
Winkelmann, R.K., Breathnach, A.S.
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Advanced Healthcare Materials, EarlyView.Models of the human skin must combine the relevant biological contents and suitable biomaterials with the correct spatial organization. Performing compound screening on such in vitro models also requires fast and reproducible production methods of the models.
Elisa Lenzi +7 more
wiley +1 more source
Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application
Advanced Materials, EarlyView.This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong +12 more
wiley +1 more source