Results 11 to 20 of about 63,064 (231)
Bezmiâlem Science, 2023 Merkel cell carcinoma (MCC) is a rare tumor that arises from mechanoreceptor Merkel cells. Ultraviolet exposure, immunosuppression and Merkel cell polyoma virus play a significant role in tumor pathogenesis. Although it typically presents as an initially
Selma SÖNMEZ ERGÜN +5 more
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Merkel Cell Polyomavirus and Merkel Cell Carcinoma, France
Emerging Infectious Diseases, 2008 To the Editor: Merkel cell carcinoma (MCC) is a primary cutaneous neuroendocrine tumor. This aggressive skin cancer is uncommon but increasing in frequency. During 1986–2001, incidence rate tripled; average annual increase was 8% (1). MCC shares epidemiologic features with Kaposi sarcoma, a malignant tumor associated with human herpesvirus 8 infection (
Vincent Foulongne +5 more
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Skin Health and Disease, 2021 Abstract Merkel cell carcinoma (MCC) is a rare neuroendocrine carcinoma. The cellular origin of MCC may include Merkel cell precursors. The incidence of MCC has increased significantly however trends may have been confounded by evolving diagnostic criteria.
K. Mistry +4 more
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Merkel Cell Polyomavirus and Merkel Cell Carcinoma [PDF]
Cancers, 2020 Viruses are the cause of approximately 15% of all human cancers. Both RNA and DNA human tumor viruses have been identified, with Merkel cell polyomavirus being the most recent one to be linked to cancer. This virus is associated with about 80% of Merkel cell carcinomas, a rare, but aggressive cutaneous malignancy.
Valeria Pietropaolo +2 more
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Merkel Cell Polyomavirus Strains in Patients with Merkel Cell Carcinoma
Emerging Infectious Diseases, 2009 We investigated whether Merkel cell carcinoma (MCC) patients in France carry Merkel cell polyomavirus (MCPyV) and then identified strain variations. All frozen MCC specimens and 45% of formalin-fixed and paraffin-embedded specimens, but none of the non ...
Antoine Touzé +10 more
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Surgical Pathology Clinics, 2017 Merkel cell carcinoma (MCC) encompasses neuroendocrine carcinomas primary to skin and occurs most commonly in association with clonally integrated Merkel cell polyomavirus with related retinoblastoma protein sequestration or in association with UV radiation-induced alterations involving the TP53 gene and mutations, heterozygous deletion, and ...
Becker, Jürgen +6 more
+11 more sources
New England Journal of Medicine, 2019 In XXI century Merkel cell carcinoma (MCC) is a still very rare form of the skin cancer with an aggressive behavior. We present a case of 77-year-old female patient with a tumor with bluish skin, approx. 2 cm diameter, hard texture palpation of the right zygomatic area of the face. There were no enlarged lymph nodes in the head or neck.
Pedro J. Gomez-Arias +1 more
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Merkel cell polyomavirus infection and Merkel cell carcinoma [PDF]
Current Opinion in Virology, 2016 Merkel cell polyomavirus is the only polyomavirus discovered to date that is associated with a human cancer. MCPyV infection is highly prevalent in the general population. Nearly all healthy adults asymptomatically shed MCPyV from their skin. However, in elderly and immunosuppressed individuals, the infection can lead to a lethal form of skin cancer ...
Wei, Liu, Margo, MacDonald, Jianxin, You
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Journal of the National Comprehensive Cancer Network, 2009 (Staging for Merkel Cell of the eyelid [C44.1] is not included in this chapter – see Chap. 48, “Carcinoma of the Eyelid” in the AJCC Cancer Staging Manual)
Stanley J, Miller +25 more
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Dual innervation of neonatal Merkel cells in mouse touch domes. [PDF]
PLoS ONE, 2014 Merkel cell-neurite complexes are specialized mechanosensory end organs that mediate discriminative touch sensation. It is well established that type I slowly adapting (SAI) mechanoreceptors, which express neural filament heavy chain (NFH), innervate ...
Jingwen Niu, Anna Vysochan, Wenqin Luo
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