Results 81 to 90 of about 2,271 (197)

Endophytic Fungi Natural Factories of Novel Bioactive Compounds

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
This review provides a systematic analysis of 242 natural products isolated from 42 genera of endophytic fungi, highlighting their remarkable structural diversity and broad spectrum of biological activities . ABSTRACT Endophytic fungi represent a prolific and chemically diverse source of novel specialized metabolites with significant pharmacological ...
Dilmurod Murodullayev, Jakhongir Movlanov, Liu Wei, Wei Liu, Maksud Isokov, Santosh Kumar Bose, Fazliddin Kobilov, Zamira Djumayeva, Buston Islamov, Jamila Sherkulova, Zafar Matyakubov, Muniskhon Meylieva, Munisa Ergasheva, Diyor Abduraxmanov, Guozheng Huang, Hongchen Jiang, Kakhramon Davranov, Guohui Pan, Nigora Rustamova   +18 more
wiley   +1 more source

Diversification of the Avarane Skeleton Toward Spiroetherone A

ChemistryEurope, Volume 4, Issue 9, September 2026.
Molecular complexity and diversity were generated from the avarone skeleton, leading, among other transformations, to an oxaspiro[4.5]dienone via Wagner–Meerwein rearrangements, a popolohuanone E‐like dibenzofuran via a (3+2) dimerization, and a pentacyclic imidate via a tandem PIDA‐mediated alkene–phenol cyclization/Ritter reaction.
Guillaume Schoenn, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent   +3 more
wiley   +1 more source

Mushrooms of the Genus Ganoderma Used to Treat Diabetes and Insulin Resistance

Molecules, 2019
Pharmacotherapy using natural substances can be currently regarded as a very promising future alternative to conventional therapy of diabetes mellitus, especially in the case of chronic disease when the body is no longer able to produce adequate insulin ...
Katarzyna Wińska, Wanda Mączka, Klaudia Gabryelska, Małgorzata Grabarczyk   +3 more
doaj   +1 more source

Alcoholic extracts of Russian sage (Salvia yangii) contain bioactive terpenoids with inhibitory activity against grapevine downy mildew (Plasmopara viticola)

Pest Management Science, Volume 82, Issue 9, Page 8159-8170, September 2026.
Alcoholic extracts from flowers, leaves, and shoots of Russian sage decreased downy mildew severity on grapevine leaf disks. Fractionation followed by metabolomic analysis revealed putative terpenoids as the main components of the active fractions. Specifically, 7‐methylrosmanol, 12‐O‐methylcarnosic acid, carnosic acid, and carnosol were identified as ...
Anna Smaldone, Oscar Giovannini, Martina Magni, Michael Oberhuber, Peter Robatscher, Michele Perazzolli   +5 more
wiley   +1 more source

Syntheses of unnatural meroterpenoids and evaluation of their anticancer potential [PDF]

, 2018
Supervisor: Chandan K. JanaThe contents of this thesis entitled “Syntheses of Unnatural Meroterpenoids and Evaluation of Their Anticancer Potential” have been divided into seven chapters.
Haque, Md Ashraful
core   +1 more source

Model studies on the synthesis of the natural meroterpenoid cordiaquinone A

Ecletica Quimica, 2001
Two main strategies for the synthesis of the natural meroterpenoid cordiaquinone A (1) - isolated of the roots of Cordia corymbosa G. Don (Boraginaceae) - were tested on model compounds. Whereas all attempts of alkylation of e-caprolactone (10) were unsuccessful, the coupling of epoxycitronellol (17) with an appropriate organocuprate proceeded in the ...
BATALINI, Claudemir, BIEBER, Lothar Wilhelm   +1 more
openaire   +4 more sources

A MassQL‐Based Framework for Rule‐Guided MS/MS Class‐Level Retrieval and Analog Discovery of Cannabinoids

Rapid Communications in Mass Spectrometry, Volume 40, Issue 16, 30 August 2026.
ABSTRACT Rationale Cannabinoids comprise a chemically diverse group of meroterpenoids whose extensive isomerism, variable side‐chain length, and frequent oxidative or rearranged derivatives lead to strongly overlapping yet characteristic MS/MS fragmentation patterns. In untargeted LC–MS/MS datasets, this combination of structural diversity and spectral
Julia Maia Galvão de Queiroz, Fernanda Oliveira Chagas, Valdir Florêncio Veiga‐Júnior, Monica Costa Padilha, Ricardo M. Borges   +4 more
wiley   +1 more source

Meroterpenoids from the Brown Alga Cystoseira usneoides as Potential Anti-Inflammatory and Lung Anticancer Agents

Marine Drugs, 2020
The anti-inflammatory and anticancer properties of eight meroterpenoids isolated from the brown seaweed Cystoseira usneoides have been evaluated. The algal meroterpenoids (AMTs) 1–8 were tested for their inhibitory effects on the production of the pro ...
Hanaa Zbakh, Eva Zubía, Carolina de los Reyes, José M. Calderón-Montaño, Miguel López-Lázaro, Virginia Motilva   +5 more
doaj   +1 more source

Anisotropic NMR as a Crucial Tool for Differentiation of Epimers With High Conformational Flexibility

Angewandte Chemie, Volume 138, Issue 30, 20 July 2026.
Epimer discrimination remains challenging due to subtle NMR differences. Here, we propose a methodology based on 13C‐RCSA and RDC anisotropic parameters, enabling the assignment of two flexible tetraprenyltoluquinol epimers (1a and 1b) with remote stereoclusters.
Juan Carlos C. Fuentes‐Monteverde, Abel M. Forero, Nilamoni Nath, Antonio Hernández Daranas, Carlos Jiménez, Jaime Rodríguez, Christian Griesinger   +6 more
wiley   +1 more source

Novel metabolite madeirone and neomarinone extracted from Streptomyces aculeoletus as marine antibiofilm and antifouling agents

Frontiers in Chemistry
Introduction: Biofouling poses a significant economic threat to various marine industries, leading to financial losses that can reach billions of euros annually.
Julian L. Wissner, Julian L. Wissner, Julian L. Wissner, Joana R. Almeida, Inês R. Grilo, Inês R. Grilo, Jhenifer F. Oliveira, Jhenifer F. Oliveira, Carolina Brízida, Carolina Brízida, Wendy Escobedo-Hinojosa, Wendy Escobedo-Hinojosa, Wendy Escobedo-Hinojosa, Panayiota Pissaridou, Marlen I. Vasquez, Isabel Cunha, Rita G. Sobral, Rita G. Sobral, Vítor Vasconcelos, Vítor Vasconcelos, Susana P. Gaudêncio, Susana P. Gaudêncio   +21 more
doaj   +1 more source