Results 1 to 10 of about 9,393 (236)

Oxidation of Mesalamine under Phenoloxidase- or Peroxidase-like Enzyme Catalysis

open access: yesMolecules, 2023
Mesalamine, also called 5-ASA (5-aminosalicylic acid), is a largely used anti-inflammatory agent and is a main choice to treat Ulcerative Colitis. This report is aimed to investigate enzymatic processes involved in the oxidation of mesalamine to better ...
Rimaz El Zein   +4 more
doaj   +2 more sources

Mesalamine-Induced Myocarditis [PDF]

open access: yesCardiology Research and Practice, 2010
Nowadays mesalamine is a common treatment for Crohn's disease and hypersensitive reactions to this product have been reported. Yet there is limited information concerning mesalamine-induced myocarditis and its mechanism is not known.
Olivier Merceron   +6 more
doaj   +3 more sources

Development of Novel pH-Sensitive Eudragit Coated Beads Containing Curcumin-Mesalamine Combination for Colon-Specific Drug Delivery

open access: yesGels, 2023
This research aims to develop a drug delivery system that effectively treats colitis while administering curcumin/mesalamine by coating alginate/chitosan beads with Eudragit® S-100 to target the colon. Beads were tested to determine their physicochemical
Eman J. Heikal   +8 more
doaj   +2 more sources

Gut Microbiota and Related Metabolites Were Disturbed in Ulcerative Colitis and Partly Restored After Mesalamine Treatment

open access: yesFrontiers in Pharmacology, 2021
Mesalamine has been well used in the improvement of ulcerative colitis (UC) in clinics, however, the underlying mechanisms were not well illustrated. To explore its efficacy from the perspective of gut microbiota and related metabolites, we employed 16S ...
Liang Dai   +8 more
doaj   +2 more sources

Exacerbation of Bloody Diarrhea as a Side Effect of Mesalamine Treatment of Active Ulcerative Colitis [PDF]

open access: goldCase Reports in Gastroenterology, 2011
Mesalamine has been used as the first-line therapy for the treatment of ulcerative colitis (UC) because of its efficacy and fewer side effects. However, earlier study showed that mesalamine occasionally causes diarrhea.
Yuichi Shimodate   +5 more
doaj   +2 more sources

Effects of Mesalamine Combined with Live Combined Bifidobacterium, Lactobacillus and Enterococcus Capsules on Intestinal Mucosa Barrier Function and Intestinal Microbiota in Mildly Active Crohn’s Disease Patients

open access: yesJournal of Investigative Surgery, 2023
Objective: This study is aimed at investigating the impact of mesalamine combined with Live combined Bifidobacterium, Lactobacillus and Enterococcus capsules on intestinal mucosa barrier function and intestinal microbiota in mildly active Crohn’s disease
Meiqin Shen   +3 more
doaj   +2 more sources

Recent advances in mesalamine colonic delivery systems

open access: yesFuture Journal of Pharmaceutical Sciences, 2020
Background Increased attention has been focused on the continuous development and improvement of mesalamine colonic specific delivery systems, for the effective treatment of inflammatory bowel diseases; thus enhancing therapeutic efficacy and reducing ...
Mohammad F. Bayan, Rana F. Bayan
doaj   +2 more sources

Mesalamine induced eosinophilic pneumonia

open access: yesRespiratory Medicine Case Reports, 2017
We present the case of a twenty two year old Caucasian male with ulcerative colitis on mesalamine who presented with dry cough, fever, malaise and dyspnea on exertion.
Ankit Gupta, MD, MS   +1 more
doaj   +3 more sources

A Comparison of Budesonide and Mesalamine for Active Crohn's Disease [PDF]

open access: bronzeNew England Journal of Medicine, 1998
Crohn's disease is often treated with glucocorticoids or mesalamine. We compared the efficacy and safety of controlled-ileal-release budesonide capsules and slow-release mesalamine tablets in patients with active Crohn's disease affecting the ileum, the ascending colon, or both.In a double-blind, multicenter trial, we enrolled 182 patients with scores ...
Antoine Cortot   +8 more
openaire   +4 more sources

Update on the role of modified release mesalamine in the management of ulcerative colitis and Crohn’s disease

open access: goldClinical and Experimental Gastroenterology, 2009
Glen A Doherty, Mark A PeppercornCenter for Inflammatory Bowel Disease, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston MA, USAAbstract: 5-aminosalicyclates (5-ASA) remain a key first-line therapy for patients with ulcerative ...
Glen A Doherty, Mark A Peppercorn
doaj   +3 more sources

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