Results 11 to 20 of about 9,412 (255)

Inflammatory bowel disease type influences development of elevated liver enzymes

JGH Open, Volume 6, Issue 12, Page 846-853, December 2022., 2022
We evaluated the incidence, predictors, and outcomes associated with elevated liver enzymes (ELE) in a diverse and vulnerable inflammatory bowel disease cohort. In multivariate Cox regression, ulcerative colitis (vs Crohn's disease) had a 34% lower risk of developing new ELE during follow‐up (hazard ratio 0.66, 95% confidence interval: 0.46–0.95, P = 0.
Yao‐Wen Cheng, Richard McLean, Justin L Sewell, Chiung‐Yu Huang, Mandana Khalili   +4 more
wiley   +1 more source

Drug-Induced Intersticial Nephritis. Clinical Case

Acta Medica Lituanica, 2021
5-Aminosalicylic acid (5-ASA) preparations are widely used in the treatment of inflammatory bowel diseases. The most commonly used medicine is mesalamine. Overall, it is a very safe drug with few side effects.
Paulina Tekoriutė, Monika Matuliauskaitė, Laimas Virginijus Jonaitis   +2 more
doaj   +1 more source

Risk of Hemolytic Anemia in IBD Patients with Glucose-6-Phosphate Dehydrogenase Deficiency Treated with Mesalamine: Results of a Retrospective-Prospective and Ex Vivo Study

Journal of Clinical Medicine, 2023
Background: Mesalamine is one of the most-used drugs in inflammatory bowel disease (IBD), especially ulcerative colitis. Regulatory agencies have listed mesalamine as an unsafe drug in subjects with glucose-6-phosphate dehydrogenase (G6PD) deficiency ...
M. Dore, Giulia Tomassini, C. Rocchi, M. Bulajic, M. Carta, A. Errigo, Alberto Dimaggio, Federica Padedda, G. Pes   +8 more
semanticscholar   +1 more source

Recurrent Pericarditis: A Rare Adverse Effect of Mesalamine

Cureus, 2023
Inflammation of the myocardium (myocarditis), pericardium (pericarditis), or both (myopericarditis) is a rare but potentially lethal side effect of mesalamine, a drug widely used in the treatment of inflammatory bowel disease (IBD).
Pratul Karki, Ariya Kunwar, N. Sharma, Megha Dogra   +3 more
semanticscholar   +1 more source

Recyclable mesalamine-functionalized magnetic nanoparticles (mesalamine/GPTMS@SiO2@Fe3O4) for tandem Knoevenagel–Michael cyclocondensation: grinding technique for the synthesis of biologically active 2-amino-4H-benzo[b]pyran derivatives

RSC Advances, 2023
In the present study, mesalamine-functionalized on magnetic nanoparticles (mesalamine/GPTMS@SiO2@Fe3O4) is fabricated as an efficient and magnetically recoverable nanocatalyst.
Mahdiyeh Partovi, Sobhan Rezayati, Ali Ramazani, Yavar Ahmadi, Hooman Taherkhani   +4 more
semanticscholar   +1 more source

Genetic variants in cellular transport do not affect mesalamine response in ulcerative colitis. [PDF]

PLoS ONE, 2018
Mesalamine is commonly used to treat ulcerative colitis (UC). Although mesalamine acts topically, in vitro data suggest that intracellular transport is required for its beneficial effect.
Christopher J Moran, Hailiang Huang, Manuel Rivas, Jess L Kaplan, Mark J Daly, Harland S Winter   +5 more
doaj   +1 more source

Pregnancy outcomes in inflammatory bowel disease: Data from a large cohort survey

Journal of Digestive Diseases, Volume 23, Issue 8-9, Page 473-481, August‐September 2022., 2022
A survey was carried out to investigate the outcomes of pregnancy in women with inflammatory bowel disease (IBD) compared with a non‐IBD control group. The risk of intrauterine growth restriction (IUGR), poor blood pressure control, and cesarean section were higher in IBD women.
Tommaso Innocenti, Jenny Roselli, Alice Taylor, Gabriele Dragoni, Erica Nicola Lynch, Claudia Campani, Matteo Gottin, Siro Bagnoli, Giuseppe Macrì, Francesca Rogai, Stefano Milani, Andrea Galli, Monica Milla   +12 more
wiley   +1 more source

A Hydrogen-Sulfide Derivative of Mesalamine Reduces Severity of Intestinal and Lung Injury in Necrotizing Enterocolitis via Endothelial Nitric Oxide Synthase.

American Journal of Physiology. Regulatory Integrative and Comparative Physiology, 2022
PURPOSE Necrotizing enterocolitis (NEC) remains a devastating disease that affects preterm infants. Hydrogen sulfide (H2S) donors have been shown to reduce the severity of NEC, but the optimal compound has yet to be identified.
B. Hosfield, Chelsea E. Hunter, Hongge Li, N. Drucker, Anthony R. Pecoraro, K. Manohar, W. Shelley, T. Markel   +7 more
semanticscholar   +1 more source

Mesalamine Associated Bradycardia [PDF]

Cureus, 2018
A 38-year-old female presented with an acute flare of ulcerative colitis. She was started on prednisone and mesalamine. Within 24 hours of initiating mesalamine, she developed sinus bradycardia. After holding mesalamine, the heart rate returned to normal within five days.
Michael Krzyzak, Anupam Gupta, Stephen Mulrooney, Evgeny Antonov   +3 more
openaire   +2 more sources

Design and Preparation of Copper(II)–Mesalamine Complex Functionalized on Silica-Coated Magnetite Nanoparticles and Study of Its Catalytic Properties for Green and Multicomponent Synthesis of Highly Substituted 4H-Chromenes and Pyridines

ACS Omega, 2022
In the present study, a green and ecofriendly nanocatalyst was synthesized through functionalization of 2,4,6-trichloro-1,3,5-triazine (TCT) and mesalamine on silica-coated magnetic nanoparticles (MNPs), then coordination with Cu2+ without agglomeration,
Hooman Taherkhani, A. Ramazani, S. Sajjadifar, Hamideh Aghahossieini, A. Rezaei   +4 more
semanticscholar   +1 more source