Results 31 to 40 of about 1,146,077 (364)
Cells, 2019 Mesenchymal stem cell (MSC)-sourced secretome, defined as the set of MSC-derived bioactive factors (soluble proteins, nucleic acids, lipids and extracellular vesicles), showed therapeutic effects similar to those observed after transplantation of MSCs ...
C. Harrell +5 more
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BMC Cancer, 2019 Background Cell cycle analysis is important for cancer research. However, available methodologies have drawbacks including limited categorisation and reliance on fixation, staining or transformation.
Jared M. Campbell +7 more
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Hematology, Transfusion and Cell Therapy, 2019 Background: Mesenchymal stem cells have immense potential in stem cell-based therapies, however there is a pre-requisite to develop a curative cell dose. Adipose tissue-derived mesenchymal stem cells are promising mainly due to their potential abundance,
Tanya Debnath, Lakshmi Kiran Chelluri
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Mesenchymal stem cell-derived extracellular vesicles: novel frontiers in regenerative medicine
Stem cell research & therapeutics, 2018 Mesenchymal stem cells (MSCs) are multipotent stem cells that have gained significant attention in the field of regenerative medicine. The differentiation potential along with paracrine properties of MSCs have made them a key option for tissue repair ...
S. Keshtkar, N. Azarpira, M. Ghahremani
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Science Translational Medicine, 2020 Glioblastoma-associated endothelial cells transform into mesenchymal stem cell–like cells via Wnt/β-catenin, inducing tumor resistance to chemotherapy.
Menggui Huang +15 more
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Homing of Mesenchymal Stem Cells [PDF]
Transfusion Medicine and Hemotherapy, 2008 SUMMARY: Mesenchymal stem cells (MSCs) are primarily fibroblast-like cells. Yet, once studied under conditions of shear stress when flowing along endothelial cells in vitro or in blood vessels, as well as in classic migration assays such as chemotaxis assays, MSCs have recently been found to function similarly to leukocytes in many ways.
Reinhard, Henschler +2 more
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The emerging antioxidant paradigm of mesenchymal stem cell therapy
Stem Cells Translational Medicine, 2020 Mesenchymal stem cells (multipotent stromal cells; MSCs) have been under investigation for the treatment of diverse diseases, with many promising outcomes achieved in animal models and clinical trials.
Rhian Stavely, K. Nurgali
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Mesenchymal stem cells and their microenvironment
Stem Cell Research & Therapy, 2022 AbstractMesenchymal stem cells (MSCs), coming from a wide range of sources, have multi-directional differentiation ability. MSCs play vital roles in immunomodulation, hematopoiesis and tissue repair. The microenvironment of cells often refers to the intercellular matrix, other cells, cytokines and humoral components.
Jiaxi Liu +6 more
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Haematologica, 2010 Background Bone marrow mesenchymal stem cells support proliferation and differentiation of hematopoietic progenitor cells in vitro. Since these cells constitute a rare subset of bone marrow cells, mesenchymal stem cell preparations for clinical purposes ...
Alexandra Briquet +5 more
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Challenges and Controversies in Human Mesenchymal Stem Cell Therapy
Stem Cells International, 2019 Stem cell therapy is being intensely investigated within the last years. Expectations are high regarding mesenchymal stem cell (MSC) treatment in translational medicine. However, many aspects concerning MSC therapy should be profoundly defined.
B. Lukomska +5 more
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