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Mesenchymal Stem Cells [PDF]

open access: yesCell Transplantation, 2011
Stem cells have two features: the ability to differentiate along different lineages and the ability of self-renewal. Two major types of stem cells have been described, namely, embryonic stem cells and adult stem cells. Embryonic stem cells (ESC) are obtained from the inner cell mass of the blastocyst and are associated with tumorigenesis, and the use ...
Dah-Ching Ding   +2 more
  +8 more sources

Human mesenchymal stem cells [PDF]

open access: yesCell Proliferation, 2021
AbstractMesenchymal stem cells (MSCs) have attracted great interest for cell therapy and tissue regeneration due to their self‐renewal capacity, multipotency and potent immunomodulatory effects on immune cells. However, heterogeneity of MSCs has become a prominent obstacle to limit their translation into practice, as cells from different tissue sources
Xiaoyong Chen   +23 more
openaire   +2 more sources

Mesenchymal Stem/Stromal Cells Derived from Cervical Cancer Promote M2 Macrophage Polarization

open access: yesCells, 2023
Macrophages with the M2 phenotype promote tumor development through the immunosuppression of antitumor immunity. We previously demonstrated the presence of mesenchymal stem/stromal cells (MSCs) in cervical cancer (CeCa-MSCs), suggesting an immune ...
Víctor Adrián Cortés-Morales   +10 more
doaj   +1 more source

Mesenchymal Stem Cells

open access: yesInflammation and Regeneration, 2013
The multipotential progenitor cells called ,Mesenchymal Stem Cells" (MSC) are capable of differrentiation at least into bone, cartilage, and adipose tissues. The commonly recognized role of these cells is the formation of connective tissue which participates in formation of every organ.
Alun Wall, Tim Board
  +9 more sources

In Vitro Evidence of Differential Immunoregulatory Response between MDA-MB-231 and BT-474 Breast Cancer Cells Induced by Bone Marrow-Derived Mesenchymal Stromal Cells Conditioned Medium

open access: yesCurrent Issues in Molecular Biology, 2022
Inside tumors, cancer cells display several mechanisms to create an immunosuppressive environment. On the other hand, by migration processes, mesenchymal stromal cells (MSCs) can be recruited by different cancer tumor types from tissues as distant as ...
Víctor M. Arenas-Luna   +6 more
doaj   +1 more source

High expression of both desmoplastic stroma and epithelial to mesenchymal transition markers associate with shorter survival in pancreatic ductal adenocarcinoma

open access: yesEuropean Journal of Histochemistry, 2022
Desmoplastic stroma (DS) and the epithelial-to-mesenchymal transition (EMT) play a key role in pancreatic ductal adenocarcinoma (PDAC) progression. To date, however, the combined expression of DS and EMT markers, and their association with variations in
Damián Sánchez-Ramírez   +15 more
doaj   +1 more source

The Beneficial Effects of Herbal Therapy (Zayesh Booalidaroo + Safoof-e Hefz + Royal Jelly) on Male Infertility [PDF]

open access: yesResearch in Molecular Medicine, 2023
Background: Several studies have recently been conducted on herbal plants due to their growing medicinal usage. Since it is estimated that male partner causes 40% of infertility, we aimed to examine the effects of herbal combinations, including Zayesh ...
Leila Naserpour   +6 more
doaj  

Investigation of the limits of nanoscale filopodial interactions [PDF]

open access: yes, 2014
Mesenchymal stem cells are sensitive to changes in feature height, order and spacing. We had previously noted that there was an inverse relationship between osteoinductive potential and feature height on 15-, 55- and 90 nm-high titania nanopillars, with ...
Dalby, Matthew J.   +5 more
core   +5 more sources

Impact of sitagliptin on endometrial mesenchymal stem-like progenitor cells : a randomised, double-blind placebo-controlled feasibility trial [PDF]

open access: yes, 2020
Background: Recurrent pregnancy loss (RPL) is associated with the loss of endometrial mesenchymal stem-like progenitor cells (eMSC). DPP4 inhibitors may increase homing and engraftment of bone marrow-derived cells to sites of tissue injury.
Brighton, Paul (Paul J.)   +13 more
core   +1 more source

Human Bone Marrow Mesenchymal Stem/Stromal Cells Exposed to an Inflammatory Environment Increase the Expression of ICAM-1 and Release Microvesicles Enriched in This Adhesive Molecule: Analysis of the Participation of TNF-α and IFN-γ

open access: yesJournal of Immunology Research, 2020
Bone marrow mesenchymal stem/stromal cells (BM-MSCs) have immunoregulatory capacity; therefore, they have been used in different clinical protocols in which it is necessary to decrease the immune response.
Juan J. Montesinos   +6 more
doaj   +1 more source

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