Results 21 to 30 of about 1,388,416 (396)

Mesenchymal stem cells

Annals of Medicine, 2005
About 40 years ago Friedenstein described stromal cells in the bone marrow that were spindle shaped and proliferate to form colonies. These cells attach to plastic and are able to differentiate under defined in vitro conditions into multiple cell types present in many different tissues, e.g. osteoblasts, chondroblasts, adipocytes, etc.
Mark F Pittenger, Gabriel Mbalaviele, Marcia Black, Joseph D Mosca, Daniel R Marshak   +4 more
openaire   +3 more sources

Caspases and p38 MAPK regulate endothelial cell adhesiveness for mesenchymal stem cells. [PDF]

PLoS ONE, 2013
Mesenchymal stem cells natively circulating or delivered into the blood stream home to sites of injury. The mechanism of mesenchymal stem cell homing to sites of injury is poorly understood.
Irina A Potapova, Ira S Cohen, Sergey V Doronin   +2 more
doaj   +1 more source

Mesenchymal stem cell-based therapy for ischemic stroke [PDF]

, 2016
Ischemic stroke represents a major, worldwide health burden with increasing incidence. Patients affected by ischemic strokes currently have few clinically approved treatment options available.
Anderson, JD, Bardini, RL, Bauer, G, Bramlett, CS, Chedin, F, Contreras, Z, Dunbar, GL, El-Andaloussi, S, Fiehn, O, Fink, KD, Fury, B, Hendrix, KJ, Hoon, M, Hwang, B, Johansson, HJ, Lehtiö, J, Mulligan, MS, Nolta, JA, Pham, MT, Rossignol, J, Showalter, M   +20 more
core   +2 more sources

Influencing the secretion of myogenic factors from mesenchymal stem cells. [PDF]

, 2014
Mounting evidence indicates that the regenerative effect of mesenchymal stem cells in skeletal muscle is related to the secretion of factors that stimulate resident myogenic cells.
Smith, Lucas R
core   +1 more source

Mesenchymal Stem Cells

Experimental Biology and Medicine, 2001
Within the bone marrow stroma there exists a subset of nonhematopoietic cells referred to as mesenchymal stem or mesenchymal progenitor cells. These cells can be ex vivo expanded and induced, either in vitro or in vivo, to terminally differentiate into osteoblasts, chondrocytes, adipocytes, tenocytes, myotubes, neural cells, and hematopoietic ...
Minguell, JJ, Erices, A, Conget, P
openaire   +6 more sources

The Impact of Mesenchymal Stem Cells on Differentiation of Hematopoietic Stem Cells [PDF]

Advanced Pharmaceutical Bulletin, 2015
Bone marrow microenvironment contains cellular and acellular compartments. The cellular compartment includes hematopoietic stem cells, mesenchymal stem cells and some other stromal cell types, while the acellular compartment is composed of scaffold ...
Mahshid Saleh, karim Shamsasanjan, Aliakbar Movassaghpourakbari, Parvin Akbarzadehlaleh, Zahra Molaeipour   +4 more
doaj   +1 more source

Differential marker expression by cultures rich in mesenchymal stem cells [PDF]

, 2013
Background: Mesenchymal stem cells have properties that make them amenable to therapeutic use. However, the acceptance of mesenchymal stem cells in clinical practice requires standardized techniques for their specific isolation.
Adra, Chaker, Al-Alwan, Monther, Al-Humaidan, Hind, Al-Mazrou, Amer, Alaiya, Ayodele, Gaafar, Ameera, Ghebeh, Hazem, Kanaan, Imaduddin, Pradez, Christian Benedict, Pulicat, Manogaran S, Shinwari, Zakia, Sleiman, Ghida Majed, Wetzig, Andrew   +12 more
core   +1 more source

Early Acquisition of Neural Crest Competence During hESCs Neuralization [PDF]

, 2010
Background: Neural crest stem cells (NCSCs) are a transient multipotent embryonic cell population that represents a defining characteristic of vertebrates.
Bronner-Fraser, Marianne, Cattarossi, Giulio, Cimadamore, Flavio, Curchoe, Carol Lynn, Maurer, Jochen, McKeown, Sonja J., Nilbratt, Mats, Snyder, Evan Y., Terskikh, Alexey V.   +8 more
core   +8 more sources

Identification of Diagnostic Biomarkers by Bioinformatics Analysis in the Inflamed and Non-inflamed Intestinal Mucosa of Patients With Crohn’s Disease

Research in Molecular Medicine, 2021
Background: Crohn’s Disease (CD) is a type of inflammatory bowel disease that, despite its unknown etiology, is generally associated with genetics, immune system, and environmental factors. In this study, we uncover transcriptional signatures in patients
Mohsen Sheykhhasan, Hoda Fazaeli, Azar Sheikholeslami, Seyed Abbas Seyedebrahimi, Seyed Jalal Eshagh Hoseini, Naser Kalhor   +5 more
doaj  

Odontogenic MSC Heterogeneity: Challenges and Opportunities for Regenerative Medicine

Frontiers in Physiology, 2022
Cellular heterogeneity refers to the genetic and phenotypic differences among cells, which reflect their various fate choices, including viability, proliferation, self-renewal probability, and differentiation into different lineages.
Yuan Chen, Zhaoyichun Zhang, Xiaoxue Yang, Anqi Liu, Shiyu Liu, Jianying Feng, Kun Xuan   +6 more
doaj   +1 more source