Results 1 to 10 of about 138,445 (169)
Mesenchymal stromal cells in the thymus
Inflammation and Regeneration, 2022 The microenvironment of the thymus is composed of a group of stromal cells that include endoderm-derived thymic epithelial cells (TECs) and mesenchymal stromal cells such as fibroblasts and serves as a site for the development of T cells.
Takeshi Nitta
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Umbilical cord mesenchymal stromal cells—from bench to bedside
Frontiers in Cell and Developmental Biology, 2022 In recent years, mesenchymal stromal cells (MSCs) have generated a lot of attention due to their paracrine and immuno-modulatory properties. mesenchymal stromal cells derived from the umbilical cord (UC) are becoming increasingly recognized as having ...
Shashank Chetty +9 more
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Frontiers in Pharmacology, 2023 Myocardial injury is a major pathological factor that causes death in patients with heart diseases. In recent years, mesenchymal stromal cells (MSCs) have been generally used in treating many diseases in animal models and clinical trials.
Wenguang Chang, Peifeng Li
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Mesenchymal stromal cells for osteonecrosis [PDF]
Journal of Translational Medicine, 2020 AbstractOsteonecrosis (ON) is an acquired debilitating skeletal disorder, which is caused by a multitude of traumatic and non-traumatic etiological factors. Vascular damage, mechanical stress and increased intraosseous pressure have been discussed as contributors to ON.
S. Elgaz, H. Bonig, P. Bader
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Failure of intravenous or intracardiac delivery of mesenchymal stromal cells to improve outcomes after focal traumatic brain injury in the female rat. [PDF]
PLoS ONE, 2015 Mesenchymal stromal cells secrete a variety of anti-inflammatory factors and may provide a regenerative medicine option for the treatment of traumatic brain injury.
L Christine Turtzo +10 more
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Biochemistry and Biophysics Reports, 2023 Mesenchymal stromal cells in the muscle layer of the large intestine are essential for the regulation of intestinal motility. They form electrogenic syncytia with the smooth muscle and interstitial cells of Cajal (ICCs) to regulate smooth muscle ...
Takashi Chaen +6 more
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The Stromal Activity of Mesenchymal Stromal Cells [PDF]
Transfusion Medicine and Hemotherapy, 2008 SUMMARY: The mechanism that regulates self-renewal and differentiation of hematopoietic stem cells (HSC) is a central question in stem cell biology that might ultimately lead to reliable protocols for in vitro expansion of HSC. Cellular fate is governed by cell-cell interaction with the microenvironment in the bone marrow, the stem cell niche ...
Wolfgang, Wagner +2 more
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Mesenchymal stromal cells in hematopoietic cell transplantation [PDF]
Blood Advances, 2020 Abstract Mesenchymal stromal cells (MSCs) are widely recognized to possess potent immunomodulatory activity, as well as to stimulate repair and regeneration of diseased or damaged tissue. These fundamental properties suggest important applications in hematopoietic cell transplantation.
Andre J. Burnham +2 more
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Evidences of early senescence in multiple myeloma bone marrow mesenchymal stromal cells. [PDF]
PLoS ONE, 2013 BACKGROUND: In multiple myeloma, bone marrow mesenchymal stromal cells support myeloma cell growth. Previous studies have suggested that direct and indirect interactions between malignant cells and bone marrow mesenchymal stromal cells result in ...
Thibaud André +6 more
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Mesenchymal stromal cells and autoimmunity [PDF]
International Immunology, 2017 Abstract Mesenchymal stromal cells (MSCs) are committed progenitors of mesodermal origin that are found virtually in every organ and exhibit multilineage differentiation into osteocytes, adipocytes and chondrocytes. MSCs also mediate a wide spectrum of immunoregulatory activities that usually dampen innate and adaptive immune responses ...
Lizzia Raffaghello, Vito Pistoia
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