Results 41 to 50 of about 138,445 (169)

Mesenchymal Stromal Cells for Antineoplastic Drug Loading and Delivery

Medicines, 2017
Mesenchymal stromal cells are a population of undifferentiated multipotent adult cells possessing extensive self-renewal properties and the potential to differentiate into a variety of mesenchymal lineage cells.
Francesco Petrella, Isabella Rimoldi, Stefania Rizzo, Lorenzo Spaggiari   +3 more
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Mesenchymal stromal cells: more than inhibitory cells [PDF]

Leukemia, 2011
Mesenchymal stem cells, cautiously re-named recently multipotent mesenchymal stromal cells (MSCs) because of their heterogeneous multipotency at single cell level and their similarities with fibroblasts, have been strongly suggested in the last decade as powerful inhibitory cells for the vast majority of immune effector cells.
openaire   +2 more sources

Co-transplantation of Human Fetal Mesenchymal and Hematopoietic Stem Cells in Type 1 Diabetic Mice Model

Frontiers in Endocrinology, 2019
Introduction: Cell therapy can overcome the limitation of conventional treatments (including different medications and β cell replacement) for type 1 diabetes.
Babak Arjmand, Babak Arjmand, Parisa Goodarzi, Hamid Reza Aghayan, Moloud Payab, Fakher Rahim, Sepideh Alavi-Moghadam, Fereshteh Mohamadi-jahani, Bagher Larijani   +8 more
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Relevance of the mevalonate biosynthetic pathway in the regulation of bone marrow mesenchymal stromal cell-mediated effects on T-cell proliferation and B-cell survival

Haematologica, 2011
Background Bone marrow mesenchymal stromal cells can suppress T-lymphocyte proliferation but promote survival of normal and malignant B cells, thus representing a possible target for new therapeutic schemes.
Alessandra Musso, Maria Raffaella Zocchi, Alessandro Poggi   +2 more
doaj   +1 more source

Interplay between mesenchymal stromal cells and the immune system after transplantation: implications for advanced cell therapy in the retina

Neural Regeneration Research
Advanced mesenchymal stromal cell-based therapies for neurodegenerative diseases are widely investigated in preclinical models. Mesenchymal stromal cells are well positioned as therapeutics because they address the underlying mechanisms of ...
María Norte-Muñoz, David García-Bernal, Diego García-Ayuso, Manuel Vidal-Sanz, Marta Agudo-Barriuso   +4 more
doaj   +1 more source

Mesenchymal stem cells: the fibroblasts’ new clothes?

Haematologica, 2009
Mesenchymal stem cells are adherent stromal cells, initially isolated from the bone marrow, characterized by their ability to differentiate into mesenchymal tissues such as bone, cartilage and fat.
Muzlifah A. Haniffa, Matthew P. Collin, Christopher D. Buckley, Francesco Dazzi   +3 more
doaj   +1 more source

Mesenchymal stromal cells – Where art thou? [PDF]

Journal of Hepatology, 2015
Mesenchymal stromal cells (MSC) have potent immunomodulatory properties which have led to them being considered as a novel therapeutic modality across a wide range of clinical areas including conditions such as steroid refractory paediatric graft vs. host disease (GVHD) where they are licensed in New Zealand and Canada.
Vasanthy, Vigneswara, Philip N, Newsome
openaire   +2 more sources

Impaired expression of DICER, DROSHA, SBDS and some microRNAs in mesenchymal stromal cells from myelodysplastic syndrome patients

Haematologica, 2012
Background Recent findings suggest that a specific deletion of Dicer1 in mesenchymal stromal cell-derived osteoprogenitors triggers several features of myelodysplastic syndrome in a murine model.
Carlos Santamaría, Sandra Muntión, Beatriz Rosón, Belén Blanco, Olga López-Villar, Soraya Carrancio, Fermín M. Sánchez-Guijo, María Díez-Campelo, Stela Alvarez-Fernández, María E. Sarasquete, Javier de las Rivas, Marcos González, Jesús F. San Miguel, María Consuelo del Cañizo   +13 more
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Mesenchymal Stromal Cells and Viral Infection [PDF]

Stem Cells International, 2015
Mesenchymal Stromal Cells (MSCs) are a subset of nonhematopoietic adult stem cells, readily isolated from various tissues and easily culture-expandedex vivo. Intensive studies of the immune modulation and tissue regeneration over the past few years have demonstrated the great potential of MSCs for the prevention and treatment of steroid-resistant acute
Maytawan Thanunchai, Suradej Hongeng, Arunee Thitithanyanont   +2 more
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A spiked human proteomic dataset from human osteogenic differentiated BMSCs and ASCs for use as a spectral library, for modelling pathways as well as protein mapping

Data in Brief, 2019
This article describes a mass spectrometry data set generated from osteogenic differentiated bone marrow stromal cells (BMSCs) and adipose tissue derived stromal cells (ASCs) of a 24-year old healthy donor.
Mehran Dadras, Katrin Marcus, Johannes Maximilian Wagner, Christoph Wallner, Mustafa Becerikli, Henriette Jaurich, Stephanie Dittfeld, Marcus Lehnhardt, Bettina Serschnitzki, Annika Guntermann, Lukas Schilde, Björn Behr, Caroline May   +12 more
doaj   +1 more source