Results 61 to 70 of about 138,445 (169)

Magnetic resonance imaging tracing of superparamagnetic iron oxide nanoparticle–labeled mesenchymal stromal cells for repairing spinal cord injury

Neural Regeneration Research
Mesenchymal stromal cell transplantation is an effective and promising approach for treating various systemic and diffuse diseases. However, the biological characteristics of transplanted mesenchymal stromal cells in humans remain unclear, including cell
Xiaoli Mai, Yuanyuan Xie, Zhichong Wu, Junting Zou, Jiacheng Du, Yunpeng Shen, Hao Liu, Bo Chen, Mengxia Zhu, Jiong Shi, Yang Chen, Bing Zhang, Zezhang Zhu, Bin Wang, Ning Gu   +14 more
doaj   +1 more source

Identifying TNFSF4low-MSCs superiorly treating idiopathic pulmonary fibrosis through Tregs differentiation modulation

Stem Cell Research & Therapy
Background Idiopathic pulmonary fibrosis is a progressive lung disorder, presenting clinically with symptoms such as shortness of breath and hypoxemia. Despite its severe prognosis and limited treatment options, the pathogenesis of idiopathic pulmonary ...
Yuanyuan Xie, Qing Yi, Congwang Xu, Yaping Wang, Yue Jiang, Yirui Feng, Liudi Wang, Hui Yang, Yingwei Zhang, Bin Wang   +9 more
doaj   +1 more source

Mesenchymal Stem/ Stromal Cells metabolomic and bioactive factors profiles: A comparative analysis on the umbilical cord and dental pulp derived Stem/ Stromal Cells secretome.

PLoS ONE, 2019
Mesenchymal Stem/ Stromal Cells assume a supporting role to the intrinsic mechanisms of tissue regeneration, a feature mostly assigned to the contents of their secretome.
Ana Rita Caseiro, Sílvia Santos Pedrosa, Galya Ivanova, Mariana Vieira Branquinho, André Almeida, Fátima Faria, Irina Amorim, Tiago Pereira, Ana Colette Maurício   +8 more
doaj   +1 more source

A Nonenzymatic and Automated Closed-Cycle Process for the Isolation of Mesenchymal Stromal Cells in Drug Delivery Applications

Stem Cells International, 2018
The adipose tissue is a good source of mesenchymal stromal cells that requires minimally invasive isolation procedures. To ensure reproducibility, efficacy, and safety for clinical uses, these procedures have to be in compliant with good manufacturing ...
Valentina Coccè, Anna Brini, Aldo Bruno Giannì, Valeria Sordi, Angiola Berenzi, Giulio Alessandri, Carlo Tremolada, Silvia Versari, Antonio Bosetto, Augusto Pessina   +9 more
doaj   +1 more source

Human mesenchymal stromal cells transplanted into mice stimulate renal tubular cells and enhance mitochondrial function

Nature Communications, 2017
Mesenchymal stromal cells drive renal regeneration following injury. Here, the authors show that human mesenchymal stromal cells, when transplanted into mice with acute kidney injury, stimulate renal tubular cell growth and enhance mitochondrial function
Luca Perico, Marina Morigi, Cinzia Rota, Matteo Breno, Caterina Mele, Marina Noris, Martino Introna, Chiara Capelli, Lorena Longaretti, Daniela Rottoli, Sara Conti, Daniela Corna, Giuseppe Remuzzi, Ariela Benigni   +13 more
doaj   +1 more source

Identification of a common mesenchymal stromal progenitor for the adult haematopoietic niche

Nature Communications, 2016
How the environment of the niche regulates haematopoietic stem cells (HSC) is unclear. Here, the authors identify a mesenchymal stromal progenitor hierarchy and identify Sca1+ cells as common progenitors for mesenchymal stromal cells in the adult niche ...
Xingbin Hu, Mayra Garcia, Lihong Weng, Xiaoman Jung, Jodi L. Murakami, Bijender Kumar, Charles D. Warden, Ivan Todorov, Ching-Cheng Chen   +8 more
doaj   +1 more source

Human intestinal organoid-derived PDGFRα + mesenchymal stroma enables proliferation and maintenance of LGR4 + epithelial stem cells

Stem Cell Research & Therapy
Background Intestinal epithelial cells derived from human pluripotent stem cells (hPSCs) are generally maintained and cultured as organoids in vitro because they do not exhibit adhesion when cultured. However, the three-dimensional structure of organoids
JunLong Chen, Shinichiro Horiuchi, So Kuramochi, Tomoyuki Kawasaki, Hayato Kawasumi, Saeko Akiyama, Tomoki Arai, Kenichi Morinaga, Tohru Kimura, Tohru Kiyono, Hidenori Akutsu, Seiichi Ishida, Akihiro Umezawa   +12 more
doaj   +1 more source

Mesenchymal stromal cells as cancer promoters

Oncogene
Mesenchymal stromal cells (MSCs) are important cellular constituents of tumor stroma that play an active role in tumor development. Complex interactions between MSCs and cancer promote tumor progression by creating a favorable milieu for tumor cell proliferation, angiogenesis, motility, invasion, and metastasis.
Roula Antoon, Nina Overdevest, Amr H. Saleh, Armand Keating   +3 more
openaire   +2 more sources

Mesenchymal Stromal Cells

Biology of Blood and Marrow Transplantation, 2007
Horwitz, Edwin M., Andreef, Michael, Frassoni, Francesco   +2 more
openaire   +1 more source

Intramuscular administration of mesenchymal stromal cells in a cat with asthma: case report. [PDF]

J Vet Intern Med
Anderson de Oliveira P, Passos Maeda C, Barbalho Bianchi P, Baracho Trindade Hill JE, Baracho Trindade Hill A.   +4 more
europepmc   +1 more source