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Inhibition of EZH2 Promotes Human Embryonic Stem Cell Differentiation into Mesoderm by Reducing H3K27me3 [PDF]
Stem Cell Reports, 2017 Mesoderm derived from human embryonic stem cells (hESCs) is a major source of the mesenchymal stem/stromal cells (MSCs) that can differentiate into osteoblasts and chondrocytes for tissue regeneration.
Yongxin Yu +6 more
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eLife, 2023 The enteric nervous system (ENS), a collection of neural cells contained in the wall of the gut, is of fundamental importance to gastrointestinal and systemic health.
Subhash Kulkarni +17 more
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Biomedicines, 2023 Differentiation of induced pluripotent stem cells to a range of target cell types is ubiquitous in monolayer culture. To further improve the phenotype of the cells produced, 3D organoid culture is becoming increasingly prevalent.
Adam Mitchell +7 more
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Mature Mediastinal Teratoma [PDF]
Journal of Clinical and Diagnostic Research, 2015 A teratoma is a tumour with tissue or organ components resembling normal derivatives of more than one germ layer. We present a case of mediastinal mature teratoma as they have a low incidence rate.
Chikka Narasimhaiah Anushree +1 more
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Evidence for a Role of the Lateral Ectoderm in Drosophila Mesoderm Invagination
Frontiers in Cell and Developmental Biology, 2022 The folding of two-dimensional epithelial sheets into specific three-dimensional structures is a fundamental tissue construction mechanism in animal development.
Hanqing Guo, Shicheng Huang, Bing He
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Pharmaceuticals, 2020 The field of regenerative medicine utilizes a wide array of technologies and techniques for repairing and restoring function to damaged tissues. Among these, stem cells offer one of the most potent and promising biological tools to facilitate such goals.
Caitlin Priester +3 more
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Cell Reports, 2022 Summary: Liver sinusoidal endothelial cells (LSECs) form the predominant microvasculature in the liver where they carry out many functions including the secretion of coagulation factor VIII (FVIII).
Blair K. Gage +4 more
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Fate mapping identifies the origin of SHF/AHF progenitors in the chick primitive streak [PDF]
, 2012 Heart development depends on the spatio-temporally regulated contribution of progenitor cells from the primary, secondary and anterior heart fields. Primary heart field (PHF) cells are first recruited to form a linear heart tube; later, they contribute ...
Camp, E. +2 more
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Visceral organ morphogenesis via calcium-patterned muscle constrictions
eLife, 2022 Organ architecture is often composed of multiple laminar tissues arranged in concentric layers. During morphogenesis, the initial geometry of visceral organs undergoes a sequence of folding, adopting a complex shape that is vital for function.
Noah P Mitchell +5 more
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