Results 131 to 140 of about 94,714 (283)

The Embryonic Development of the Cotylean Polyclad Phrikoceros jannetae

Acta Zoologica, EarlyView.
ABSTRACT Polyclads exhibit distinct developmental modes ranging from direct to indirect development, with several transitional stages also recognised. The existence of an indirect developmental mode in polyclads with a planktonic life history stage in the form of a free‐swimming larva is unique among all free‐living flatworms and makes polyclads a ...
Mehrez Gammoudi, Bernhard Egger, Isabel L. Dittmann, Verónica N. Bulnes, Pavel Tomancak, Abdel Halim Harrath, Johannes Girstmair   +6 more
wiley   +1 more source

Ethical and Regulatory Considerations in the Clinical Translation of Pluripotent Stem Cell‐Derived NK Cell Therapies

Cell Proliferation, EarlyView.
Advancements in the generation of human pluripotent stem cell‐derived natural killer (PSC‐NK) cells have attracted considerable attention within the biomedical research community, offering a promising off‐the‐shelf technique for universal immune therapy.
Qianwen Chen, Jianwei Lv, Xinwei Xie, Hanlin Zhu, Zhenyu Xiao, Yaojin Peng   +5 more
wiley   +1 more source

Three-Dimensional Trilineage Differentiation Conditions for Human Induced Pluripotent Stem Cells

Bioengineering
Human induced pluripotent stem cells (hiPSCs) hold great potential for regenerative medicine. However, optimizing their differentiation into specific lineages within three-dimensional (3D) scaffold-based culture systems that mimic in vivo environments ...
Md Sharifur Rahman, Guangyan Qi, Quan Li, Xuming Liu, Jianfa Bai, Mingshun Chen, Anthony Atala, Xiuzhi Susan Sun   +7 more
doaj   +1 more source

Hcfc1 and Ogt Mediate Zebrafish CNS Regeneration Through Hippo/Yap Signalling

Cell Proliferation, EarlyView.
This work identifies Hcfc1 and Ogt as key regulators of zebrafish CNS regeneration through modulation of Hippo/Yap signalling. Loss of Hcfc1 or Ogt activity inhibition impairs regeneration, which is restored by Yap overexpression, revealing a new regulatory axis that enhances CNS regenerative capacity.
Priyanka P. Srivastava, Sidharth Bhasin, Poonam Sharma, Omkar Mahadeo Desai, Kshitiz Yadav, Ayushma, Rohan Chakraborty, Suhel Parvez, Rajesh Ramachandran, Shilpi Minocha   +9 more
wiley   +1 more source

Mechanobiology in Stem Cell‐Based Bioprinting

Cell Proliferation, EarlyView.
Mechanobiology in stem cell‐based bioprinting is an emerging field that bridges the mechanical conditions of the bioprinting process with the regulation of stem cell behaviour for engineering living tissues. Stresses encountered during bioprinting, together with the mechanical properties of bioinks, play a critical role in regulating stem cell ...
Supeng Ding, Tiankun Liu, Rui Yao
wiley   +1 more source

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

The FEBS Journal, EarlyView.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio, Ana Lucia Cuadros Gamboa, Martina Bertocchi, Filippo Chiesa, Francesca Cargnin, Ettore Mosca, Paride Pelucchi, Viviana Tritto, Stefania Corti, Isabella Ceccherini, Paola Riva, Roberta Benfante, Diego Fornasari   +12 more
wiley   +1 more source

Mesoderm [PDF]

, 2020
openaire   +1 more source

Intra‐Tissue Bacteriome and Cellular Profiles in Periodontal Granulation Tissue From Osseous Defects and Extraction Sockets

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To investigate the intra‐tissue bacteriome and cell profiles within periodontal granulation tissue (PGT) for exploring the biological essence and translational potentials. Materials and Methods PGT samples were collected from 49 patients with severe periodontitis—including those from osseous defects (GT) during periodontal surgery ...
Tianfan Cheng, Tianle Li, Tsz Yung Wong, Beibei Chen, Chongshan Liao, Xun Ding, Hui Chen, Wei Qiao, George Pelekos, Lijian Jin   +9 more
wiley   +1 more source

Mapping the murine TMJ glenoid fossa over development, homeostasis and in response to disease

Journal of Anatomy, EarlyView.
The fibrocartilage of the murine glenoid fossa and condyle of the temporomandibular joint are shown to form at distinct times with distinct molecular identities. Changes in the condyle during disease lead to remodelling of the fossa to maintain joint alignment.
Ticha Tuwatnawanit, Denisa Belisova, Zuzana Sumbalova Koledova, Neal Anthwal, Abigail S. Tucker   +4 more
wiley   +1 more source

Is the temporomandibular joint affected by rheumatoid arthritis? A comparative investigation with knee arthritis in an experimental rat model

Journal of Anatomy, EarlyView.
Animals were sensitized with mBSA emulsified in CFA/IFA and subsequently received three intra‐articular injections of mBSA into either the TMJ or the knee (once per week). Mechanical hyperalgesia was assessed using electronic von Frey testing after arthritis establishment at 24 h or 7 days following the third intra‐articular injection.
Ana Carolina de Figueiredo Costa, Luane Macedo de Sousa, Delane Viana Gondim   +2 more
wiley   +1 more source