Results 171 to 180 of about 64,865 (357)
Editor's evaluation: Glycolytic flux-signaling controls mouse embryo mesoderm development
, 2022 Joshua M. Brickman
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British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Apelin and Elabela are endogenous ligands of the apelin receptor (apelin receptor/APJ), a GPCR involved in cardiovascular regulation and body fluid homeostasis. The human receptor contains a conserved disulfide bridge linking the N‐terminal domain to extracellular loop 3 (ECL3) via Cys19 and Cys281, forming a structural ...
Chloé Bonef +11 more
wiley +1 more source
Can gastric endoderm change the regionally specific inducing ability of presumptive small intestinal mesoderm? [PDF]
, 2000 B.B. Rawdon
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Cell Proliferation, EarlyView.The hfPSC‐LCs could be established from naïve hESCs, conventional hESCs, hiPSCs, and human blastocysts. The hfPSC‐LCs hold robust capacity for three germ layers, hPGCLCs, and hALPCs. ABSTRACT Human embryos undergo pivotal morphogenetic remodelling shortly after implantation. The understanding of this crucial stage is severely impeded by the scarcity of
Xiaoxiao Wang +11 more
wiley +1 more source
Myoblast determination in the somatic and visceral mesoderm depends on Notch signalling as well as onmilliways(miliAlk) as receptor for Jeb signalling [PDF]
, 2004 Christiana Stute +4 more
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Monocytes Derived From Human Pluripotent Stem Cells Engineered for Detection of Pyrogens
Cell Proliferation, EarlyView.In summary, we have developed a monocyte‐based reporter system using hESC‐Mono for interrogating the NF‐κB signalling axis, a central pathway governing pyrogenic responses. Our platform enables rapid and dose‐dependent detection of both endotoxins (LPS) and non‐endotoxins (LTA and Zymosan).
Jingjing Liu +8 more
wiley +1 more source