Results 181 to 190 of about 64,865 (357)

Lateral thinking in syndromic congenital cardiovascular disease

open access: yesDisease Models & Mechanisms, 2023
Agnese Kocere   +3 more
doaj   +1 more source

iPSC‐Derived iNK Progenitors Engraft and Generate NK Cells in Unconditioned and Autologous Immune Humanized Mice

open access: yesCell Proliferation, EarlyView.
Infusion of CXCR4‐expressing iNK progenitor (iNKP) cells derived from iPSCs can continuously generate iNK cells in an unconditioned and autologous PBMC humanised hIL15 mouse model. iNKP cell therapy has the potential to treat patients without the requirement for prior lymphodepletion. ABSTRACT NK cells exhibit inherently short persistence in vivo. Allo‐
Min Zhang   +14 more
wiley   +1 more source

Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease

open access: yesCell Proliferation, EarlyView.
Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik   +10 more
wiley   +1 more source

Glycolytic flux-signaling controls mouse embryo mesoderm development

open access: gold, 2022
Hidenobu Miyazawa   +8 more
openalex   +1 more source

Assessing the reproducibility of a bioimage analysis workflow characterising tissue flow in Drosophila

open access: yesJournal of Microscopy, EarlyView.
Abstract Reproducibility challenges in bioimage analysis are common. The proliferation of tools and workflows creates a complex ecosystem that is difficult to reproduce without deliberate, explicit reporting and support. We assess the reproducibility of Gehrels et al.(2023) as a representative bioimage analysis workflow.
Mélodie Ambroset   +4 more
wiley   +1 more source

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