Results 11 to 20 of about 99,345 (353)

Hox Genes Regulate Muscle Founder Cell Pattern Autonomously and Regulate Morphogenesis Through Motor Neurons [PDF]

, 2010
The differentiation of myoblasts to form functional muscle fibers is a consequence of interactions between the mesoderm and ectoderm. The authors examine the role of segment identity in directing these interactions by studying the role of Hox genes in ...
Dutta, Devkanya, Lewis, Edward. B., Rodrigues, Veronica, Umashankar, M., VijayRaghavan, K.   +4 more
core   +1 more source

Distinct mesoderm migration phenotypes in extra-embryonic and embryonic regions of the early mouse embryo

eLife, 2019
In mouse embryo gastrulation, epiblast cells delaminate at the primitive streak to form mesoderm and definitive endoderm, through an epithelial-mesenchymal transition.
Bechara Saykali, Navrita Mathiah, Wallis Nahaboo, Marie-Lucie Racu, Latifa Hammou, Matthieu Defrance, Isabelle Migeotte   +6 more
doaj   +1 more source

FGF ligands in Drosophila have distinct activities required to support cell migration and differentiation [PDF]

, 2009
Fibroblast growth factor (FGF) signaling controls a vast array of biological processes including cell differentiation and migration, wound healing and malignancy.
Kadam, Snehalata, McMahon, Amy, Stathopoulos, Angelike, Tzou, Phoebe   +3 more
core   +4 more sources

Recognition of H2AK119ub plays an important role in RSF1-regulated early Xenopus development

Frontiers in Cell and Developmental Biology, 2023
Polycomb group (PcG) proteins are key regulators of gene expression and developmental programs via covalent modification of histones, but the factors that interpret histone modification marks to regulate embryogenesis are less studied.
Saeid Mohammad Parast, Deli Yu, Chunxu Chen, Chunxu Chen, Chunxu Chen, Amanda J. Dickinson, Chenbei Chang, Hengbin Wang, Hengbin Wang, Hengbin Wang   +9 more
doaj   +1 more source

Quantitative imaging of the collective cell movements shaping an embryo [PDF]

, 2009
The recent development of imaging and image processing techniques, such as 4D microscopy and 3D cell tracking, enables analysis through quantification of the movement of large cell populations in vivo.
Fraser, Scott E., McMahon, Amy, Stathopoulos, Angelike, Supatto, Willy   +3 more
core   +1 more source

LGR4, Not LGR5, Enhances hPSC Hematopoiesis by Facilitating Mesoderm Induction via TGF-Beta Signaling Activation

Cell Reports, 2020
Summary: Attempts to generate functional blood cells from human pluripotent stem cells (hPSCs) remain largely unsuccessful, mainly due to the lack of understanding of the regulatory network of human hematopoiesis.
Yu Wang, Hongtao Wang, Jiaojiao Guo, Jie Gao, Mengge Wang, Meijuan Xia, Yuqi Wen, Pei Su, Ming Yang, Mingyao Liu, Lihong Shi, Tao Cheng, Wen Zhou, Jiaxi Zhou   +13 more
doaj   +1 more source

Functionally distinct roles for T and Tbx6 during mouse development

Biology Open, 2020
The mouse T-box transcription factors T and Tbx6 are co-expressed in the primitive streak and have unique domains of expression; T is expressed in the notochord, while Tbx6 is expressed in the presomitic mesoderm.
Amy K. Wehn, Deborah R. Farkas, Carly E. Sedlock, Dibya Subedi, Deborah L. Chapman   +4 more
doaj   +1 more source

The occipital lateral plate mesoderm is a novel source for vertebrate neck musculature [PDF]

, 2010
In vertebrates, body musculature originates from somites, whereas head muscles originate from the cranial mesoderm. Neck muscles are located in the transition between these regions.
Christ, B., Harel, I., Huang, R., Otto, Anthony, Patel, Ketan, Pu, Q., Tajbakhsh, S., Theis, S., Tzahor, E., Valasek, Petr   +9 more
core   +1 more source

Early patterning and specification of cardiac progenitors in gastrulating mesoderm

eLife, 2014
Mammalian heart development requires precise allocation of cardiac progenitors. The existence of a multipotent progenitor for all anatomic and cellular components of the heart has been predicted but its identity and contribution to the two cardiac ...
W Patrick Devine, Joshua D Wythe, Matthew George, Kazuko Koshiba-Takeuchi, Benoit G Bruneau   +4 more
doaj   +1 more source

The early stages of heart development: insights from chicken embryos [PDF]

, 2016
The heart is the first functioning organ in the developing embryo and the detailed understanding of the molecular and cellular mechanisms involved in its formation provides insights into congenital malformations affecting its function and therefore the ...
Alsan, Arguello, de la Cruz, de La Cruz, de la Cruz, DeHaan, Hatada, Kitajima, Le Lievre, Needham, Plein, Psychoyos, Rosenquist, Schultheiss, Stern, Tam, Vincent, Waldo, Yatskievych, Zhang   +19 more
core   +2 more sources