Results 31 to 40 of about 113,853 (284)

Distinct mesoderm migration phenotypes in extra-embryonic and embryonic regions of the early mouse embryo

open access: yeseLife, 2019
In mouse embryo gastrulation, epiblast cells delaminate at the primitive streak to form mesoderm and definitive endoderm, through an epithelial-mesenchymal transition.
Bechara Saykali   +6 more
doaj   +1 more source

Cohesin Components Stag1 and Stag2 Differentially Influence Haematopoietic Mesoderm Development in Zebrafish Embryos

open access: yesFrontiers in Cell and Developmental Biology, 2020
Cohesin is a multiprotein complex made up of core subunits Smc1, Smc3, and Rad21, and either Stag1 or Stag2. Normal haematopoietic development relies on crucial functions of cohesin in cell division and regulation of gene expression via three-dimensional
Sarada Ketharnathan   +3 more
doaj   +1 more source

Functionally distinct roles for T and Tbx6 during mouse development

open access: yesBiology Open, 2020
The mouse T-box transcription factors T and Tbx6 are co-expressed in the primitive streak and have unique domains of expression; T is expressed in the notochord, while Tbx6 is expressed in the presomitic mesoderm.
Amy K. Wehn   +4 more
doaj   +1 more source

FGF-mediated establishment of left-right asymmetry requires Rab7 function in the dorsal mesoderm in Xenopus

open access: yesFrontiers in Cell and Developmental Biology, 2022
Gastrulation denotes a very important developmental process, which includes significant structural tissue rearrangements and patterning events that shape the emerging vertebrate organism.
Jennifer Kreis   +4 more
doaj   +1 more source

Gene profiling of head mesoderm in early zebrafish development: insights into the evolution of cranial mesoderm

open access: yesEvoDevo, 2019
Background The evolution of the head was one of the key events that marked the transition from invertebrates to vertebrates. With the emergence of structures such as eyes and jaws, vertebrates evolved an active and predatory life style and radiated into ...
Huijia Wang   +2 more
doaj   +1 more source

Quantitative imaging of the collective cell movements shaping an embryo [PDF]

open access: yes, 2009
The recent development of imaging and image processing techniques, such as 4D microscopy and 3D cell tracking, enables analysis through quantification of the movement of large cell populations in vivo.
Fraser, Scott E.   +3 more
core   +1 more source

Mechanotransductive cascade of Myo-II-dependent mesoderm and endoderm invaginations in embryo gastrulation

open access: yesNature Communications, 2017
Animal development consists of a cascade of tissue differentiation and shape change. Associated mechanical signals regulate tissue differentiation. Here we demonstrate that endogenous mechanical cues also trigger biochemical pathways, generating the ...
Démosthène Mitrossilis   +11 more
semanticscholar   +1 more source

Fibroepithelial Polyp Originating from the Nasal Septum

open access: yesTurkish Archives of Otorhinolaryngology, 2019
Fibroepithelial polyp (FEP) is a rare clinical condition of mesodermal origin, covered usually by squamous epithelium, originating most frequently from the skin, genitourinary and lower respiratory tract.
Marko Stoiljkov, Aleksandar Perić
doaj   +1 more source

Cardiac differentiation of human pluripotent stem cells using defined extracellular matrix proteins reveals essential role of fibronectin

open access: yeseLife, 2022
Research and therapeutic applications using human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) require robust differentiation strategies. Efforts to improve hPSC-CM differentiation have largely overlooked the role of extracellular matrix (ECM).
Jianhua Zhang   +9 more
doaj   +1 more source

Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-cis-retinoic acid. [PDF]

open access: yes, 2018
13-cis-retinoic acid (isotretinoin, INN) is an oral pharmaceutical drug used for the treatment of skin acne, and is also a known teratogen. In this study, the molecular mechanisms underlying INN-induced developmental toxicity during early cardiac ...
Geller, Benjamin S   +9 more
core   +3 more sources

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