Results 41 to 50 of about 113,853 (284)

Global patterning of the vertebrate mesoderm [PDF]

Developmental Dynamics, 2007
AbstractWe describe recent advances in the understanding of patterning in the vertebrate post‐cranial mesoderm. Specifically, we discuss the integration of local information into global level information that results in the overall coordination along the anterioposterior axis.
Ann C. Burke, Benjamin Britton Winslow, Ryoko Takimoto-Kimura   +2 more
openaire   +3 more sources

Cell lineage and cell cycling analyses of the 4d micromere using live imaging in the marine annelid Platynereis dumerilii

eLife, 2017
Cell lineage, cell cycle, and cell fate are tightly associated in developmental processes, but in vivo studies at single-cell resolution showing the intricacies of these associations are rare due to technical limitations.
B Duygu Özpolat, Mette Handberg-Thorsager, Michel Vervoort, Guillaume Balavoine   +3 more
doaj   +1 more source

A squash and a squeeze

eLife, 2022
Advanced imaging techniques reveal details of the interactions between the two layers of the embryonic midgut that influence its ultimate shape.
Danelle Devenport
doaj   +1 more source

Evolutionary plasticity of developmental gene regulatory network architecture [PDF]

, 2007
Sea stars and sea urchins evolved from a last common ancestor that lived at the end of the Cambrian, approximately half a billion years ago. In a previous comparative study of the gene regulatory networks (GRNs) that embody the genomic program for ...
Britten, Calestani, Croce, Davidson, E. H. Davidson, Hinman, Hinman, Lee, Maruyama, Oliveri, Oliveri, Oliveri, Oliveri, Ransick, Ransick, Revilla-i-Domingo, Rizzo, Satoh, Sea Urchin Genome Sequencing Consortium, Sherwood, Tagawa, V. F. Hinman, Wada, Walton, Yuh, Yuh   +25 more
core   +4 more sources

An atlas of transcriptional, chromatin accessibility, and surface marker changes in human mesoderm development

Scientific Data, 2016
Mesoderm is the developmental precursor to myriad human tissues including bone, heart, and skeletal muscle. Unravelling the molecular events through which these lineages become diversified from one another is integral to developmental biology and ...
Pang Wei Koh, Rahul Sinha, Amira A. Barkal, Rachel M. Morganti, Angela Chen, I. Weissman, L. Ang, Anshul Kundaje, K. Loh   +8 more
semanticscholar   +1 more source

Germ layer-specific regulation of cell polarity and adhesion gives insight into the evolution of mesoderm

eLife, 2018
In triploblastic animals, Par-proteins regulate cell-polarity and adherens junctions of both ectodermal and endodermal epithelia. But, in embryos of the diploblastic cnidarian Nematostella vectensis, Par-proteins are degraded in all cells in the ...
Miguel Salinas-Saavedra, Amber Q Rock, Mark Q Martindale   +2 more
doaj   +1 more source

mNanog possesses dorsal mesoderm-inducing ability by modulating both BMP and Activin/nodal signaling in Xenopus ectodermal cells. [PDF]

PLoS ONE, 2012
BACKGROUND:In Xenopus early embryogenesis, various genes are involved with mesoderm formation. In particular, dorsal mesoderm contains the organizer region and induces neural tissues through the inhibition of bone morphogenetic protein (BMP) signaling ...
Aya Miyazaki, Kentaro Ishii, Satoshi Yamashita, Susumu Nejigane, Shinya Matsukawa, Yuzuru Ito, Yasuko Onuma, Makoto Asashima, Tatsuo Michiue   +8 more
doaj   +1 more source

Brachyury and SMAD signalling collaboratively orchestrate distinct mesoderm and endoderm gene regulatory networks in differentiating human embryonic stem cells

Development, 2015
The transcription factor brachyury (T, BRA) is one of the first markers of gastrulation and lineage specification in vertebrates. Despite its wide use and importance in stem cell and developmental biology, its functional genomic targets in human cells ...
Tiago Faial, A. Bernardo, Sasha Mendjan, E. Diamanti, Daniel Ortmann, George E. Gentsch, V. Mascetti, M. Trotter, James C. Smith, R. Pedersen   +9 more
semanticscholar   +1 more source

Rab7 is required for mesoderm patterning and gastrulation in Xenopus

Biology Open, 2021
Early embryogenesis requires tightly controlled temporal and spatial coordination of cellular behavior and signaling. Modulations are achieved at multiple levels, from cellular transcription to tissue-scale behavior.
Jennifer Kreis, Fee M. Wielath, Philipp Vick   +2 more
doaj   +1 more source

Ready, set, differentiate! [PDF]

, 2013
The expression of E-Cadherin, a protein best known for its role in cell adhesion, regulates the onset of embryonic ...
Rodriguez, TA, Sancho, M
core   +2 more sources