Results 101 to 110 of about 27,540 (239)
Circadian Rhythms, the Mesolimbic Dopaminergic Circuit, and Drug Addiction [PDF]
, 2007 Drug addiction is a devastating disease that affects millions of individuals worldwide. Through better understanding of the genetic variations that create a vulnerability for addiction and the molecular mechanisms that underlie the progression of ...
Colleen A. McClung
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Accumbal Dopamine Release Tracks the Expectation of Dopamine Neuron-Mediated Reinforcement
Cell Reports, 2019 Summary: Dopamine (DA) transmission in the nucleus accumbens (NAc) facilitates cue-reward associations and appetitive action. Reward-related accumbal DA release dynamics are traditionally ascribed to ventral tegmental area (VTA) DA neurons. Activation of
Dan P. Covey, Joseph F. Cheer
doaj +1 more source
Psychiatry and Clinical Neurosciences, EarlyView.Addiction is a chronic relapsing condition characterized by compulsive reward seeking and impaired behavioral control, associated with major individual and societal burden. Mechanistic investigation in humans remains constrained by ethical limitations, uncontrolled exposure histories, and ecological confounds.
Vanessa Fleury +6 more
wiley +1 more source
Dipole reconstruction as a method for identifying patients with mesolimbic epilepsy
, 1997 The aim of the study was to evaluate whether or not dipole analysis of extracranially recorded epileptiform activity, using a spherical three-shell head model, may distinguish epilepsy of mesolimbic origin from origins of other locations. Dipole analysis
Lantz, G., Ryding, E., Rosen, I.
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Clozapine's functional mesolimbic selectivity is not duplicated by the addition of anticholinergic action to haloperidol: a brain stimulation study in the rat [PDF]
, 1993 This study examined whether the anticholinergic potency of the clinically superior antipsychotic drug clozapine contributes to clozapine's anatomically-selective functional inhibition of the mesolimbic dopamine (DA) system, using an electrical brain ...
Paredes, William +2 more
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, 1993 The increase in mesolimbic dopamine (DA) release observed during the first 40 min of 120 min restraint in naive rats is not evident in repeatedly stressed animals (daily 60 min restraint, for 5 days).
CABIB, Simona +2 more
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International Journal of Methods in Psychiatric Research, Volume 35, Issue 4, December 2026.ABSTRACT Objective Smoking has been linked to both peripheral ghrelin levels and depressive symptoms. However, the association between cerebrospinal fluid (CSF) ghrelin levels and depressive symptoms, and the moderating role of smoking, remains unclear. This study aims to investigate the specific relationship among the three categories. Methods In this
Yueling Hu +10 more
wiley +1 more source
, 2018 Despite the ubiquity and importance of speeding offenses, there has been little neuroscience research regarding the propensity for speeding among vehicle drivers.
Yuji Uchiyama +3 more
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The Evolution of Motivated and Modulated Robot Selection
International Journal of Advanced Robotic Systems, 2013 In this paper we focus on the development of a selection model that allows a robot to select pre-evolved behaviour in a motivated environment. A collection task is set in an arena where the Khepera robot has to collect cylinders, which simulate food ...
Fernando Montes-Gonzalez +1 more
doaj +1 more source
Aberrant mesolimbic dopamine–opiate interaction in obesity
NeuroImage, 2015 Dopamine and opioid neurotransmitter systems share many functions such as regulation of reward and pleasure. μ-Opioid receptors (MOR) modulate the mesolimbic dopamine system in ventral tegmental area and striatum, key areas implicated in reward. We hypothesized that dopamine and opioid receptor availabilities correlate in vivo and that this correlation
Karlsson Hasse +11 more
openaire +7 more sources