Results 51 to 60 of about 14,708 (190)

Mycobacteria attenuate nociceptive responses by formyl peptide receptor triggered opioid peptide release from neutrophils. [PDF]

PLoS Pathogens, 2009
In inflammation, pain is regulated by a balance of pro- and analgesic mediators. Analgesic mediators include opioid peptides which are secreted by neutrophils at the site of inflammation, leading to activation of opioid receptors on peripheral sensory ...
Heike L Rittner, Dagmar Hackel, Philipp Voigt, Shaaban Mousa, Andrea Stolz, Dominika Labuz, Michael Schäfer, Michael Schaefer, Christoph Stein, Alexander Brack   +9 more
doaj   +1 more source

Parallel Tempering Algorithm for Conformational Studies of Biological Molecules [PDF]

, 1997
The effectiveness of a new algorithm, parallel tempering, is studied for numerical simulations of biological molecules. These molecules suffer from a rough energy landscape.
Eisenmenger, Geyer, Hansmann, Hansmann, Hansmann, Hansmann, Hansmann, Hansmann, Metropolis, Okamoto, Sipple, Swendsen, Tesi, Tsallis   +13 more
core   +3 more sources

Effects of Electroacupuncture at ST36 on Visceral Pain and Inflammatory Markers in IBS Rats

Neurogastroenterology &Motility, EarlyView.
Electroacupuncture (EA) at ST36 significantly reduced visceral pain and colonic inflammation in IBS model rats. EA increased pain thresholds, lowered AWR scores, and downregulated key inflammatory mediators (IL‐1β, IL‐6, TNF‐α, TRPV1, NF‐κB). These findings highlight ST36‐targeted EA as a promising therapeutic strategy for IBS visceral hypersensitivity
Ya‐bo Hao, Yan‐lin Liu, Xiao‐mei Wang, Kai Cheng, Qing‐yu Tu, Fei Dai, Xi‐bing Yang   +6 more
wiley   +1 more source

Neurotransmitters and putative neuromodulators in the gut of Anguilla anguilla (L.). Localizations in the enteric nervous and endocrine systems

European Journal of Histochemistry, 2009
The gut of silver eels (Anguilla anguilla L.) was investigated in order to describe both the cholinergic and adrenergic intramural innervations, and the localization of possible accessory neuromediators.
A Veggetti, F Mascarello, S Arrighi, G Radaelli, C Domeneghini   +4 more
doaj   +3 more sources

Stabilization and Reactions of Sulfur Radical Cations: Relevance to One-Electron Oxidation of Methionine in Peptides and Proteins

CHIMIA, 2008
Methionine is a key amino acid that has numerous roles in essential vital processes. Moreover, methionine oxidation is biologically important during conditions of oxidative stress and represents an important step in the development of some ...
Krzysztof Bobrowski, Chantal Houée-Levin, Bronislaw Marciniak   +2 more
doaj   +1 more source

Protective effects of Met-enkephalin on alcohol induced gastric lesions [PDF]

, 2000
The model of ethanol induced gastric lesions is useful in the evaluation of gastric cytoprotection. We used it to measure cytoprotective effects of two neuropeptides, Met-enkephalin (Peptid-M, LUPEX(R)) and alpha -melanocyte stimulating hormone (alpha ...
Alenka Boban-Blagaić, Dražen Vikić-Topić, Josip Pavan, Nikola Štambuk, Paško Konjevoda, Pero Ramadan, Smiljka Vikić-Topić, Vladimir Mrljak, Zdenko Biđin   +8 more
core   +1 more source

Multi-Overlap Simulations for Transitions between Reference Configurations

, 2003
We introduce a new procedure to construct weight factors, which flatten the probability density of the overlap with respect to some pre-defined reference configuration.
A. Mitsutake, A. Mitsutake, B. Hesselbo, B. von Freyberg, B.A. Berg, B.A. Berg, B.A. Berg, B.A. Berg, B.A. Berg, B.A. Berg, B.A. Berg, Bernd A. Berg, D. Hamada, F. Eisenmenger, F. Wang, G.M. Torrie, H. Meirovitch, Hiroshi Noguchi, K. Kuwajima, M.J. Sippl, N. Metropolis, R.A. Sayle, U.H. Hansmann, U.H. Hansmann, U.H. Hansmann, Y. Okamoto, Y. Sugita, Yuko Okamoto, Z. Li   +28 more
core   +1 more source

Two peptidases that convert ¹²⁵I‐Lys‐Arg(Met)enkephalin and ¹²⁵I‐(Met)enkephalin‐Arg⁶, respectively, to ¹²⁵I‐(Met)enkephalin in bovine adrenal medullary chromaffin granules [PDF]

FEBS Letters, 1984
Two peptidases which convert 125I‐Lys‐Arg‐ME and 125I‐ME‐Arg6, respectively, to 125I‐ME, have been identified and characterized in bovine adrenomedullary chromaffin granules. The former is referred to as a secretory granule peptidase (SGP) and the latter as a carboxypeptidase B‐like enzyme (CPB‐like) [7] which is here further characterized. SGP cleaved
Hook, Vivian Y.H., Eiden, Lee E.
openaire   +2 more sources

The effectiveness of aerobic exercise on pain and disability in individuals with neck pain: A systematic review and meta‐analysis

Experimental Physiology, EarlyView.
Abstract The present review aimed to investigate the effectiveness of aerobic exercise (AE) compared to other interventions in decreasing pain intensity and reducing disability in individuals with neck pain. A systematic review (SR) of randomized controlled trials was conducted. This SR was registered in PROSPERO (CRD42021231231).
Ana lzabela Sobral de Oliveira‐Souza, Marie Kempe, Sofia Grimmelsmann, Luiz Felipe Tavares, Ester Moreira De Castro‐Carletti, Angela Viegas Andrade, Liz Dennett, Harry Von Piekartz, Jorge Fuentes Contreras, Susan Armijo‐Olivo   +9 more
wiley   +1 more source

Elevated Prolactin during Pregnancy Drives a Phenotypic Switch in Mouse Hypothalamic Dopaminergic Neurons

Cell Reports, 2019
Summary: Altered physiological states require neuronal adaptation. In late pregnancy and lactation, a sub-population of the mouse hypothalamic tuberoinfundibular dopaminergic (TIDA) neurons alters their behavior to synthesize and release met-enkephalin ...
Siew H. Yip, Nicola Romanò, Papillon Gustafson, David J. Hodson, Eloise J. Williams, Ilona C. Kokay, Agnes O. Martin, Patrice Mollard, David R. Grattan, Stephen J. Bunn   +9 more
doaj   +1 more source