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Genetic-Metabolic Coupling for Targeted Metabolic Engineering [PDF]
Cell Reports, 2017 Summary: Production of chemicals in microbes often employs potent biosynthetic enzymes, which can interact with the microbial native metabolism to affect cell fitness and product yield.
Stefano Cardinale +2 more
doaj +8 more sources
Applied Microbiology and Biotechnology, 2001 Metabolic engineering has developed as a very powerful approach to optimising industrial fermentation processes through the introduction of directed genetic changes using recombinant DNA technology. Successful metabolic engineering starts with a careful analysis of cellular function; based on the results of this analysis, an improved strain is designed
中村 憲夫 +3 more
core +5 more sources
Analytics for metabolic engineering [PDF]
Frontiers in Bioengineering and Biotechnology, 2015 Realizing the promise of metabolic engineering has been slowed by challenges related to moving beyond proof-of-concept examples to robust and economically viable systems. Key to advancing metabolic engineering beyond trial-and-error research is access to
Christopher J Petzold +4 more
doaj +3 more sources
Metabolic engineering of Yarrowia lipolytica targeting bottlenecks to boost D-Pantothenic acid biosynthesis. [PDF]
Bioresour BioprocessLi XK +6 more
europepmc +2 more sources
CRISPR-Cas9 Gene Editing in <i>Aspergillus</i>: From Pathogenesis to Metabolic Engineering. [PDF]
Biology (Basel)Hu D, Zhao R, Lin Y, Jiang C.
europepmc +3 more sources
iScience, 2022 Summary: Bio-electrochemical systems are based on extracellular electron transfer (EET), whose efficiency relates to the expression level of numerous genes.
Yaru Chen +3 more
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Engineering Cellular Metabolism [PDF]
Cell, 2016 Metabolic engineering is the science of rewiring the metabolism of cells to enhance production of native metabolites or to endow cells with the ability to produce new products. The potential applications of such efforts are wide ranging, including the generation of fuels, chemicals, foods, feeds, and pharmaceuticals.
Nielsen, Jens, Keasling, Jay D
openaire +7 more sources
A Sustainable Chemicals Manufacturing Paradigm Using CO2 and Renewable H2
iScience, 2020 Summary: The chemical industry must decarbonize to align with UN Sustainable Development Goals. A shift toward circular economies makes CO2 an attractive feedstock for producing chemicals, provided renewable H2 is available through technologies such as ...
Rajesh Reddy Bommareddy +6 more
doaj +1 more source
METABOLIC ENGINEERING OF SOLVENTOGENIC Clostridia [PDF]
Biotechnologia Acta, 2019 Literary data on the organization of the genome, the connection of genes with the production and regulation of solvents, and the metabolic engineering of solventogenic clostridia are presented.
O. Tigunova +3 more
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