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Genetic-Metabolic Coupling for Targeted Metabolic Engineering [PDF]
Cell Reports, 2017 Summary: Production of chemicals in microbes often employs potent biosynthetic enzymes, which can interact with the microbial native metabolism to affect cell fitness and product yield.
Stefano Cardinale +2 more
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Analytics for metabolic engineering [PDF]
Frontiers in Bioengineering and Biotechnology, 2015 Realizing the promise of metabolic engineering has been slowed by challenges related to moving beyond proof-of-concept examples to robust and economically viable systems. Key to advancing metabolic engineering beyond trial-and-error research is access to
Christopher J Petzold +4 more
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Integrative metabolic engineering
AIMS Bioengineering, 2015 Recent advances in experimental and computational synthetic biology are extremely useful for achieving metabolic engineering objectives. The integration of synthetic biology and metabolic engineering within an iterative design-build-test framework will ...
George H McArthur IV +3 more
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METABOLIC ENGINEERING OF SOLVENTOGENIC Clostridia [PDF]
Biotechnologia Acta, 2019 Literary data on the organization of the genome, the connection of genes with the production and regulation of solvents, and the metabolic engineering of solventogenic clostridia are presented.
O. Tigunova +3 more
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iScience, 2022 Summary: Bio-electrochemical systems are based on extracellular electron transfer (EET), whose efficiency relates to the expression level of numerous genes.
Yaru Chen +3 more
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A Sustainable Chemicals Manufacturing Paradigm Using CO2 and Renewable H2
iScience, 2020 Summary: The chemical industry must decarbonize to align with UN Sustainable Development Goals. A shift toward circular economies makes CO2 an attractive feedstock for producing chemicals, provided renewable H2 is available through technologies such as ...
Rajesh Reddy Bommareddy +6 more
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Microbial cell factories based on filamentous bacteria, yeasts, and fungi
Microbial Cell Factories, 2023 Background Advanced DNA synthesis, biosensor assembly, and genetic circuit development in synthetic biology and metabolic engineering have reinforced the application of filamentous bacteria, yeasts, and fungi as promising chassis cells for chemical ...
Qiang Ding, Chao Ye
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Considering Strain Variation and Non-Type Strains for Yeast Metabolic Engineering Applications
Life, 2022 A variety of yeast species have been considered ideal hosts for metabolic engineering to produce value-added chemicals, including the model organism Saccharomyces cerevisiae, as well as non-conventional yeasts including Yarrowia lipolytica, Kluyveromyces
Xiunan Yi, Hal S. Alper
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The logics of metabolic regulation in bacteria challenges biosensor-based metabolic engineering
Microbial Cell, 2017 Synthetic Biology (SB) aims at the rational design and engineering of novel biological functions and systems. By facilitating the engineering of living organisms, SB promises to facilitate the development of many new applications for health ...
Matthieu Jules
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Advances in the optimization of central carbon metabolism in metabolic engineering
Microbial Cell Factories, 2023 Central carbon metabolism (CCM), including glycolysis, tricarboxylic acid cycle and the pentose phosphate pathway, is the most fundamental metabolic process in the activities of living organisms that maintains normal cellular growth.
Zhenke Wu +7 more
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