Results 1 to 10 of about 290,642 (135)

Analytics for metabolic engineering [PDF]

open access: yesFrontiers in Bioengineering and Biotechnology, 2015
Realizing the promise of metabolic engineering has been slowed by challenges related to moving beyond proof-of-concept examples to robust and economically viable systems. Key to advancing metabolic engineering beyond trial-and-error research is access to
Christopher J Petzold   +4 more
doaj   +3 more sources

Genetic-Metabolic Coupling for Targeted Metabolic Engineering [PDF]

open access: yesCell Reports, 2017
Summary: Production of chemicals in microbes often employs potent biosynthetic enzymes, which can interact with the microbial native metabolism to affect cellĀ fitness and product yield.
Stefano Cardinale   +2 more
doaj   +4 more sources

Metabolic pathway engineering

open access: yesSynthetic and Systems Biotechnology, 2018
Hal S. Alper
doaj   +3 more sources

Type I-F CRISPR-PAIR platform for multi-mode regulation to boost extracellular electron transfer in Shewanella oneidensis

open access: yesiScience, 2022
Summary: Bio-electrochemical systems are based on extracellular electron transfer (EET), whose efficiency relates to the expression level of numerous genes.
Yaru Chen   +3 more
doaj   +1 more source

Engineering Cellular Metabolism [PDF]

open access: yesCell, 2016
Metabolic engineering is the science of rewiring the metabolism of cells to enhance production of native metabolites or to endow cells with the ability to produce new products. The potential applications of such efforts are wide ranging, including the generation of fuels, chemicals, foods, feeds, and pharmaceuticals.
Nielsen, Jens, Keasling, Jay D
openaire   +7 more sources

A Sustainable Chemicals Manufacturing Paradigm Using CO2 and Renewable H2

open access: yesiScience, 2020
Summary: The chemical industry must decarbonize to align with UN Sustainable Development Goals. A shift toward circular economies makes CO2 an attractive feedstock for producing chemicals, provided renewable H2 is available through technologies such as ...
Rajesh Reddy Bommareddy   +6 more
doaj   +1 more source

METABOLIC ENGINEERING OF SOLVENTOGENIC Clostridia [PDF]

open access: yesBiotechnologia Acta, 2019
Literary data on the organization of the genome, the connection of genes with the production and regulation of solvents, and the metabolic engineering of solventogenic clostridia are presented.
O. Tigunova   +3 more
doaj   +1 more source

Microbial cell factories based on filamentous bacteria, yeasts, and fungi

open access: yesMicrobial Cell Factories, 2023
Background Advanced DNA synthesis, biosensor assembly, and genetic circuit development in synthetic biology and metabolic engineering have reinforced the application of filamentous bacteria, yeasts, and fungi as promising chassis cells for chemical ...
Qiang Ding, Chao Ye
doaj   +1 more source

Considering Strain Variation and Non-Type Strains for Yeast Metabolic Engineering Applications

open access: yesLife, 2022
A variety of yeast species have been considered ideal hosts for metabolic engineering to produce value-added chemicals, including the model organism Saccharomyces cerevisiae, as well as non-conventional yeasts including Yarrowia lipolytica, Kluyveromyces
Xiunan Yi, Hal S. Alper
doaj   +1 more source

The logics of metabolic regulation in bacteria challenges biosensor-based metabolic engineering

open access: yesMicrobial Cell, 2017
Synthetic Biology (SB) aims at the rational design and engineering of novel biological functions and systems. By facilitating the engineering of living organisms, SB promises to facilitate the development of many new applications for health ...
Matthieu Jules
doaj   +1 more source

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