Results 11 to 20 of about 3,807,237 (401)
Comprehensive Detection of Genes Causing a Phenotype using Phenotype Sequencing and Pathway Analysis [PDF]
, 2013 Discovering all the genetic causes of a phenotype is an important goal in functional genomics. In this paper we combine an experimental design for multiple independent detections of the genetic causes of a phenotype, with a high-throughput sequencing analysis that maximizes sensitivity for comprehensively identifying them.
Gronenberg, Luisa +3 more
arxiv +4 more sources
Synthetic metabolism: metabolic engineering meets enzyme design [PDF]
Current Opinion in Chemical Biology, 2017 Metabolic engineering aims at modifying the endogenous metabolic network of an organism to harness it for a useful biotechnological task, for example, production of a value-added compound. Several levels of metabolic engineering can be defined and are the topic of this review.
Erb, TJ, Jones, PR, Bar-Even, A
openaire +9 more sources
Metabolic engineering of microbial cell factories for production of nutraceuticals
Microbial Cell Factories, 2019 Metabolic engineering allows for the rewiring of basic metabolism to overproduce both native and non-native metabolites. Among these biomolecules, nutraceuticals have received considerable interest due to their health-promoting or disease-preventing ...
Shuo-Fu Yuan, Hal S. Alper
doaj +2 more sources
Biosynthetic Pathway and Metabolic Engineering of Succinic Acid
Frontiers in Bioengineering and Biotechnology, 2022 Succinic acid, a dicarboxylic acid produced as an intermediate of the tricarboxylic acid (TCA) cycle, is one of the most important platform chemicals for the production of various high value-added derivatives.
Xiutao Liu +5 more
semanticscholar +1 more source
Chemical Reviews, 2021 Since the industrial revolution, the rapid growth and development of global industries have depended largely upon the utilization of coal-derived chemicals, and more recently, the utilization of petroleum-based chemicals. These developments have followed
Pattarawan Intasian +6 more
semanticscholar +1 more source
Biotechnology for Biofuels, 2021 The issues of global warming, coupled with fossil fuel depletion, have undoubtedly led to renewed interest in other sources of commercial fuels. The search for renewable fuels has motivated research into the biological degradation of lignocellulosic ...
M. Adegboye +3 more
semanticscholar +1 more source
Metabolic Engineering of Isoflavones: An Updated Overview
Frontiers in Plant Science, 2021 Isoflavones are ecophysiologically active secondary metabolites derived from the phenylpropanoid pathway. They were mostly found in leguminous plants, especially in the pea family.
S. Sohn +5 more
semanticscholar +1 more source
Engineering Cellular Metabolism [PDF]
Cell, 2016 Metabolic engineering is the science of rewiring the metabolism of cells to enhance production of native metabolites or to endow cells with the ability to produce new products. The potential applications of such efforts are wide ranging, including the generation of fuels, chemicals, foods, feeds, and pharmaceuticals.
Jens Nielsen +3 more
openaire +7 more sources
Introduction to Metabolic Engineering Communications
Metabolic Engineering Communications, 2014 Ryan T. Gill, Vassily Hatzimanikatis
doaj +4 more sources