Results 11 to 20 of about 623,308 (344)
Integrative metabolic engineering
AIMS Bioengineering, 2015 Recent advances in experimental and computational synthetic biology are extremely useful for achieving metabolic engineering objectives. The integration of synthetic biology and metabolic engineering within an iterative design-build-test framework will ...
George H McArthur IV +3 more
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Microbial cell factories based on filamentous bacteria, yeasts, and fungi
Microbial Cell Factories, 2023 Background Advanced DNA synthesis, biosensor assembly, and genetic circuit development in synthetic biology and metabolic engineering have reinforced the application of filamentous bacteria, yeasts, and fungi as promising chassis cells for chemical ...
Qiang Ding, Chao Ye
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Considering Strain Variation and Non-Type Strains for Yeast Metabolic Engineering Applications
Life, 2022 A variety of yeast species have been considered ideal hosts for metabolic engineering to produce value-added chemicals, including the model organism Saccharomyces cerevisiae, as well as non-conventional yeasts including Yarrowia lipolytica, Kluyveromyces
Xiunan Yi, Hal S. Alper
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Plant Metabolic Engineering [PDF]
Plant Physiology, 2001 Metabolic engineering is generally defined as the redirection of one or more enzymatic reactions to produce new compounds in an organism, improve the production of existing compounds, or mediate the degradation of compounds.
openaire +2 more sources
The logics of metabolic regulation in bacteria challenges biosensor-based metabolic engineering
Microbial Cell, 2017 Synthetic Biology (SB) aims at the rational design and engineering of novel biological functions and systems. By facilitating the engineering of living organisms, SB promises to facilitate the development of many new applications for health ...
Matthieu Jules
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Advances in the optimization of central carbon metabolism in metabolic engineering
Microbial Cell Factories, 2023 Central carbon metabolism (CCM), including glycolysis, tricarboxylic acid cycle and the pentose phosphate pathway, is the most fundamental metabolic process in the activities of living organisms that maintains normal cellular growth.
Zhenke Wu +7 more
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Gene-to-metabolite network for biosynthesis of lignans in MeJA-elicited Isatis indigotica hairy root cultures. [PDF]
, 2015 Root and leaf tissue of Isatis indigotica shows notable anti-viral efficacy, and are widely used as "Banlangen" and "Daqingye" in traditional Chinese medicine.
Chen, Junfeng +9 more
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The LASER database: Formalizing design rules for metabolic engineering
Metabolic Engineering Communications, 2015 The ability of metabolic engineers to conceptualize, implement, and evaluate strain designs has dramatically increased in the last decade. Unlike other engineering fields, no centralized, open-access, and easily searched repository exists for cataloging ...
James D. Winkler +2 more
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Erythrocytes as Carriers of Therapeutic Enzymes. [PDF]
, 2020 Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to ...
Bax, BE
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Characterizing and engineering promoters for metabolic engineering of Ogataea polymorpha
Synthetic and Systems Biotechnology, 2022 Bio-manufacturing via microbial cell factory requires large promoter library for fine-tuned metabolic engineering. Ogataea polymorpha, one of the methylotrophic yeasts, possesses advantages in broad substrate spectrum, thermal-tolerance, and capacity to ...
Chunxiao Yan +6 more
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