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The logics of metabolic regulation in bacteria challenges biosensor-based metabolic engineering
Synthetic Biology (SB) aims at the rational design and engineering of novel biological functions and systems. By facilitating the engineering of living organisms, SB promises to facilitate the development of many new applications for health ...
Matthieu Jules
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β-alanine is widely used as an intermediate in industrial production. However, the low production of microbial cell factories limits its further application.
Jian Xu, Li Zhou, Zhemin Zhou
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The future of metabolic engineering and synthetic biology: Towards a systematic practice [PDF]
Industrial biotechnology promises to revolutionize conventional chemical manufacturing in the years ahead, largely owing to the excellent progress in our ability to re-engineer cellular metabolism.
De Mey, Marjan+4 more
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Expanding metabolic engineering algorithms using feasible space and shadow price constraint modules
While numerous computational methods have been developed that use genome-scale models to propose mutants for the purpose of metabolic engineering, they generally compare mutants based on a single criteria (e.g., production rate at a mutant׳s maximum ...
Christopher J. Tervo, Jennifer L. Reed
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Recent advances in bioengineering of the oleaginous yeast Yarrowia lipolytica
The oleaginous yeast, Yarrowia lipolytica, is becoming increasing popular for metabolic engineering applications. Advances in synthetic biology and metabolic engineering have allowed microorganisms such as Y.
Murtaza Shabbir Hussain+5 more
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Genetic and metabolic engineering [PDF]
Recent advances in molecular biology techniques, analytical methods and mathematical tools have led to a growing interest in using metabolic engineering to redirect metabolic fluxes for industrial and medical purposes. Metabolic engineering is referred to as the directed improvement of cellular properties through the modification of specific ...
Yea-Tyng Yang+2 more
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The Studies in Constructing Yeast Cell Factories for the Production of Fatty Acid Alkyl Esters
Fatty acid alkyl esters have broad applications in biofuels, lubricant formulas, paints, coatings, and cosmetics. Traditionally, these esters are mostly produced through unsustainable and energy-intensive processes.
Yang Zhang+4 more
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Aromatic Plants Metabolic Engineering: A Review
Secondary metabolites of aromatic plants are used in many health applications as drugs, pheromones, insecticides, fragrances, and antioxidants. Due to the huge commercial demand for these secondary metabolites, the need to overcome the insufficient ...
Olga V. Shelepova+6 more
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Metabolic network modularity arising from simple growth processes
Metabolic networks consist of linked functional components, or modules. The mechanism underlying metabolic network modularity is of great interest not only to researchers of basic science but also to those in fields of engineering.
Takemoto, Kazuhiro
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Systems Metabolic Engineering of Industrial Microorganisms
The green and sustainable production of chemicals, materials, fuels, food, and pharmaceuticals has become a key solution to the global energy and environmental crisis [...]
Xueqin Lv+3 more
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