Results 21 to 30 of about 3,807,237 (401)
Metabolic engineering of sesquiterpene metabolism in yeast [PDF]
Biotechnology and Bioengineering, 2006 AbstractTerpenes are structurally diverse compounds that are of interest because of their biological activities and industrial value. These compounds consist of chirally rich hydrocarbon backbones derived from terpene synthases, which are subsequently decorated with hydroxyl substituents catalyzed by terpene hydroxylases.
Shunji Takahashi +8 more
openaire +3 more sources
Microbial cell factories based on filamentous bacteria, yeasts, and fungi
Microbial Cell Factories, 2023 Background Advanced DNA synthesis, biosensor assembly, and genetic circuit development in synthetic biology and metabolic engineering have reinforced the application of filamentous bacteria, yeasts, and fungi as promising chassis cells for chemical ...
Qiang Ding, Chao Ye
doaj +1 more source
Metabolic engineering of Yarrowia lipolytica for terpenoids production: advances and perspectives
Critical Reviews in Biotechnology, 2021 Terpenoids are a large family of natural products with diversified structures and functions that are widely used in the food, pharmaceutical, cosmetic, and agricultural fields.
Ge Zhang +5 more
semanticscholar +1 more source
Considering Strain Variation and Non-Type Strains for Yeast Metabolic Engineering Applications
Life, 2022 A variety of yeast species have been considered ideal hosts for metabolic engineering to produce value-added chemicals, including the model organism Saccharomyces cerevisiae, as well as non-conventional yeasts including Yarrowia lipolytica, Kluyveromyces
Xiunan Yi, Hal S. Alper
doaj +1 more source
Linking intra- and extra-cellular metabolic domains via neural-network surrogates for dynamic metabolic control [PDF]
, 2023 We outline a modeling and optimization strategy for investigating dynamic metabolic engineering interventions. Our framework is particularly useful at the early stages of research and development, often constrained by limited knowledge and experimental data.
arxiv +1 more source
The virus as metabolic engineer [PDF]
Biotechnology Journal, 2010 AbstractRecent genome‐wide screens of host genetic requirements for viral infection have reemphasized the critical role of host metabolism in enabling the production of viral particles. In this review, we highlight the metabolic aspects of viral infection found in these studies, and focus on the opportunities these requirements present for metabolic ...
Miriam V. Gutschow +3 more
openaire +3 more sources
Nucleic Acids Research, 2021 The industrial yeast Pichia pastoris has been harnessed extensively for production of proteins, and it is attracting attention as a chassis cell factory for production of chemicals.
Peng Cai +5 more
semanticscholar +1 more source
Metabolic engineering of micronutrients in crop plants [PDF]
, 2016 Micronutrient deficiency is a widespread phenomenon, most prevalent in developing countries. Being causally linked to the occurrence of a range of diseases, it affects billions of people worldwide. Enhancing the content of micronutrients in crop products
Blancquaert, Dieter +3 more
core +2 more sources
Gene-to-metabolite network for biosynthesis of lignans in MeJA-elicited Isatis indigotica hairy root cultures. [PDF]
, 2015 Root and leaf tissue of Isatis indigotica shows notable anti-viral efficacy, and are widely used as "Banlangen" and "Daqingye" in traditional Chinese medicine.
Chen, Junfeng +9 more
core +2 more sources
Mass Conservation And Inference of Metabolic Networks from High-throughput Mass Spectrometry Data [PDF]
J Comput Biol, vol. 18 (2) pp. 147-54, 2011, 2010 We present a step towards the metabolome-wide computational inference of cellular metabolic reaction networks from metabolic profiling data, such as mass spectrometry. The reconstruction is based on identification of irreducible statistical interactions among the metabolite activities using the ARACNE reverse-engineering algorithm and on constraining ...
arxiv +1 more source