Results 31 to 40 of about 564,518 (330)

Reconstruction of metabolic networks from high-throughput metabolite profiling data: in silico analysis of red blood cell metabolism

open access: yes, 2007
We investigate the ability of algorithms developed for reverse engineering of transcriptional regulatory networks to reconstruct metabolic networks from high-throughput metabolite profiling data.
Barbagallo M.   +18 more
core   +1 more source

Metabolic network modularity arising from simple growth processes

open access: yes, 2012
Metabolic networks consist of linked functional components, or modules. The mechanism underlying metabolic network modularity is of great interest not only to researchers of basic science but also to those in fields of engineering.
Takemoto, Kazuhiro
core   +1 more source

Metabolic Engineering of Corynebacterium glutamicum for Methanol Metabolism [PDF]

open access: yesApplied and Environmental Microbiology, 2015
ABSTRACT Methanol is already an important carbon feedstock in the chemical industry, but it has found only limited application in biotechnological production processes. This can be mostly attributed to the inability of most microbial platform organisms to utilize methanol as a carbon and energy source.
Sabrina Witthoff   +6 more
openaire   +3 more sources

Metabolic engineering of roseoflavin-overproducing microorganisms

open access: yesMicrobial Cell Factories, 2019
Background Roseoflavin, a promising broad-spectrum antibiotic, is naturally produced by the bacteria Streptomyces davaonensis and Streptomyces cinnabarinus.
Rodrigo Mora-Lugo   +2 more
doaj   +1 more source

Systems Metabolic Engineering of Industrial Microorganisms

open access: yesMicroorganisms, 2023
The green and sustainable production of chemicals, materials, fuels, food, and pharmaceuticals has become a key solution to the global energy and environmental crisis [...]
Xueqin Lv   +3 more
doaj   +1 more source

Metabolic engineering: Use of system-level approaches and application to fuel production in Escherichia coli [PDF]

open access: yes, 2013
Metabolic engineering was formally defined more than two decades ago (Bailey, 1991) and it is now an established discipline. Metabolic engineering is generally defined as the directed improvement of product formation or cellular properties through the ...
González, Ramón
core   +2 more sources

A Sustainable Chemicals Manufacturing Paradigm Using CO2 and Renewable H2

open access: yesiScience, 2020
Summary: The chemical industry must decarbonize to align with UN Sustainable Development Goals. A shift toward circular economies makes CO2 an attractive feedstock for producing chemicals, provided renewable H2 is available through technologies such as ...
Rajesh Reddy Bommareddy   +6 more
doaj  

Evolutionary multiobjective algorithms for in silico metabolic engineering [PDF]

open access: yes, 2008
The aims of this Metabolic Engineering conference are to provide a forum for academic and industrial researchers in the field; to bring together the different scientific disciplines that contribute to the design, analysis and optimization of metabolic ...
Ferreira, E. C.   +4 more
core   +2 more sources

Dynamic metabolic control: towards precision engineering of metabolism [PDF]

open access: yesJournal of Industrial Microbiology and Biotechnology, 2018
Abstract Advances in metabolic engineering have led to the synthesis of a wide variety of valuable chemicals in microorganisms. The key to commercializing these processes is the improvement of titer, productivity, yield, and robustness.
Liu, D   +4 more
openaire   +5 more sources

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

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