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Plant cell packs: a scalable platform for recombinant protein production and metabolic engineering [PDF]
, 2019 Industrial plant biotechnology applications include the production of sustainable fuels, complex metabolites and recombinant proteins, but process development can be impaired by a lack of reliable and scalable screening methods. Here, we describe a rapid
Arfi +28 more
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Genetic and metabolic engineering [PDF]
Electronic Journal of Biotechnology, 1998 Recent advances in molecular biology techniques, analytical methods and mathematical tools have led to a growing interest in using metabolic engineering to redirect metabolic fluxes for industrial and medical purposes. Metabolic engineering is referred to as the directed improvement of cellular properties through the modification of specific ...
Yea-Tyng Yang +2 more
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Synthetic metabolons for metabolic engineering. [PDF]
, 2014 Journal ArticleResearch Support, Non-U.S. Gov'tReviewThis is a pre-copyedited, author-produced PDF of an article accepted for publication in Journal of Experimental Botany following peer review. The definitive publisher-authenticated version J. Exp. Bot.
Howard, Thomas P. +2 more
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The metabolic engine of endothelial cells [PDF]
Nature Metabolism, 2019 Endothelial cells (ECs) line the quiescent vasculature but can form new blood vessels (a process termed angiogenesis) in disease. Strategies targeting angiogenic growth factors have been clinically developed for the treatment of malignant and ocular diseases.
Falkenberg, Kim D. +3 more
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Advances on systems metabolic engineering of Bacillus subtilis as a chassis cell
Synthetic and Systems Biotechnology, 2020 The Gram-positive model bacterium Bacillus subtilis, has been broadly applied in various fields because of its low pathogenicity and strong protein secretion ability, as well as its well-developed fermentation technology. B.
Mengjie Xiang, Qian Kang, Dawei Zhang
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Aromatic Plants Metabolic Engineering: A Review
Agronomy, 2022 Secondary metabolites of aromatic plants are used in many health applications as drugs, pheromones, insecticides, fragrances, and antioxidants. Due to the huge commercial demand for these secondary metabolites, the need to overcome the insufficient ...
Olga V. Shelepova +6 more
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Metabolic network modularity arising from simple growth processes
, 2012 Metabolic networks consist of linked functional components, or modules. The mechanism underlying metabolic network modularity is of great interest not only to researchers of basic science but also to those in fields of engineering.
Takemoto, Kazuhiro
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Systems Metabolic Engineering of Industrial Microorganisms
Microorganisms, 2023 The green and sustainable production of chemicals, materials, fuels, food, and pharmaceuticals has become a key solution to the global energy and environmental crisis [...]
Xueqin Lv +3 more
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Unleashing the power of energy storage: Engineering β-oxidation pathways for polyketide production
Synthetic and Systems Biotechnology, 2020 Overproduction of polyketides has been a challenge for metabolic engineering for decades. However, recent studies have demonstrated that in both native host and heterologous host, engineering β -oxidation pathways can lead to dramatic improvement of ...
Bin Wang, Huimin Zhao
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The Studies in Constructing Yeast Cell Factories for the Production of Fatty Acid Alkyl Esters
Frontiers in Bioengineering and Biotechnology, 2022 Fatty acid alkyl esters have broad applications in biofuels, lubricant formulas, paints, coatings, and cosmetics. Traditionally, these esters are mostly produced through unsustainable and energy-intensive processes.
Yang Zhang +4 more
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