Results 31 to 40 of about 290,662 (155)
Back to the future: Why we need enzymology to build a synthetic metabolism of the future
Beilstein Journal of Organic Chemistry, 2019 Biology is turning from an analytical into a synthetic discipline. This is especially apparent in the field of metabolic engineering, where the concept of synthetic metabolism has been recently developed.
Tobias J. Erb
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Comprehensive evaluation of the capacities of microbial cell factories
Nature CommunicationsSystems metabolic engineering is facilitating the development of high-performing microbial cell factories for producing chemicals and materials. However, constructing an efficient microbial cell factory still requires exploring and selecting various host
Gi Bae Kim, Ha Rim Kim, Sang Yup Lee
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The automated Galaxy-SynBioCAD pipeline for synthetic biology design and engineering
Nature Communications, 2022 Automated design and build processes can rapidly accelerate work in synthetic biology and metabolic engineering. Here the authors present Galaxy-SynBioCAD, a toolshed for synthetic biology, metabolic engineering, and industrial biotechnology that they ...
Joan Hérisson +13 more
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Metabolic engineering of sesquiterpene metabolism in yeast [PDF]
Biotechnology and Bioengineering, 2006 AbstractTerpenes are structurally diverse compounds that are of interest because of their biological activities and industrial value. These compounds consist of chirally rich hydrocarbon backbones derived from terpene synthases, which are subsequently decorated with hydroxyl substituents catalyzed by terpene hydroxylases.
Shunji, Takahashi +8 more
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Mini-review: In vitro Metabolic Engineering for Biomanufacturing of High-value Products
Computational and Structural Biotechnology Journal, 2017 With the breakthroughs in biomolecular engineering and synthetic biology, many valuable biologically active compound and commodity chemicals have been successfully manufactured using cell-based approaches in the past decade.
Weihua Guo, Jiayuan Sheng, Xueyang Feng
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Frontiers in Bioengineering and Biotechnology, 2020 Metabolic regulation of gene expression for the microbial production of fine chemicals, such as organic acids, is an important research topic in post-genomic metabolic engineering.
Jia-Wei Li +3 more
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Genome scale engineering techniques for metabolic engineering [PDF]
Metabolic Engineering, 2015 Metabolic engineering has expanded from a focus on designs requiring a small number of genetic modifications to increasingly complex designs driven by advances in genome-scale engineering technologies. Metabolic engineering has been generally defined by the use of iterative cycles of rational genome modifications, strain analysis and characterization ...
Liu, Rongming +3 more
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Journal of Integrative Bioinformatics, 2021 Microorganisms commonly produce many high-demand industrial products like fuels, food, vitamins, and other chemicals. Microbial strains are the strains of microorganisms, which can be optimized to improve their technological properties through metabolic ...
Man Mei Yen +3 more
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Dynamic metabolic control: towards precision engineering of metabolism [PDF]
Journal of Industrial Microbiology and Biotechnology, 2018 Abstract Advances in metabolic engineering have led to the synthesis of a wide variety of valuable chemicals in microorganisms. The key to commercializing these processes is the improvement of titer, productivity, yield, and robustness.
Liu, D +4 more
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Key applications of plant metabolic engineering.
PLoS Biology, 2014 Great strides have been made in plant metabolic engineering over the last two decades, with notable success stories including Golden rice. Here, we discuss the field's progress in addressing four long-standing challenges: creating plants that satisfy ...
Warren Lau +3 more
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