Results 31 to 40 of about 3,807,237 (401)
Multiplying the efficiency and impact of biofortification through metabolic engineering
Nature Communications, 2020 Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the negative global health and socio-economic impact of hunger.
D. Van Der Straeten +14 more
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, 2022 Please click Download on the upper right corner to see the full ...
Prather, Kristala L. J.
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Global organization of metabolic fluxes in the bacterium, Escherichia coli [PDF]
Nature 427, 839-843 (2004), 2004 Cellular metabolism, the integrated interconversion of thousands of metabolic substrates through enzyme-catalyzed biochemical reactions, is the most investigated complex intercellular web of molecular interactions. While the topological organization of individual reactions into metabolic networks is increasingly well understood, the principles ...
arxiv +1 more source
Metabolic engineering of Vibrio natriegens
Essays in Biochemistry, 2021 Vibrio natriegens is emerging as a promising host for biotechnology which is basically due to the remarkable intrinsic properties such as the exceptionally high growth and substrate consumption rates.
F. Thoma, B. Blombach
semanticscholar +1 more source
Metabolic Engineering of Bacteria [PDF]
Indian Journal of Microbiology, 2011 Yield and productivity are critical for the economics and viability of a bioprocess. In metabolic engineering the main objective is the increase of a target metabolite production through genetic engineering. Metabolic engineering is the practice of optimizing genetic and regulatory processes within cells to increase the production of a certain ...
Ravi Ranjan Kumar, Satish Prasad
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Synthetic RNA Silencing of Actinorhodin Biosynthesis in Streptomyces coelicolor A3(2) [PDF]
, 2013 We demonstrate the first application of synthetic RNA gene silencers in Streptomyces coelicolor A3(2). Peptide nucleic acid and expressed antisense RNA silencers successfully inhibited actinorhodin production.
A Hesketh +43 more
core +3 more sources
The logics of metabolic regulation in bacteria challenges biosensor-based metabolic engineering
Microbial Cell, 2017 Synthetic Biology (SB) aims at the rational design and engineering of novel biological functions and systems. By facilitating the engineering of living organisms, SB promises to facilitate the development of many new applications for health ...
Matthieu Jules
doaj +1 more source
Expanding metabolic engineering algorithms using feasible space and shadow price constraint modules
Metabolic Engineering Communications, 2014 While numerous computational methods have been developed that use genome-scale models to propose mutants for the purpose of metabolic engineering, they generally compare mutants based on a single criteria (e.g., production rate at a mutant׳s maximum ...
Christopher J. Tervo, Jennifer L. Reed
doaj +1 more source
The metabolic engine of endothelial cells [PDF]
Nature Metabolism, 2019 Endothelial cells (ECs) line the quiescent vasculature but can form new blood vessels (a process termed angiogenesis) in disease. Strategies targeting angiogenic growth factors have been clinically developed for the treatment of malignant and ocular diseases.
Kim D. Falkenberg +3 more
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Recent advances in bioengineering of the oleaginous yeast Yarrowia lipolytica
AIMS Bioengineering, 2016 The oleaginous yeast, Yarrowia lipolytica, is becoming increasing popular for metabolic engineering applications. Advances in synthetic biology and metabolic engineering have allowed microorganisms such as Y.
Murtaza Shabbir Hussain +5 more
doaj +1 more source