Results 31 to 40 of about 574,220 (331)

Metabolic Engineering of Corynebacterium glutamicum for Methanol Metabolism [PDF]

Applied and Environmental Microbiology, 2015
ABSTRACT Methanol is already an important carbon feedstock in the chemical industry, but it has found only limited application in biotechnological production processes. This can be mostly attributed to the inability of most microbial platform organisms to utilize methanol as a carbon and energy source.
Sabrina Witthoff, Katja Schmitz, Sebastian Niedenführ, Katharina Nöh, Stephan Noack, Michael Bott, Jan Marienhagen   +6 more
openaire   +3 more sources

Reconstruction of metabolic networks from high-throughput metabolite profiling data: in silico analysis of red blood cell metabolism

, 2007
We investigate the ability of algorithms developed for reverse engineering of transcriptional regulatory networks to reconstruct metabolic networks from high-throughput metabolite profiling data.
Barbagallo M., Butte A.J., C. J. UNKEFER, Frenkel E., G. S. ESCOLA, Garay R., I. NEMENMAN, Jacobasch G., Katz L., Kemp G., Kirk K., M. E. WALL, Mendes P., P. J. UNKEFER, Rose I., Steinhauser D., W. S. HLAVACEK, Walser M., Wang K.   +18 more
core   +1 more source

Type I-F CRISPR-PAIR platform for multi-mode regulation to boost extracellular electron transfer in Shewanella oneidensis

iScience, 2022
Summary: Bio-electrochemical systems are based on extracellular electron transfer (EET), whose efficiency relates to the expression level of numerous genes.
Yaru Chen, Meijie Cheng, Hao Song, Yingxiu Cao   +3 more
doaj  

Evolutionary multiobjective algorithms for in silico metabolic engineering [PDF]

, 2008
The aims of this Metabolic Engineering conference are to provide a forum for academic and industrial researchers in the field; to bring together the different scientific disciplines that contribute to the design, analysis and optimization of metabolic ...
Ferreira, E. C., Maia, Paulo, Mendes, Rui, Rocha, I., Rocha, Miguel   +4 more
core   +2 more sources

Metabolic engineering of roseoflavin-overproducing microorganisms

Microbial Cell Factories, 2019
Background Roseoflavin, a promising broad-spectrum antibiotic, is naturally produced by the bacteria Streptomyces davaonensis and Streptomyces cinnabarinus.
Rodrigo Mora-Lugo, Julian Stegmüller, Matthias Mack   +2 more
doaj   +1 more source

Metabolic engineering: Use of system-level approaches and application to fuel production in Escherichia coli [PDF]

, 2013
Metabolic engineering was formally defined more than two decades ago (Bailey, 1991) and it is now an established discipline. Metabolic engineering is generally defined as the directed improvement of product formation or cellular properties through the ...
González, Ramón
core   +2 more sources

A Sustainable Chemicals Manufacturing Paradigm Using CO2 and Renewable H2

iScience, 2020
Summary: The chemical industry must decarbonize to align with UN Sustainable Development Goals. A shift toward circular economies makes CO2 an attractive feedstock for producing chemicals, provided renewable H2 is available through technologies such as ...
Rajesh Reddy Bommareddy, Yanming Wang, Nicole Pearcy, Martin Hayes, Edward Lester, Nigel P. Minton, Alex V. Conradie   +6 more
doaj  

Dynamic metabolic control: towards precision engineering of metabolism [PDF]

Journal of Industrial Microbiology and Biotechnology, 2018
Abstract Advances in metabolic engineering have led to the synthesis of a wide variety of valuable chemicals in microorganisms. The key to commercializing these processes is the improvement of titer, productivity, yield, and robustness.
Liu, D, Mannan, AA, Han, Y, Oyarzun, DA, Zhang, F   +4 more
openaire   +5 more sources

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Advances in Metabolic Engineering of Cyanobacteria for Photosynthetic Biochemical Production

Metabolites, 2015
Engineering cyanobacteria into photosynthetic microbial cell factories for the production of biochemicals and biofuels is a promising approach toward sustainability.
Martin C. Lai, Ethan I. Lan
doaj   +1 more source