Results 21 to 30 of about 282,038 (168)
Evolution of C4 photosynthesis predicted by constraint-based modelling
eLife, 2019 Constraint-based modelling (CBM) is a powerful tool for the analysis of evolutionary trajectories. Evolution, especially evolution in the distant past, is not easily accessible to laboratory experimentation.
Mary-Ann Blätke, Andrea Bräutigam
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Reaction Motifs in Metabolic Networks [PDF]
, 2005 The classic view of metabolism as a collection of metabolic pathways is being questioned with the currently available possibility of studying whole networks. Novel ways of decomposing the network into modules and motifs that could be considered as the building blocks of a network are being suggested. In this work, we introduce a new definition of motif
Vincent Lacroix +2 more
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Structure, Properties, and Function of Glycosomes in Trypanosoma cruzi
Frontiers in Cellular and Infection Microbiology, 2020 Glycosomes are peroxisome-related organelles that have been identified in kinetoplastids and diplonemids. The hallmark of glycosomes is their harboring of the majority of the glycolytic enzymes.
Wilfredo Quiñones +5 more
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High-Performance Biocomputing in Synthetic Biology–Integrated Transcriptional and Metabolic Circuits
Frontiers in Bioengineering and Biotechnology, 2019 Biocomputing uses molecular biology parts as the hardware to implement computational devices. By following pre-defined rules, often hard-coded into biological systems, these devices are able to process inputs and return outputs—thus computing information.
Angel Goñi-Moreno, Pablo I. Nikel
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Bayesian Integrative Modeling of Genome-Scale Metabolic and Regulatory Networks
Informatics, 2020 The integration of high-throughput data to build predictive computational models of cellular metabolism is a major challenge of systems biology. These models are needed to predict cellular responses to genetic and environmental perturbations.
Hanen Mhamdi +3 more
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Complex networks: the key to systems biology
Genetics and Molecular Biology, 2008 Though introduced recently, complex networks research has grown steadily because of its potential to represent, characterize and model a wide range of intricate natural systems and phenomena.
Luciano da F. Costa +2 more
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Virulence, 2019 The Gram-negative enteropathogen Yersinia pseudotuberculosis possesses a number of regulatory systems that detect cell envelope damage caused by noxious extracytoplasmic stresses.
Edvin J. Thanikkal +11 more
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Frontiers in Bioengineering and Biotechnology, 2021 An oleaginous yeast Rhodosporidium toruloides is a promising host for converting lignocellulosic biomass to bioproducts and biofuels. In this work, we performed multi-omics analysis of lignocellulosic carbon utilization in R. toruloides and reconstructed
Joonhoon Kim +30 more
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Evolution of metabolic network organization [PDF]
BMC Systems Biology, 2010 Comparison of metabolic networks across species is a key to understanding how evolutionary pressures shape these networks. By selecting taxa representative of different lineages or lifestyles and using a comprehensive set of descriptors of the structure and complexity of their metabolic networks, one can highlight both qualitative and quantitative ...
Aurélien Mazurie +3 more
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Frontiers in Environmental Science, 2018 Determining how microbial communities organize and function at the ecosystem level is essential to understanding and predicting how they will respond to environmental change.
Joseph J. Vallino, Julie A. Huber
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