Results 41 to 50 of about 282,038 (168)
Frontiers in Applied Mathematics and Statistics, 2019 Metabolic networks have been used to successfully predict phenotypes based on optimization principles. However, a general framework that would extend to situations not governed by simple optimization, such as multispecies communities, is still lacking ...
Taneli Pusa +6 more
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Building Mathematical Models of Biological Systems with modelbase
Journal of Open Research Software, 2018 The modelbase package is a free expandable Python package for building and analysing dynamic mathematical models of biological systems. Originally it was designed for the simulation of metabolic systems, but it can be used for virtually any deterministic
Oliver Ebenhöh +4 more
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Metabolites, 2018 The use of mass spectrometry-based metabolomics to study human, plant and microbial biochemistry and their interactions with the environment largely depends on the ability to annotate metabolite structures by matching mass spectral features of the ...
Clément Frainay +6 more
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Age-Related Changes in Topological Properties of Individual Brain Metabolic Networks in Rats
Frontiers in Aging Neuroscience, 2022 Normal aging causes profound changes of structural degeneration and glucose hypometabolism in the human brain, even in the absence of disease. In recent years, with the extensive exploration of the topological characteristics of the human brain, related ...
Xin Xue +18 more
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Control of fluxes in metabolic networks [PDF]
Genome Research, 2016 Understanding the control of large-scale metabolic networks is central to biology and medicine. However, existing approaches either require specifying a cellular objective or can only be used for small networks. We introduce new coupling types describing the relations between reaction activities, and develop an efficient computational framework, which ...
Basler, Georg +4 more
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Journal of FungiEdible fungi, a group of globally significant macrofungi, are highly valued for their unique flavors and substantial nutritional and medicinal properties.
Muyun Xie +6 more
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On Functional Module Detection in Metabolic Networks
Metabolites, 2013 Functional modules of metabolic networks are essential for understanding the metabolism of an organism as a whole. With the vast amount of experimental data and the construction of complex and large-scale, often genome-wide, models, the computer-aided ...
Ina Koch, Jörg Ackermann
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Metabolic network changes during skotomorphogenesis in Arabidopsis thaliana mutant (atdfb‐3)
Plant Direct, 2022 The metabolic networks underlying skotomorphogenesis in seedlings remain relatively unknown. On the basis of our previous study on the folate metabolism in seedlings grown in darkness, the plastidial folylpolyglutamate synthetase gene (AtDFB) T‐DNA ...
Xingjuan Li +4 more
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Metabolic Network Analysis Demystified [PDF]
, 2011 Metabolic networks are a representation of current knowledge about the metabolic reactions available to a given organism. These networks can be placed into various mathematical frameworks, of which the constraintbased framework [1] has received the most attention over the past 15 years. This results in a predictive model of metabolism. Metabolic models
Leonid Chindelevitch +2 more
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Estrogen Receptors and the Metabolic Network [PDF]
Cell Metabolism, 2011 The metabolic syndrome has reached pandemic level worldwide, and evidence is that estradiol plays a key role in its development. The discovery of the second estrogen receptor, ERβ, in tissues previously not considered targets of estradiol was a breakthrough in endocrinology.
Barros, Rodrigo P.A. +1 more
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