Results 41 to 50 of about 297,984 (312)

TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei. [PDF]

, 2014
The metabolic network of a cell represents the catabolic and anabolic reactions that interconvert small molecules (metabolites) through the activity of enzymes, transporters and non-catalyzed chemical reactions.
Opperdoes, F.R. (Fred), van Hellemond, JJ, de Koning, HP, Nes, D. W.,, Nayak, A.,, Silva-Franco, F.,, de, Koning HP, Wyllie, S, Ebikeme, C., van Hellemond, Jaap; id_orcid, van Hellemond, J. J.,, Crouch, Kathryn, Ferguson, Michael A.J., Nolan, D. P.,, Bütikofer, P. (Peter), Nolan, Derek P., Barrett, Michael P, Ebikeme, C. (Charles), Olsen, C, De Koning, H.P. (Harry P.), Jourdan, F., Vinson, F. (Florence), Bütikofer, P, Ferguson, MA, Ferguson, Michael A. J., Mäser, P, Butikofer, P., Opperdoes, F. R., Breitling, R., Nayak, A, Achcar, F., Smith, Terry K., Ferguson, MAJ, Boshart, M., Boshart, M, Denise, H., Logan-Klumpler, F. J.,, Cattanach, A. M.,, Taylor, M. C., Wyllie, S. (Susan), Hertz-Fowler, C., Creek, D.J. (Darren J.), Silva-Franco, F, Nes, DW, LS Biochemie van parasieten, Smith, TK, Kerkhoven, E. J., Crouch, K, Wyllie, S., Merlet, B.,, Vincent, Isabel M., Olsen, C., Tielens, A.G.M. (Lodewijk), Regenerative Medicine, Stem Cells & Cancer, Merlet, Benjamin, Taylor, M. C.,, Cottret, L., Creek, DJ, Opperdoes, FR, Ferguson, Michael AJ, Berriman, M, Opperdoes, Fred R., Logan-Klumpler, FJ, Achcar, Fiona, Barrett, M. P., Breitling, R, Urbaniak, Michael D., Denise, H. (Hubert), Fairlamb, Alan H, Merlet, B, Boshart, Michael, Fairlamb, A. H.,, Wilkinson, SR, Taylor, MC, Urbaniak, Michael D, Crouch, K.,, Breitling, R.,, Vincent, I.M. (Isabel M.), Tielens, Aloysius G M, Breitling, R. (Rainer), Boshart, M. (Michael), de Koning, Harry P, Smith, T. K.,, Michels, PA, de Koning, H. P.,, Nes, David W., Ginger, ML, Butikofer, P.,, Barrett, M. P.,, Hertz-Fowler, Christiane, Bannerman-Chukualim, B., Hertz-Fowler, C.,, Fairlamb, Alan H., Ebikeme, C, Michels, Paul A. M., Tielens, A. G. M., Taylor, Martin C, Nolan, Derek P, Maeser, P, Boshart, M.,, Taylor, Martin C., Hertz-Fowler, C, Nayak, A. (Archana), Shameer, Sanu, Ferguson, M. A. J.,, Tielens, Aloysius G.M., Cattanach, Amy M., Crouch, K., Fairlamb, Alan H.; id_orcid, Urbaniak, MD, Tielens, Lodewijk, Jourdan, F, Ferguson, Michael A. J.; id_orcid, Berriman, M., Bringaud, Frédéric, Bannerman-Chukualim, B. (Bridget), Wyllie, S.,, Silva-Franco, F. (Fatima), Wilkinson, S. R., Silva-Franco, F., Shameer, S, Bringaud, F. (Frédéric), Bannerman-Chukualim, Bridget, Michels, Paul A.M., Ginger, M. L.,, Nes, David W, Shameer, S.,, van Hellemond, Jaap J., Ferguson, M. A. J., van Hellemond, J. J., Urbaniak, M.D. (Michael D.), Nolan, D.P. (Derek P.), Wilkinson, S. R.,, Creek, Darren J., Merlet, B., Mäser, Pascal, Michels, Paul AM, Cattanach, A.M. (Amy M.), Tielens, AG, Barrett, Michael P., Jourdan, Fabien, Wyllie, Susan, Fairlamb, AH, Bringaud, F.,, Kerkhoven, Eduard J, Maeser, Pascal, Vinson, F., Bringaud, F., Creek, D. J., Berriman, M. (Matthew), Tielens, AGM, Logan-Klumpler, Flora J, Shameer, S. (Sanu), Achcar, F.,, Michels, P. A. M., Koning, Harry P. de, Logan-Klumpler, F. J., Fairlamb, A. H., Vincent, IM, Nayak, A., Logan-Klumpler, Flora J., Bütikofer, Peter, Shameer, S., Olsen, C. (Christian), Cottret, Ludovic, Ebikeme, Charles, Cottret, L.,, Nolan, DP, Michels, PAM, Tielens, A. G. M.,, Opperdoes, F. R.,, Silva-Franco, Fatima, Kerkhoven, E.J. (Eduard), Berriman, M.,, Maser, P.,, van Hellemond, Jaap J, Urbaniak, M. D., Ginger, M.L. (Michael L.), Michels, P.A.M. (Paul), Kerkhoven, EJ, Creek, D. J.,, Maser, P., Mäser, P. (Pascal), Kerkhoven, Eduard J., Merlet, B. (Benjamin), Fairlamb, A.H. (Alan H.), Achcar, F. (Fiona), Smith, T.K. (Terry K.), de Koning, H. P., Urbaniak, M. D.,, Nes, D. (DavidW.), Crouch, K. (Kathryn), Denise, H, Bannerman-Chukualim, B.,, Jourdan, F. (Fabien), Ginger, M. L., Berriman, Matthew, Tielens, Aloysius GM, Jourdan, F.,, Achcar, F, Ebikeme, C.,, Olsen, Christian, Wilkinson, Shane R, Cottret, L. (Ludovic), Hertz-Fowler, C. (Christiane), Hellemond, Jaap J. van, Kerkhoven, Eduard,, Ginger, Michael L., Ferguson, M.A.J. (Michael A. J.), Cottret, L, Vincent, I. M., Nes, D. W., Barrett, MP, de Koning, Harry P., Michels, P. A. M.,, Cattanach, Amy M, Cattanach, AM, Hellemond, J.J. (Jaap) van, Michels, Paul A M, Nolan, D. P., Wilkinson, S.R. (Shane R.), Vinson, F.,, Wilkinson, Shane R., Breitling, Rainer, Creek, Darren J, Barrett, M.P. (Michael P.), B&C BRC-SIB-TR, Tielens, Lodewijk; id_orcid, Vinson, Florence, Tielens, Aloysius G. M., Bringaud, F, Vincent, Isabel M, Logan-Klumpler, F.J. (Flora J.), Opperdoes, Fred R, Denise, H.,, Vincent, I. M.,, Olsen, C.,, van, Hellemond JJ, Ginger, Michael L, Kerkhoven, Eduard, Denise, Hubert, Smith, T. K., Taylor, M.C. (Martin C.), Vinson, F, Nayak, Archana, Ferguson, Michael A J, van Hellemond, Jaap, Smith, Terry K, Bannerman-Chukualim, B, Cattanach, A. M.   +249 more
core   +1 more source

Local and global modes of drug action in biochemical networks [PDF]

, 2008
It becomes increasingly accepted that a shift is needed from the traditional target-based approach of drug development to an integrated perspective of drug action in biochemical systems. We here present an integrative analysis of the interactions between
Schwartz, Jean Marc; id_orcid, Jean-Marc Schwartz, Nacher, Jose C., Jose C. Nacher, Jose C Nacher   +4 more
core   +2 more sources

Using Maximum Entropy Production to Describe Microbial Biogeochemistry Over Time and Space in a Meromictic Pond

Frontiers in Environmental Science, 2018
Determining how microbial communities organize and function at the ecosystem level is essential to understanding and predicting how they will respond to environmental change.
Joseph J. Vallino, Julie A. Huber
doaj   +1 more source

Flux Coupling and the Objective Functions’ Length in EFMs

Metabolites, 2020
Structural analysis of constraint-based metabolic network models attempts to find the network’s properties by searching for subsets of suitable modes or Elementary Flux Modes (EFMs).
Francisco Guil, José F. Hidalgo, José M. García   +2 more
doaj   +1 more source

Analysis of Microbial Functions in the Rhizosphere Using a Metabolic-Network Based Framework for Metagenomics Interpretation

Frontiers in Microbiology, 2017
Advances in metagenomics enable high resolution description of complex bacterial communities in their natural environments. Consequently, conceptual approaches for community level functional analysis are in high need. Here, we introduce a framework for a
Shany Ofaim, Shany Ofaim, Maya Ofek-Lalzar, Noa Sela, Jiandong Jinag, Yechezkel Kashi, Dror Minz, Shiri Freilich   +7 more
doaj   +1 more source

Returnability in complex directed networks (digraphs) [PDF]

, 2008
The concept of returnability is proposed for complex directed networks (digraphs). It can be seen as a generalization of the concept of reciprocity. Two measures of the returnability are introduced. We establish closed formulas for the calculation of the
Estrada, Ernesto, Estrada, E., Hatano, Naomichi, Hatano, N., Ernesto Estrada, Naomichi Hatano   +5 more
core   +1 more source

A Protocol for Generating and Exchanging (Genome-Scale) Metabolic Resource Allocation Models

Metabolites, 2017
In this article, we present a protocol for generating a complete (genome-scale) metabolic resource allocation model, as well as a proposal for how to represent such models in the systems biology markup language (SBML). Such models are used to investigate
Alexandra-M. Reimers, Henning Lindhorst, Steffen Waldherr   +2 more
doaj   +1 more source

Totoro: Identifying Active Reactions During the Transient State for Metabolic Perturbations

Frontiers in Genetics, 2022
Motivation: The increasing availability of metabolomic data and their analysis are improving the understanding of cellular mechanisms and how biological systems respond to different perturbations.
Mariana Galvão Ferrarini, Mariana Galvão Ferrarini, Irene Ziska, Irene Ziska, Ricardo Andrade, Ricardo Andrade, Alice Julien-Laferrière, Louis Duchemin, Roberto Marcondes César, Arnaud Mary, Arnaud Mary, Susana Vinga, Marie-France Sagot, Marie-France Sagot   +13 more
doaj   +1 more source

Chemical screens for particle-induced macrophage death identifies kinase inhibitors of phagocytosis as targets for toxicity

Journal of Nanobiotechnology
Background Nanoparticles are increasingly being used in medicine, cosmetics, food, and manufacturing. However, potential toxicity may limit the use of newly engineered nanoparticles.
Uyen Thi Tran, Toshimori Kitami
doaj   +1 more source

Recruitment: A Problem of Entangled Temporal Parts

Frontiers in Bioscience-Landmark, 2022
Recruitment is a pervasive activity of life that is at the center of novelty generation and persistence. Without recruitment, novelties cannot spread and biological systems cannot maintain identity through time.
Gustavo Caetano-Anollés, M. Fayez Aziz, Fizza Mughal, Ibrahim Koç, Kelsey Caetano-Anollés, Derek Caetano-Anollés   +5 more
doaj   +1 more source