The Metabolic Phenotype of Prostate Cancer
Frontiers in Oncology, 2017 Prostate cancer is the most common non-cutaneous cancer in men in the United States. Cancer metabolism has emerged as a contemporary topic of great interest for improved mechanistic understanding of tumorigenesis.
Eric Eidelman +5 more
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On functional module detection in metabolic networks [PDF]
, 2013 Functional modules of metabolic networks are essential for understanding the metabolism of an organism as a whole. With the vast amount of experimental data and the construction of complex and large-scale, often genome-wide, models, the computer-aided ...
Adleman +29 more
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VitisCyc: A metabolic pathway knowledgebase for grapevine (Vitis vinifera)
Frontiers in Plant Science, 2014 We have developed VitisCyc, a grapevine-specific metabolic pathway database that allows researchers to i) search and browse the database for its various components such as metabolic pathways, reactions, compounds, genes and proteins, ii) compare ...
Sushma eNaithani +6 more
doaj +1 more source
MetaboCraft: building a Minecraft plugin for metabolomics [PDF]
, 2018 Motivation: The rapid advances in metabolomics pose a significant challenge in presentation and interpretation of results. Development of new, engaging visual aids is crucial to advancing our understanding of new findings. Results: We have developed
Burgess, Karl +2 more
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Exploring metabolic pathway disruption in the subchronic phencyclidine model of schizophrenia with the generalized singular value decomposition [PDF]
, 2011 The quantification of experimentally-induced alterations in biological pathways remains a major challenge in systems biology. One example of this is the quantitative characterization of alterations in defined, established metabolic pathways from complex ...
Dawson, Neil +6 more
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Reconstruction of metabolic pathways by combining probabilistic graphical model-based and knowledge-based methods [PDF]
, 2014 Automatic reconstruction of metabolic pathways for an organism from genomics and transcriptomics data has been a challenging and important problem in bioinformatics.
Jianlin Cheng, Jilong Li, Qi Qi
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Observing local and global properties of metabolic pathways: ‘load points’ and ‘choke points’ in the metabolic networks [PDF]
Bioinformatics, 2006 Abstract Motivation: The local and global aspects of metabolic network analyses allow us to identify enzymes or reactions that are crucial for the survival of the organism(s), therefore directing us towards the discovery of potential drug targets.
Syed Asad, Rahman, Dietmar, Schomburg
openaire +2 more sources
Deciphering rice metabolic flux reprograming under salinity stress via in silico metabolic modeling
Computational and Structural Biotechnology Journal, 2020 Rice is one of the most economically important commodities globally. However, rice plants are salt susceptible species in which high salinity can significantly constrain its productivity. Several physiological parameters in adaptation to salt stress have
Kwanjeera Wanichthanarak +5 more
doaj +1 more source
Genome-Wide Association Study of Metabolic Syndrome in Koreans [PDF]
Genomics & Informatics, 2014 Metabolic syndrome (METS) is a disorder of energy utilization and storage and increases the risk of developing cardiovascular disease and diabetes. To identify the genetic risk factors of METS, we carried out a genome-wide association study (GWAS) for 2 ...
Seok Won Jeong +4 more
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Mathematical problems for complex networks [PDF]
, 2012 Copyright @ 2012 Zidong Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited ...
Liang, J, Liu, Y, Wang, Z
core +2 more sources