Results 11 to 20 of about 3,241,184 (308)
Metabolic Pathways of Acylcarnitine Synthesis [PDF]
Acylcarnitines are important markers in metabolic studies of many diseases, including metabolic, cardiovascular, and neurological disorders. We reviewed analytical methods for analyzing acylcarnitines with respect to the available molecular structural information, the technical limitations of legacy methods, and the potential of new mass spectrometry ...
Jana Brejchova +2 more
openaire +4 more sources
Alignment of metabolic pathways [PDF]
Several genome-scale efforts are underway to reconstruct metabolic networks for a variety of organisms. As the resulting data accumulates, the need for analysis tools increases. A notable requirement is a pathway alignment finder that enables both the detection of conserved metabolic pathways among different species as well as divergent metabolic ...
Ron Y. Pinter +3 more
openaire +3 more sources
Metabolic regulation of regulatory T cell development and function [PDF]
It is now well established that the effector T cell (Teff) response is regulated by a series of metabolic switches. Quiescent T cells predominantly require ATP-generating processes, whereas proliferating Teff require high metabolic flux through growth ...
Marelli-Berg, F +7 more
core +1 more source
Phytochemicals Target Multiple Metabolic Pathways in Cancer. [PDF]
Cancer metabolic reprogramming is a complex process that provides malignant cells with selective advantages to grow and propagate in the hostile environment created by the immune surveillance of the human organism.
Kirdeeva, Yulia +13 more
core +2 more sources
Alignment of Linear Biochemical Pathways Using Protein Structural Classification [PDF]
Metabolic, signaling and regulatory pathways form the basis of biological processes and are important for the analysis of cellular behavior and evolution.
Timm Oberwahrenbrock +9 more
core +1 more source
MultiMetEval: comparative and multi-objective analysis of genome-scale metabolic models [PDF]
Comparative metabolic modelling is emerging as a novel field, supported by the development of reliable and standardized approaches for constructing genome-scale metabolic models in high throughput.
Kierzek, A.M. +37 more
core +2 more sources
HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury
Background In muscular dystrophy and old age, skeletal muscle repair is compromised leading to fibrosis and fatty tissue accumulation. Therefore, therapies that protect skeletal muscle or enhance repair would be valuable medical treatments.
Andrew N. Billin +18 more
doaj +1 more source
Background Ninety-seven independent single nucleotide polymorphisms (SNPs) are robustly associated with adult body mass index (BMI kg/m2) in Caucasian populations.
Richard J. Munthali +7 more
doaj +1 more source

