Results 31 to 40 of about 3,241,184 (308)

Algorithmic Annotation of Functional Roles for Components of 3,044 Human Molecular Pathways

open access: yesFrontiers in Genetics, 2021
Current methods of high-throughput molecular and genomic analyses enabled to reconstruct thousands of human molecular pathways. Knowledge of molecular pathways structure and architecture taken along with the gene expression data can help interrogating ...
Maxim Sorokin   +12 more
doaj   +1 more source

Evolution of Dominance in Metabolic Pathways [PDF]

open access: yesGenetics, 2004
AbstractDominance is a form of phenotypic robustness to mutations. Understanding how such robustness can evolve provides a window into how the relation between genotype and phenotype can evolve. As such, the issue of dominance evolution is a question about the evolution of inheritance systems.
Bagheri, H., Wagner, G.
openaire   +3 more sources

Restoring a Metabolic Pathway [PDF]

open access: yesACS Chemical Biology, 2008
Gluconeogenesis is blocked in a strain of Escherichia coli that is deficient in triosephosphate isomerase, but it was restored by the insertion of a plasmid coding for an L-glyceraldehyde 3-phosphate reductase (YghZ). This reductase provides a "bypass" that produces dihydroxyacetone phosphate (DHAP) by the consecutive enzyme-catalyzed reduction of L ...
openaire   +2 more sources

Asparagine Metabolic Pathways in Arabidopsis [PDF]

open access: yesPlant and Cell Physiology, 2015
Inorganic nitrogen in the form of ammonium is assimilated into asparagine via multiple steps involving glutamine synthetase (GS), glutamate synthase (GOGAT), aspartate aminotransferase (AspAT) and asparagine synthetase (AS) in Arabidopsis. The asparagine amide group is liberated by the reaction catalyzed by asparaginase (ASPG) and also the amino group ...
Gaufichon, Laure   +2 more
openaire   +4 more sources

Computational Metabolomics Operations at BioCyc.org

open access: yesMetabolites, 2015
BioCyc.org is a genome and metabolic pathway web portal covering 5500 organisms, including Homo sapiens, Arabidopsis thaliana, Saccharomyces cerevisiae and Escherichia coli.
Peter D. Karp   +7 more
doaj   +1 more source

Library of Apicomplexan Metabolic Pathways: a manually curated database for metabolic pathways of apicomplexan parasites. [PDF]

open access: yes, 2012
The Library of Apicomplexan Metabolic Pathways (LAMP, http://www.llamp.net) is a web database that provides near complete mapping from genes to the central metabolic functions for some of the prominent intracellular parasites of the phylum Apicomplexa ...
Wastling
core   +1 more source

Pathways Newsletter 2 [PDF]

open access: yes, 2013
Pathways Newsletter 2 provides a brief summary of causal inference, together with information about Pathways courses and events for 2012 ...
Miller, Sarah
core   +2 more sources

Integrative metabolomics as emerging tool to study autophagy regulation

open access: yesMicrobial Cell, 2017
Recent technological developments in metabolomics research have enabled in-depth characterization of complex metabolite mixtures in a wide range of biological, biomedical, environmental, agricultural, and nutritional research fields.
Sarah Stryeck   +2 more
doaj   +1 more source

Pathway analysis of NAD+ metabolism [PDF]

open access: yesBiochemical Journal, 2011
NAD+ is well known as a crucial cofactor in the redox balance of metabolism. Moreover, NAD+ is degraded in ADP-ribosyl transfer reactions, which are important components of multitudinous signalling reactions. These include reactions linked to DNA repair and aging.
de Figueiredo, Luis F.   +3 more
openaire   +3 more sources

Metabolic Pathways and Targets in Chondrosarcoma

open access: yesFrontiers in Oncology, 2021
Chondrosarcomas are the second most common primary bone malignancy. Chondrosarcomas are characterized by the production of cartilaginous matrix and are generally resistant to radiation and chemotherapy and the outcomes are overall poor.
Ida Micaily   +4 more
doaj   +1 more source

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