Results 271 to 280 of about 192,395 (356)

Correction: Metabolic reprogramming and M2 macrophage depletion define the microenvironment of adenomyosis. [PDF]

Front Endocrinol (Lausanne)
Frontiers Production Office.
europepmc   +1 more source

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

Advanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang, Meng Teng, Wenxuan He, Lanzhou Li, Yongfeng Zhang, Shimiao Wang, Chunyue Wang, Di Wang   +7 more
wiley   +1 more source

Editorial: Metabolic reprogramming in cancer

Frontiers in Pharmacology
Valentina Audrito, Elisa Giovannetti, Elisa Giovannetti   +2 more
openaire   +3 more sources

Engineered Bacteria Factory Integrating Drug Delivery and Antibody Manufacture for Activating the STING Signal Pathway Mediated Tumor Immunotherapy

Advanced Science, EarlyView.
To address the limitations of protein‐based ICIs in applications, this study constructed an engineered bacterium, HRB, capable of expressing aCD47 in hypoxic TME. Through the Schiff base reaction, responsive liposomes (LC) loaded with the STING agonist cGAMP were connected to the surface of bacteria to form HRB@LC.
Peng‐Shuo Dong, Tian Yao, Yong Li, Zi‐Hui Yan, Xiao‐Ting Xie, Jia‐Hua Zou, Kai Cheng, Jin‐Xuan Fan, Yuan‐Di Zhao, Qiu‐Ran Xu   +9 more
wiley   +1 more source

Mechanisms of metabolic reprogramming in abdominal aortic aneurysm. [PDF]

Front Cell Dev Biol
Wu X, Li J, Ju Q, Zeng Y, Cao J.
europepmc   +1 more source

Fig. S1 from Metabolic Reprogramming Is an Initial Step in Pancreatic Carcinogenesis That Can Be Targeted to Inhibit Acinar-to-Ductal Metaplasia

Thorsten Neuß, Min-Chun Chen, Nils Wirges, Sinem Usluer, Rupert Oellinger, Svenja Lier, Michael Dudek, Tobias Madl, Martin Jastroch, Katja Steiger, Werner Schmitz, Henrik Einwächter, Roland M. Schmid   +12 more
openalex   +1 more source

The critical role of glutamine and fatty acids in the metabolic reprogramming of anoikis-resistant melanoma cells [PDF]

Silvia Peppicelli, T. Kersikla, Giulio Menegazzi, Elena Andreucci, Jessica Ruzzolini, Chiara Nediani, Francesca Bianchini, Lido Calorini   +7 more
openalex   +1 more source

A Radioresistant‐Tumor‐Targeted Nanoparticle for X‐Ray‐Controlled Nitric Oxide Release to Potentiate Radiotherapy

Advanced Science, EarlyView.
The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang, Xiaoyan Yin, Ting Wang, Hongfu Zhao, Zhipeng Zhao, Jinbao Wang, Cheng Tao, Xuanchu Ge, Yanze Li, Linlin Liu, Fuxin Xue   +10 more
wiley   +1 more source

Bioinformatics Analysis of Genes Associated with Autophagy and Metabolic Reprogramming in Atrial Fibrillation. [PDF]

J Cardiovasc Dev Dis
Niu Y, Ihara K, Iwamiya S, Sasano T.
europepmc   +1 more source

CGF induces ROS-mediated metabolic reprogramming and mitochondrial dysfunction to suppress colorectal cancer progression

Jiebang Jiang, Xinxin Zhang, Yipeng Sun, Jin Chen, Bo Yuan, Xincheng Li, Xi Chen, Xin Chen, Rongpeng Li   +8 more
openalex   +1 more source