Results 261 to 270 of about 639,967 (307)
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Acta Anaesthesiologica Scandinavica, 1997
Morphine is a potent opioid analgesic widely used for the treatment of acute pain and for long‐term treatment of severe pain. Morphine is a member of the morphinan‐framed alkaloids, which are present in the poppy plant. The drug is soluble in water, but its solubility in lipids is poor.In man, morphine‐3‐glucuronide (M3G) and morphine‐6‐glucu‐ronide ...
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Morphine is a potent opioid analgesic widely used for the treatment of acute pain and for long‐term treatment of severe pain. Morphine is a member of the morphinan‐framed alkaloids, which are present in the poppy plant. The drug is soluble in water, but its solubility in lipids is poor.In man, morphine‐3‐glucuronide (M3G) and morphine‐6‐glucu‐ronide ...
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Mexiletine Metabolites: A Review
Current Medicinal Chemistry, 2015Mexiletine belongs to class IB antiarrhythmic drugs and it is still considered a drug of choice for treating myotonias. However some patients do not respond to mexiletine or have significant side effects limiting its use; thus, alternatives to this drug should be envisaged.
Catalano A., Carocci A., Sinicropi M. S.
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Metabolites, enzymes, and metabolite analogues
1973The smallest change in the chemical constitution of a selectively toxic agent often makes an enormous change in its biological activity, and many examples of this have been given in Chapter 2. The present chapter deals in greater detail with one cause of high specificity, namely a close resemblance between (a) the normal substrate (or coenzyme) of an ...
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The Biosynthesis of Shikimate Metabolites
ChemInform, 1999AbstractFor Abstract see ChemInform Abstract in Full Text.
Andrew R. Knaggs +2 more
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Advances in Metabolite Identification
Bioanalysis, 2011One of the central challenges to metabolomics is metabolite identification. Regardless of whether one uses so-called 'targeted' or 'untargeted' metabolomics, eventually all paths lead to the requirement of identifying (and quantifying) certain key metabolites.
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Monitoring Metabolites Using an NAD(P)H-sensitive Polymer Dot and a Metabolite-Specific Enzyme
Angewandte Chemie - International Edition, 2021Jiangbo Yu, Changfeng Wu, Jicheng Zhang
exaly

