Results 41 to 50 of about 58,396 (229)

Molecular characterization ofbla_IMP-5, a new integron-borne metallo-β-lactamase gene from anAcinetobacter baumanniinosocomial isolate in Portugal [PDF]

FEMS Microbiology Letters, 2002
Acinetobacter baumannii 65FFC, an imipenem-resistant clinical strain, isolated from the urine of a patient at the Coimbra University Hospital, Portugal, in 1998, produced a metallo-beta-lactamase with a calculated pI 9.3. The isolate was highly resistant to penicillins, broad-spectrum cephalosporins, including ceftazidime, ceftriaxone, cefepime ...
Da Silva, GJ, Correia, M, Vital, C, Ribeiro, G, Sousa, JC, Leitao, R, Peixe, L, Duarte, A   +7 more
openaire   +3 more sources

Phenotypic Characterization of Multidrug-resistant Escherichia Coli with Special Reference to Extended-spectrum-beta-lactamases and Metallo-beta-lactamases in a Tertiary Care Center

Journal of Nepal Medical Association, 2015
Introduction: The increasing reports on extended-spectrum-beta-lactamase and metallo-betalactamase producing Escherichia coli have addressed a potential threat to global health since it is found to be highly resistance to most of the currently available ...
Basudha Shrestha, Shovita Shrestha, Shyam Kumar Mishra, Hari Prasad Kattel, Tatsuya Tada, Hiroshi Ohara, Teruo Kirikae, Basista Prasad Rijal, Jeevan Bahadur Sherchand, Bharat Mani Pokhrel   +9 more
doaj   +3 more sources

Presence of VIM-positive pseudomonas species in chickens and their surrounding environment [PDF]

, 2017
Metallo-β-lactamase gene blaVIM was identified on the chromosome of four Pseudomonas sp. isolates from a chicken farm, including one Pseudomonas aeruginosa isolate from a swallow (Yanornis martini), one Pseudomonas putida isolate from a fly, and two P ...
Lei, Lei, Li, Jiyun, Li, Mei, Liu, Zhihai, Walsh, Timothy Rutland, Wang, Shaolin, Wang, Yang, Wu, Congming, Wu, Yongning, Yin, Wenjuan, Zhang, Rongmin   +10 more
core   +1 more source

First case of New Delhi metallo-β-lactamase in Klebsiella pneumoniae from Ecuador: An update for South America [PDF]

International Journal of Infectious Diseases, 2017
To describe a clinical case of Klebsiella pneumoniae harboring a New Delhi metallo-β-lactamase (NDM) plasmid in Ecuador and to present a map of reports of NDM isolates in South America.The modified Hodge test, carbapenem inactivation method, imipenem-EDTA disk method (synergy), and Rapidec Carba NP test were used to identify antibiotic resistance ...
Daniel Romero-Alvarez, Jorge Reyes, Viviana Quezada, Carolina Satán, Nelson Cevallos, Sofía Barrera, Gabriel Trueba, Luis E. Escobar, José E. Villacís   +8 more
openaire   +3 more sources

The antimicrobial peptide thanatin disrupts the bacterial outer membrane and inactivates the NDM-1 metallo-β-lactamase

Nature Communications, 2019
New Delhi metallo-β-lactamase-1 (NDM-1) is the most prevalent type of metallo-β-lactamase and hydrolyzes almost all clinically used β-lactam antibiotics.
Bo Ma, Chao Fang, Linshan Lu, Mingzhi Wang, X. Xue, Ying Zhou, Mingkai Li, Yue Hu, Xiaoxing Luo, Z. Hou   +9 more
semanticscholar   +1 more source

Metallo-β-Lactamase Inhibitor Phosphonamidate Monoesters

ACS Omega, 2022
Being the second leading cause of death and the leading cause of disability-adjusted life years worldwide, infectious diseases remain—contrary to earlier predictions—a major consideration for the public health of the 21st century.
Katarzyna Palica, M. Voráčová, Susann Skagseth, Anna Andersson Rasmussen, L. Allander, M. Hubert, Linus Sandegren, Hanna-Kirstirep Schrøder Leiros, Hanna Andersson, M. Erdélyi   +9 more
semanticscholar   +1 more source

\u3cem\u3eArabidopsis thaliana\u3c/em\u3e GLX2-1 Contains a Dinuclear Metal Binding Site, but Is Not a Glyoxalase 2 [PDF]

, 2009
In an effort to probe the structure and function of a predicted mitochondrial glyoxalase 2, GLX2-1, from Arabidopsis thaliana, GLX2-1 was cloned, overexpressed, purified and characterized using metal analyses, kinetics, and UV–visible, EPR, and 1H-NMR ...
Bennett, Brian, Crowder, Michael W., Limphong, Pattraranee, Makaroff, Christopher A.   +3 more
core   +2 more sources

Molecular heterogeneity ofbla_VIM-2-containing integrons fromPseudomonas aeruginosaplasmids encoding the VIM-2 metallo-β-lactamase [PDF]

FEMS Microbiology Letters, 2001
A bla(VIM-2) metallo-beta-lactamase determinant, identical to that previously identified in Pseudomonas aeruginosa COL-1 isolate from a French hospital, was detected on a 28-kb plasmid carried by a nosocomial isolate of P. aeruginosa from Verona, Italy.
PALLECCHI L., RICCIO M. L., DOCQUIER J. D., FONTANA R., ROSSOLINI G. M.   +4 more
openaire   +4 more sources

Structural Basis of Metallo-β-lactamase Inhibition by N-Sulfamoylpyrrole-2-carboxylates

ACS Infectious Diseases, 2021
Metallo-β-lactamases (MBLs) can efficiently catalyze the hydrolysis of all classes of β-lactam antibiotics except monobactams. While serine-β-lactamase (SBL) inhibitors (e.g., clavulanic acid, avibactam) are established for clinical use, no such MBL ...
Alistair J. M. Farley, Yuri Ermolovich, Karina Calvopiña, P. Rabe, Tharindi D Panduwawala, J. Brem, F. Björkling, C. Schofield   +7 more
semanticscholar   +1 more source

Genetic Features Leading to Reduced Susceptibility to Aztreonam-Avibactam among Metallo-β-Lactamase-Producing Escherichia coli Isolates

Antimicrobial Agents and Chemotherapy, 2020
Metallo-β-lactamase (MBL)-producing Escherichia coli isolates resistant to the newly developed β-lactam/β-lactamase inhibitor drug combination aztreonam-avibactam (ATM-AVI) have been reported.
Mustafa Sadek, M. Juhas, L. Poirel, P. Nordmann   +3 more
semanticscholar   +1 more source