Results 21 to 30 of about 838,128 (221)

Presence of different beta-lactamase classes among clinical isolates of Pseudomonas aeruginosa expressing AmpC beta-lactamase enzyme

Journal of Infection in Developing Countries, 2010
Introduction: Infections caused by Pseudomonas aeruginosa are difficult to treat as the majority of isolates exhibit varying degrees of beta-lactamase mediated resistance to most of the beta-lactam antibiotics.
Supriya Upadhyay, Malay Ranjan Sen, Amitabha Bhattacharjee   +2 more
doaj   +1 more source

The Mechanisms of Catalysis by Metallo β-Lactamases [PDF]

, 2008
Class B β-lactamases or metallo-β-lactamases (MBLs) require zinc ions to catalyse the hydrolysis of β-lactam antibiotics such as penicillins, cephalosporins, carbapenems, and cephamycins.
Michael I. Page, Page, Michael I., Badarau, Adriana, Adriana Badarau   +3 more
core   +3 more sources

Table_5_Increased zinc levels facilitate phenotypic detection of ceftazidime-avibactam resistance in metallo-β-lactamase-producing Gram-negative bacteria.docx

, 2022
Ceftazidime-avibactam is one of the last resort antimicrobial agents for the treatment of carbapenem-resistant, Gram-negative bacteria. Metallo-β-lactamase-producing bacteria are considered to be ceftazidime-avibactam resistant. Here, we evaluated a semi-
Niels Pfennigwerth (5244080), Andreas Hiergeist (3470183), Tamara Rügamer (14155239), Axel Hamprecht (605845), Yvonne Pfeifer (457305), Sören G. Gatermann (12050073), André Gessner (821452), Michaela Simon (6587036), Roman G. Gerlach (7388399), Agnes Schröder (458932), Jonathan Jantsch (458934)   +10 more
core   +1 more source

Metallo-Beta-Lactamases: NDM

Journal of Education, Health and Sport, 2019
Leis Kamil, Mazur Ewelina, Szyperski Paweł, Kaczor Patryk, Kolan Michalina, Wiśniewski Bartłomiej, Jabłońska Magdalena, Kulczyńska Aleksandra, Baska Aleksandra, Kazik Jakub, Bojczuk Daria, Grzelakowska Klaudyna, Kałużny Krystian, Gałązka Przemysław. Metallo-Beta-Lactamases: NDM. Journal of Education, Health and Sport. 2019;9(6):27-40.
Leis, Kamil, Mazur, Ewelina, Szyperski, Paweł, Kaczor, Patryk, Kolan, Michalina, Malinowski, Bartłomiej, Jabłońska, Magdalena, Kulczyńska, Aleksandra, Baska, Aleksandra, Kazik, Jakub, Bojczuk, Daria, Grzelakowska, Klaudyna, Kałużny, Krystian, Gałązka, Przemysław   +13 more
openaire   +7 more sources

Table_3_Increased zinc levels facilitate phenotypic detection of ceftazidime-avibactam resistance in metallo-β-lactamase-producing Gram-negative bacteria.docx

, 2022
Ceftazidime-avibactam is one of the last resort antimicrobial agents for the treatment of carbapenem-resistant, Gram-negative bacteria. Metallo-β-lactamase-producing bacteria are considered to be ceftazidime-avibactam resistant. Here, we evaluated a semi-
Niels Pfennigwerth (5244080), Andreas Hiergeist (3470183), Tamara Rügamer (14155239), Axel Hamprecht (605845), Yvonne Pfeifer (457305), Sören G. Gatermann (12050073), André Gessner (821452), Michaela Simon (6587036), Roman G. Gerlach (7388399), Agnes Schröder (458932), Jonathan Jantsch (458934)   +10 more
core   +1 more source

Antibacterial activity of Syzygium aromaticum (clove) against uropathogens producing ESBL, MBL, and AmpC beta-lactamase: Are we close to getting a new antibacterial agent?

Journal of Family Medicine and Primary Care, 2020
Introduction: The present study was done to access the antibacterial activity of clove (Syzygium aromaticum) against extended-spectrum beta-lactamase (ESBL), metallo-beta-lactamase (MBL), and AmpC beta-lactamase-producing gram-negative bacteria causing ...
Sameer S Faujdar, Dakshina Bisht, Amisha Sharma   +2 more
doaj   +1 more source

Immobilization of IMP-1 metallo-beta-lactamase on Fe3O4@SiO2 as nanobiocatalyst for degradation of beta-lactam antibiotics in wastewater

Water Science and Technology, 2022
Residues of antibiotics in water resources and wastewater have been significant environmental and public health problems. The current study developed a high-efficiency enzymatic nanobiocatalyst for the degradation of beta-lactam antibiotics.
Mohammad javad Shokoohizadeh, Ali Almasi, Farahnaz Karami, Seyyed Alireza Mousavi, Reza Khodarahmi   +4 more
doaj   +1 more source

Table_1_Increased zinc levels facilitate phenotypic detection of ceftazidime-avibactam resistance in metallo-β-lactamase-producing Gram-negative bacteria.docx

, 2022
Ceftazidime-avibactam is one of the last resort antimicrobial agents for the treatment of carbapenem-resistant, Gram-negative bacteria. Metallo-β-lactamase-producing bacteria are considered to be ceftazidime-avibactam resistant. Here, we evaluated a semi-
Niels Pfennigwerth (5244080), Andreas Hiergeist (3470183), Tamara Rügamer (14155239), Axel Hamprecht (605845), Yvonne Pfeifer (457305), Sören G. Gatermann (12050073), André Gessner (821452), Michaela Simon (6587036), Roman G. Gerlach (7388399), Agnes Schröder (458932), Jonathan Jantsch (458934)   +10 more
core   +1 more source

A multiscale approach to predict the binding mode of metallo beta‐lactamase inhibitors [PDF]

Proteins: Structure, Function, and Bioinformatics, 2021
Abstract Antibiotic resistance is a major threat to global public health. β‐lactamases, which catalyze breakdown of β‐lactam antibiotics, are a principal cause. Metallo β‐lactamases (MBLs) represent a particular challenge because they hydrolyze almost all β‐lactams and to date no MBL inhibitor has been approved for clinical use ...
Silvia Gervasoni, James Spencer, Philip Hinchliffe, Alessandro Pedretti, Franco Vairoletti, Graciela Mahler, Adrian J. Mulholland   +6 more
openaire   +3 more sources

Influence of disk preparation on detection of metallo-beta-lactamase-producing isolates by the combined disk assay [PDF]

, 2007
The combined disk assay has been used for detection of metallo-beta-lactamase-producing isolates. We have observed that the size of inhibition zones produced by many beta-lactam/metallo-beta-lactamase inhibitor (IMBL) combinations may differ depending on
Picao, Renata C. [UNIFESP], Nicoletti, Adriana G. [UNIFESP], Campana, Eloiza H. [UNIFESP], Andrade, Soraya S. [UNIFESP], Gales, Ana C. [UNIFESP], Pignatari, Antonio C. C. [UNIFESP]   +5 more
core   +1 more source