Results 31 to 40 of about 838,128 (221)

Table_4_Increased zinc levels facilitate phenotypic detection of ceftazidime-avibactam resistance in metallo-β-lactamase-producing Gram-negative bacteria.docx

, 2022
Ceftazidime-avibactam is one of the last resort antimicrobial agents for the treatment of carbapenem-resistant, Gram-negative bacteria. Metallo-β-lactamase-producing bacteria are considered to be ceftazidime-avibactam resistant. Here, we evaluated a semi-
Niels Pfennigwerth (5244080), Andreas Hiergeist (3470183), Tamara Rügamer (14155239), Axel Hamprecht (605845), Yvonne Pfeifer (457305), Sören G. Gatermann (12050073), André Gessner (821452), Michaela Simon (6587036), Roman G. Gerlach (7388399), Agnes Schröder (458932), Jonathan Jantsch (458934)   +10 more
core   +1 more source

Investigation of Metallo-beta-lactamase Genes (L1 and NDM1) in Isolates of Stenotrophomonas maltophilia

Acta Medica Iranica, 2022
Stenotrophomonas maltophilia is resistant to a wide range of antibiotics. This study aimed to investigate the beta-lactamase, ESBL, and MBL enzymes and also L1and NDM1 genes in isolates of Stenotrophomonas maltophilia.
Rabeeh Izadi Amoli, Jamileh Nowroozi
doaj   +1 more source

Table_2_Increased zinc levels facilitate phenotypic detection of ceftazidime-avibactam resistance in metallo-β-lactamase-producing Gram-negative bacteria.docx

, 2022
Ceftazidime-avibactam is one of the last resort antimicrobial agents for the treatment of carbapenem-resistant, Gram-negative bacteria. Metallo-β-lactamase-producing bacteria are considered to be ceftazidime-avibactam resistant. Here, we evaluated a semi-
Niels Pfennigwerth (5244080), Andreas Hiergeist (3470183), Tamara Rügamer (14155239), Axel Hamprecht (605845), Yvonne Pfeifer (457305), Sören G. Gatermann (12050073), André Gessner (821452), Michaela Simon (6587036), Roman G. Gerlach (7388399), Agnes Schröder (458932), Jonathan Jantsch (458934)   +10 more
core   +1 more source

Antibacterial potential of neem (Azadirachta indica) against uropathogens producing beta-lactamase enzymes: A clue to future antibacterial agent?

Biomedical and Biotechnology Research Journal, 2020
Background: Emergence of drug resistance in Gram-negative bacilli due to production of extended-spectrum beta-lactamases (ESBL), metallo-beta-lactamases (MBL), and AmpC beta-lactamase is very common nowadays; therefore, we are left with less choice for ...
Sameer Singh Faujdar, Dakshina Bisht, Amisha Sharma   +2 more
doaj   +1 more source

Metallo-beta-lactamase inhibitor phosphonamidate monoesters

, 2021
NMR raw data (FIDs) and processed spectra of the synthesized ...
Palica, Katarzyna, Voracova, Manuela, Skagseth, Susann, Andersson Rasmussen, Anna, Schroder Leiros, Hanna-Kirsti, Andersson, Hanna, Erdelyi, Mate   +6 more
openaire   +2 more sources

Purification and biochemical characterization of IMP-13 metallo-beta-lactamase. [PDF]

, 2011
The IMP-13 metallo-beta-lactamase was overproduced in Escherichia coli BL21(DE3) and purified by chromatography. Analysis of kinetic parameters revealed some notable differences with other IMP-type enzymes, noteworthily a higher catalytic efficiency ...
Radice, M., Gisela Santella, Gutkind, G., Gutkind G, Gabriel Gutkind, Gutkind, Gabriel Osvaldo, Marcela Radice, Radice M., Gian Maria Rossolini, Santella, G., Docquier, Jean-Denis, Rossolini, G. M., Santella G, DOCQUIER, JEAN DENIS, Santella, Gisela, ROSSOLINI, GIAN MARIA, Radice, Marcela Alejandra, Jean-Denis Docquier   +17 more
core   +1 more source

Biofilm and metallo beta-lactamase production among the strains of Pseudomonas aeruginosa and Acinetobacter spp. at a Tertiary Care Hospital in Kathmandu, Nepal

Annals of Clinical Microbiology and Antimicrobials, 2017
Introduction Pseudomonas aeruginosa and Acinetobacter spp. are found to be associated with biofilm and metallo-β-lactamase production and are the common causes of serious infections mainly in hospitalized patients. So, the main aims of this study were to
Bandana Baniya, Narayan Dutt Pant, Sanjeev Neupane, Saroj Khatiwada, Uday Narayan Yadav, Nisha Bhandari, Rama Khadka, Sabita Bhatta, Raina Chaudhary   +8 more
doaj   +1 more source

Detecção de metalo-beta-lactamase em Pseudomonas aeruginosa isoladas de pacientes hospitalizados em Goiânia, Estado de Goiás Detection of metallo-beta-lactamase in Pseudomonas aeruginosa isolated from hospitalized patients in Goiânia, State of Goiás

Revista da Sociedade Brasileira de Medicina Tropical, 2009
Pseudomonas aeruginosa é uma bactéria frequentemente isolada no ambiente hospitalar. Este estudo teve como objetivo avaliar o perfil de suscetibilidade de Pseudomonas aeruginosa previamente isoladas de pacientes internados em um hospital de Goiânia ...
Diana Christina Pereira Santos Gonçalves, Ana Beatriz Mori Lima, Lara Stefania Netto de Oliveira Leão, José Rodrigues do Carmo Filho, Fabiana Cristina Pimenta, José Daniel Gonçalves Vieira   +5 more
doaj   +1 more source

Structural compatibility between β‐lactams and substrate binding pockets of IMP‐1 and NDM‐1 determines the substrate spectrum

Bulletin of the Korean Chemical Society, EarlyView.
Chemical structures of three β‐lactam classes and the substrate‐binding pockets (SBPs) of B1 metallo‐β‐lactamases (MBLs) were compared. Structural compatibility between β‐lactams and MBL SBPs correlates with enzymatic activity, providing insights into the substrate spectrum of MBLs and β‐lactam resistance.
Kiwoong Kwak, Jiwon Yun, Donghyun Lee, Byung‐Jin Lee, Juyeon Lim, Jung Hun Lee, Sang Hee Lee, Soon Young Shin, Lin‐Woo Kang   +8 more
wiley   +1 more source

Prevalence of metallo-β-lactamase-encoding genes among carbapenem-resistant Pseudomonas aeruginosa strains isolated from burn patients in Iran

, 2018
Carbapenem-resistant Pseudomonas aeruginosa (CRPA) has been considered a major cause of infection and mortality in burn patients, especially in developing countries such as Iran. One of the most common mechanisms of carbapenem resistance is production of
Mohammad Emaneini (3220215), Fereshteh Jabalameli (3220212), Reza Beigverdi (3220209), Elahe Taki (6071255)   +3 more
core   +1 more source