Results 91 to 100 of about 811,638 (168)

Metallo beta lactamase producing Pseudomonas aeruginosa and Acinetobacter baumannii

Indian Journal of Medical Microbiology, 2011
This study aims in identifying MBLs particularly Zn requiring Molecular Class B enzymes produced by Pseudomonas aeruginosa and Acinetobacter baumannii .The resistance by these organisms are in a rise against all antibiotics including carbapenems and no prescribed CLSI guidelines is available for detecting them.
John, S, Balagurunathan, R
openaire   +2 more sources

Prevalence of metallo-β-lactamase-encoding genes among carbapenem-resistant Pseudomonas aeruginosa strains isolated from burn patients in Iran

Revista da Sociedade Brasileira de Medicina Tropical
Carbapenem-resistant Pseudomonas aeruginosa (CRPA) has been considered a major cause of infection and mortality in burn patients, especially in developing countries such as Iran. One of the most common mechanisms of carbapenem resistance is production of
Fereshteh Jabalameli, Elahe Taki, Mohammad Emaneini, Reza Beigverdi   +3 more
doaj   +1 more source

Structure based drug design: the discovery of novel inhibitors active against New Delhi Metallo-β-lactamase-1

, 2017
Background. The emergence of bacterial strains resistant to available antibiotic armamentarium is nowadays a pressing issue in clinical therapy. Among the several mechanisms of bacterial resistance, the rapid evolution and spread of carbapenemases, β ...
Cross, Simon, Perilli, Mariagrazia, Celenza, Giuseppe, Cendron, Laura, TONDI, Donatella, Bellio, Pierangelo, SPYRAKIS, FRANCESCA, Marcoccia, Francesca   +7 more
core  

BLOODSTREAM INFECTIONS CAUSED BY CARBAPENEM-RESISTANT ENTEROBACTERALES: IMPACT OF CEFTAZIDIME-AVIBACTAM ANTIBIOTIC THERAPY ON LETHALITY

Brazilian Journal of Infectious Diseases
Bloodstream infections (BSIs) caused by carbapenem-resistant Enterobacterales (CRE) are associated with high morbidity and mortality and represent a global public health threat.
Lorena Galvão de Araújo, Fabianna Márcia Maranhão Bahia, Edilane Gouveia Voss, Joice Neves Reis Pedreira   +3 more
doaj   +1 more source

blaIMP and blaVIM mediated carbapenem resistance in Pseudomonas and Acinetobacter species in India

Journal of Infection in Developing Countries, 2012
Introduction: The emergence and rapid spread of blaIMP and blaVIM metallo-beta-lactamase (MBL) producing Gram-negative bacteria causing nosocomial infections are of concern worldwide due to limited treatment options.
M Shanthi Amudhan, Uma Sekar, Arunagiri Kamalanathan, Sekar Balaraman   +3 more
doaj   +1 more source

Ceftibuten stability to active-site serine and metallo-ß-lactamases

, 2001
Ceftibuten is an oral third-generation cephalosporin active against a wide range of bacteria and shows an improved stability to hydrolysis by several beta -lactamases because of the carboxyethilidine moiety at position 7 of the beta -acyl side chain. The
Perilli, Mariagrazia, Andrea Mancinelli, Caravelli, Berardo, Amicosante, Gianfranco, Giovanni Gizzi, Tavio Perez, Maria Del Mar, Bruno Bianchi, Segatore, Bernardetta, Nicola Franceschini, Mancinelli, Andrea, Gizzi, Giovanni, Gianfranco Amicosante, Mariagrazia Perilli, Bianchi, Bruno, Bernardetta Segatore, Domenico Setacci, Franceschini, Nicola, Berardo Caravelli, Maria del Mar Tavio-Perez, Setacci, Domenico, Tavio-Perez, Maria Del Mar   +20 more
core   +1 more source

A STUDY OF METALLO-BETA-LACTATAMASE PRODUCING PSEUDOMONAS AERUGINOSA IN CLINICAL SAMPLES OF S.S.G. HOSPITAL

National Journal of Medical Research, 2011
Introduction: Pseudomonas spp. is common pathogen causing nosocomial infection. Acquired drug resistance is frequent in nosocomial isolates of Pseudomonas spp. Acquired metallo-β-lactamases (MBL) in pseudomonas spp.
Mehul S Chaudhari, Tanuja B Javadekar, Govind Ninama, Govind Ninama, Jivraj Damor   +4 more
doaj  

Epidemiology of carbapenemase-producing Enterobacteriaceae in a pediatric hospital in a country with high endemicity

Journal of Infection and Public Health, 2019
Background: Little is known about epidemiology of carbapenemase-producing Enterobacteriaceae (CPE) in children. Aim of this study was to describe CPE epidemiology in a tertiary care pediatric hospital in Italy that admits patients coming from geographic ...
Elio Castagnola, Paola Tatarelli, Alessio Mesini, Ivana Baldelli, Daniela La Masa, Roberto Biassoni, Roberto Bandettini   +6 more
doaj   +1 more source

Metallo-beta-lactamases: novel weaponry for antibiotic resistance in bacteria

, 2006
Metallo-beta-lactamases are broad-spectrum zinc enzymes, able to inactivate most clinically useful beta-lactam antibiotics. Their structural and functional diversity has thus far limited the understanding of their catalytic mechanism, therefore thwarting
Crowder, MW, Spencer, J, Vila, AJ
core   +1 more source

Comparative Study of Biofilm and Non-Biofilm Producing Klebsiella pneumoniae with Special Reference to Metallo-Beta-Lactamase Production

Journal of Pure and Applied Microbiology
Klebsiella pneumoniae is one of the most common bacteria among all biofilm-producing as well as the beta-lactamase producing strains, which is responsible for multi-drug resistance.
Prajakta S. Pawar, Satyajeet K. Pawar, Satish R. Patil, Harsha V. Patil, Priyanka M. Mane   +4 more
doaj   +1 more source