Molecular Docking and In Vitro Studies of Ochratoxin A (OTA) Biodetoxification Testing Three Endopeptidases [PDF]
Molecules, 2023 Ochratoxin A (OTA) is considered one of the main mycotoxins responsible for health problems and considerable economic losses in the feed industry.
Pablo César Orozco-Cortés +4 more
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Membrane metalloendopeptidase (MME) is positively correlated with systemic lupus erythematosus and may inhibit the occurrence of breast cancer. [PDF]
PLoS ONE, 2023 BackgroundPatients with systemic lupus erythematosus (SLE) have a lower risk of breast cancer (BRCA) than the general population. In this study, we explored the underlying molecular mechanism that is dysregulated in both diseases.MethodsWeighted gene ...
Jiatong Ding +6 more
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Production and application of peptidyl-lys metalloendopeptidase: advances, challenges, and future perspectives [PDF]
Applied Microbiology and BiotechnologyPeptidyl-lys metalloendopeptidases (PKMs) are enzymes that selectively cleave peptide bonds at the N-terminus of lysine residues present in the P1′ position, making them valuable tools in proteomics.
Uzair Ahmed +2 more
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Association of MME gene polymorphisms with susceptibility to Alzheimer's disease in an Iranian population [PDF]
HeliyonBackground: the MME gene encodes a membrane metalloendopeptidase, known as neprilysin (NEP). There are no reports on the potential implications of MME gene polymorphisms on the risk of Alzheimer's disease (AD) in the Iranian population. In this study, we
Fereshteh Khalili-Moghadam +4 more
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Interactions between Helcococcus kunzii and Staphylococcus aureus: How a commensal bacterium modulates the virulence and metabolism of a pathogen in a chronic wound in vitro model [PDF]
BMC MicrobiologyBackground Staphylococcus aureus is the predominant pathogen isolated in diabetic foot infections. Recently, the skin commensal bacterium, Helcococcus kunzii, was found to modulate the virulence of this pathogen in an in vivo model.
Benjamin A. R. N Durand +6 more
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Influences of Trypsin Pretreatment on the Structures, Composition, and Functional Characteristics of Skin Gelatin of Tilapia, Grass Carp, and Sea Perch [PDF]
Marine Drugs, 2023 Fish skin gelatin is an important functional product in the food, cosmetics, and biomedicine industries, and establishing a green and effective fish skin gelatin extraction method is an effective way to obtain high-quality gelatin and improve its ...
Qiufeng Ruan +7 more
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Multi-omics study of the anti-colorectal cancer mechanisms of formononetin in Hedysari Radix [PDF]
Frontiers in PharmacologyBackgroundHedysari Radix (HR), commonly known as Hong-Qi in Chinese, is a traditional Chinese herbal medicine recognized for possessing anti-inflammatory and anti-tumor properties.
Jun Rao +14 more
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Silent hyperlipidaemia modulated vascular endothelial markers [PDF]
Pharmacia, 2021 The aetiology of ischemic heart diseases is mainly based on atherosclerosis of coronary artery. Inflammation and oxidative reactions are initiating and aggravating the illness resulting in pathological remodelling of vasculaturze at site of injury ...
Marwan Merkhan +5 more
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Integration of single‐cell and bulk RNA sequencing unravels metalloendopeptidase+ neutrophils as key inflammatory drivers in abdominal aortic aneurysm [PDF]
Clinical and Translational MedicineLushun Yuan +4 more
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Assessment of Serum Metalloendopeptidase level in Patients with Double Diabetes
مجله كليه طب الكندي, 2023 Background: Double diabetes is the term used to describe situations in which a patient exhibits characteristics that are a combination of type 1 and type 2 Diabetes Mellitus. Metalloendopeptidase or Neprilysin is membrane-bound metallopeptidase.
Hussein Jawad Hassan +2 more
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