Results 41 to 50 of about 7,597 (252)

Metalloprotease meprin beta in rat kidney: glomerular localization and differential expression in glomerulonephritis. [PDF]

PLoS ONE, 2008
Meprin (EC 3.4.24.18) is an oligomeric metalloendopeptidase found in microvillar membranes of kidney proximal tubular epithelial cells. Here, we present the first report on the expression of meprin beta in rat glomerular epithelial cells and suggest a ...
Beatrice Oneda, Nadège Lods, Daniel Lottaz, Christoph Becker-Pauly, Walter Stöcker, Jeffrey Pippin, Maya Huguenin, Daniel Ambort, Hans-Peter Marti, Erwin E Sterchi   +9 more
doaj   +1 more source

Subtractive genomic analysis for computational identification of putative immunogenic targets against clinical Enterobacter cloacae complex.

PLoS ONE, 2022
BackgroundEnterobacter is a major nosocomial genus of Enterobacteriaceae responsible for a variety of nosocomial infections, particularly in prolonged hospitalized patients in the intensive care units.
Negin Bolourchi, Sepideh Fereshteh, Narjes Noori Goodarzi, Farzad Badmasti   +3 more
doaj   +2 more sources

A new brain metalloendopeptidase which degrades the Alzheimer ß-amyloid 1-40 peptide producing soluble fragments without neurotoxic effects

Brazilian Journal of Medical and Biological Research, 1997
A new metalloendopeptidase was purified to apparent homogeneity from a homogenate of normal human brain using successive steps of chromatography on DEAE-Trisacryl, hydroxylapatite and Sephacryl S-200.
K.M. Carvalho, M.S.F. França, G.C. Camarão, A.F. Ruchon   +3 more
doaj   +1 more source

Polymorphisms of the matrix metalloproteinase genes are associated with essential hypertension in a Caucasian population of Central Russia

Scientific Reports, 2021
This study aimed to determine possible association of eight polymorphisms of seven MMP genes with essential hypertension (EH) in a Caucasian population of Central Russia.
Maria Moskalenko, Irina Ponomarenko, Evgeny Reshetnikov, Volodymyr Dvornyk, Mikhail Churnosov   +4 more
doaj   +1 more source

Comparison of Stemness and Gene Expression between Gingiva and Dental Follicles in Children [PDF]

, 2016
published_or_final_versio
Choi, HJ, Jeon, M, Jung, HS, Kang, CM, Kim, SO, Lee, JH   +5 more
core   +4 more sources

Extracellular matrix and dermal nerve growth factor dysregulation in prurigo nodularis compared to atopic dermatitis

Frontiers in Medicine, 2022
Prurigo nodularis (PN) is a chronic, pruritic, inflammatory skin disease characterized by hyperkeratotic nodules on the trunk and extremities. While there is growing research on the immunological basis of PN, the neuropathic and structural components of ...
Junwen Deng, Varsha Parthasarathy, Melika Marani, Zachary Bordeaux, Kevin Lee, Chi Trinh, Hannah L. Cornman, Anusha Kambala, Thomas Pritchard, Shihua Chen, Nishadh Sutaria, Olusola O. Oladipo, Madan M. Kwatra, Martin P. Alphonse, Shawn G. Kwatra   +14 more
doaj   +1 more source

Acute cocaine treatment increases thimet oligopeptidase in the striatum of rat brain [PDF]

, 2012
Many studies indicate that thimet oligopeptidase (EC3.4.24.15; TOP) can be implicated in the metabolism of bioactive peptides, including dynorphin 1-8, alpha-neoendorphin, beta-neoendorphin and GnRH.
Andersen, Monica Levy, Bicocchi, Eliane S., Chagas, Jair Ribeiro, Dalio, Fernanda Montiel, Ferro, Emer Suavinho, Freua, Rodrigo, Gesteira, Tarsis Ferreira, Machado, Mauricio Ferreira Marcondes, Nader, Helena Bonciani, Oliveira, Vitor, Perry, Juliana Cini, Toledo, Claudio A. B., Tufik, Sergio, Visniauskas, Bruna   +13 more
core   +1 more source

Mycobacterium leprae downregulates the expression of PHEX in Schwann cells and osteoblasts

Memorias do Instituto Oswaldo Cruz, 2010
Neuropathy and bone deformities, lifelong sequelae of leprosy that persist after treatment, result in significant impairment to patients and compromise their social rehabilitation.
Sandra R Boiça Silva, Antônio J Tempone, Tatiana P Silva, Maria Renata SN Costa, Geraldo MB Pereira, Flávio A Lara, Maria Cristina V Pessolani, Danuza Esquenazi   +7 more
doaj   +1 more source

A nonsense mutation in MME gene associates with autosomal recessive late‐onset Charcot–Marie–Tooth disease

Molecular Genetics & Genomic Medicine, 2022
Background The genetic cause for the majority of patients with late‐onset axonal form of neuropathies have remained unknown. In this study we aimed to identify the causal mutation in a family with multiple affected individuals manifesting a range of ...
Zeinab Jamiri, Rana Khosravi, Mohammad Mehdi Heidari, Ebrahim Kiani, Javad Gharechahi   +4 more
doaj   +1 more source

Role of CD10 as a Prognostic Marker in Invasive Breast Carcinoma [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Stromal markers have been proved as important markers in assessing the prognosis of invasive breast cancer. Cluster of Differentiation (CD)10 is a cell surface enzyme with metalloendopeptidase activity which is expressed in stroma of ...
Subitha Kandamuthan, Renu Thambi
doaj   +1 more source