Results 11 to 20 of about 4,754 (192)

Assessment of Serum Metalloendopeptidase level in Patients with Double Diabetes [PDF]

open access: yesمجله كليه طب الكندي, 2023
Background: Double diabetes is the term used to describe situations in which a patient exhibits characteristics that are a combination of type 1 and type 2 Diabetes Mellitus. Metalloendopeptidase or Neprilysin is membrane-bound metallopeptidase.
Hussein Jawad Hassan   +2 more
doaj   +2 more sources

Secretion of Metalloendopeptidase 24.15 (EC 3.4.24.15) [PDF]

open access: yesDNA and Cell Biology, 1999
The metalloendopeptidase EP24.15 (EC3.4.24.15) is a neuropeptide-metabolizing enzyme present in neural and endocrine tissues, presumably functioning extracellularly. Because the majority of the EP24.15 activity is identified in the soluble fraction of cellular homogenates, suggesting that the enzyme is primarily an intracellular protein, we addressed ...
Ferro, E. S.   +3 more
openaire   +4 more sources

A liver metalloendopeptidase which degrades the circulating hypotensive peptide hormones bradykinin and atrial natriuretic peptide [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 1999
A new metalloendopeptidase was purified to apparent homogeneity from a homogenate of normal human liver using successive steps of chromatography on DEAE-cellulose, hydroxyapatite and Sephacryl S-200.
Carvalho K.M.   +5 more
doaj   +3 more sources

Silent hyperlipidaemia modulated vascular endothelial markers [PDF]

open access: yesPharmacia, 2021
The aetiology of ischemic heart diseases is mainly based on atherosclerosis of coronary artery. Inflammation and oxidative reactions are initiating and aggravating the illness resulting in pathological remodelling of vasculaturze at site of injury ...
Marwan Merkhan   +5 more
doaj   +3 more sources

A novel metalloendopeptidase from rat bone.

open access: yes, 1990
A soluble metalloendopeptidase was extracted from rat bone. This enzyme can be considered novel, since it is different from all other soluble metalloendopeptidases reported in the literature.
Bollen, Anne-Marie
core   +7 more sources

The astacin family of metalloendopeptidases [PDF]

open access: yesProtein Science, 1995
AbstractThe astacin family of metalloendopeptidases was recognized as a novel family of proteases in the 1990s. The crayfish enzyme astacin was the first characterized and is one of the smallest members of the family. More than 20 members of the family have now been identified.
J S, Bond, R J, Beynon
openaire   +2 more sources

Families of metalloendopeptidases and their relationships [PDF]

open access: yesFEBS Letters, 1992
Crystal structures available for four metalloendopeptidases have revealed zinc ligands for these enzymes. New sequence information has made it possible to compare the primary structures of the zinc‐binding site in metalloendopeptidases. A scheme based on the zinc‐binding site is proposed to classify metalloendopeptidases into five distinct families ...
Jiang, Weiping, Bond, Judith S.
openaire   +2 more sources

Safety evaluation of the food enzyme bacillolysin from the non‐genetically modified Bacillus amyloliquefaciens strain HPN 131

open access: yesEFSA Journal, 2023
The food enzyme bacillolysin (EC 3.4.24.28) is produced with the non‐genetically modified Bacillus amyloliquefaciens strain HPN 131 by ENMEX SA de CV.
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP)   +23 more
doaj   +1 more source

Membrane metalloendopeptidase (MME) is positively correlated with systemic lupus erythematosus and may inhibit the occurrence of breast cancer.

open access: yesPLoS ONE, 2023
BackgroundPatients with systemic lupus erythematosus (SLE) have a lower risk of breast cancer (BRCA) than the general population. In this study, we explored the underlying molecular mechanism that is dysregulated in both diseases.MethodsWeighted gene ...
Jiatong Ding   +6 more
doaj   +2 more sources

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