Results 11 to 20 of about 4,754 (192)
Assessment of Serum Metalloendopeptidase level in Patients with Double Diabetes [PDF]
Background: Double diabetes is the term used to describe situations in which a patient exhibits characteristics that are a combination of type 1 and type 2 Diabetes Mellitus. Metalloendopeptidase or Neprilysin is membrane-bound metallopeptidase.
Hussein Jawad Hassan +2 more
doaj +2 more sources
Secretion of Metalloendopeptidase 24.15 (EC 3.4.24.15) [PDF]
The metalloendopeptidase EP24.15 (EC3.4.24.15) is a neuropeptide-metabolizing enzyme present in neural and endocrine tissues, presumably functioning extracellularly. Because the majority of the EP24.15 activity is identified in the soluble fraction of cellular homogenates, suggesting that the enzyme is primarily an intracellular protein, we addressed ...
Ferro, E. S. +3 more
openaire +4 more sources
A liver metalloendopeptidase which degrades the circulating hypotensive peptide hormones bradykinin and atrial natriuretic peptide [PDF]
A new metalloendopeptidase was purified to apparent homogeneity from a homogenate of normal human liver using successive steps of chromatography on DEAE-cellulose, hydroxyapatite and Sephacryl S-200.
Carvalho K.M. +5 more
doaj +3 more sources
Silent hyperlipidaemia modulated vascular endothelial markers [PDF]
The aetiology of ischemic heart diseases is mainly based on atherosclerosis of coronary artery. Inflammation and oxidative reactions are initiating and aggravating the illness resulting in pathological remodelling of vasculaturze at site of injury ...
Marwan Merkhan +5 more
doaj +3 more sources
A novel metalloendopeptidase from rat bone.
A soluble metalloendopeptidase was extracted from rat bone. This enzyme can be considered novel, since it is different from all other soluble metalloendopeptidases reported in the literature.
Bollen, Anne-Marie
core +7 more sources
Integration of single‐cell and bulk RNA sequencing unravels metalloendopeptidase+ neutrophils as key inflammatory drivers in abdominal aortic aneurysm [PDF]
Lushun Yuan +4 more
doaj +2 more sources
The astacin family of metalloendopeptidases [PDF]
AbstractThe astacin family of metalloendopeptidases was recognized as a novel family of proteases in the 1990s. The crayfish enzyme astacin was the first characterized and is one of the smallest members of the family. More than 20 members of the family have now been identified.
J S, Bond, R J, Beynon
openaire +2 more sources
Families of metalloendopeptidases and their relationships [PDF]
Crystal structures available for four metalloendopeptidases have revealed zinc ligands for these enzymes. New sequence information has made it possible to compare the primary structures of the zinc‐binding site in metalloendopeptidases. A scheme based on the zinc‐binding site is proposed to classify metalloendopeptidases into five distinct families ...
Jiang, Weiping, Bond, Judith S.
openaire +2 more sources
The food enzyme bacillolysin (EC 3.4.24.28) is produced with the non‐genetically modified Bacillus amyloliquefaciens strain HPN 131 by ENMEX SA de CV.
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP) +23 more
doaj +1 more source
BackgroundPatients with systemic lupus erythematosus (SLE) have a lower risk of breast cancer (BRCA) than the general population. In this study, we explored the underlying molecular mechanism that is dysregulated in both diseases.MethodsWeighted gene ...
Jiatong Ding +6 more
doaj +2 more sources

