Results 31 to 40 of about 6,440 (201)
Spatial clustering and common regulatory elements correlate with coordinated gene expression [PDF]
, 2019 Many cellular responses to surrounding cues require temporally concerted transcriptional regulation of multiple genes. In prokaryotic cells, a single-input-module motif with one transcription factor regulating multiple target genes can generate ...
Bai, Fan +6 more
core +3 more sources
Soluble Metalloendopeptidases and Neuroendocrine Signaling [PDF]
Endocrine Reviews, 2002 Peptidases play a vital and often highly specific role in the physiological and pathological generation and termination of peptide hormone signals. The thermolysin-like family of metalloendopeptidases involved in the extracellular processing of neuroendocrine and cardiovascular peptides are of particular significance, reflecting both their specificity ...
Corie N, Shrimpton +2 more
openaire +2 more sources
Mycobacterium leprae downregulates the expression of PHEX in Schwann cells and osteoblasts
Memorias do Instituto Oswaldo Cruz, 2010 Neuropathy and bone deformities, lifelong sequelae of leprosy that persist after treatment, result in significant impairment to patients and compromise their social rehabilitation.
Sandra R Boiça Silva +7 more
doaj +1 more source
Molecular Genetics & Genomic Medicine, 2022 Background The genetic cause for the majority of patients with late‐onset axonal form of neuropathies have remained unknown. In this study we aimed to identify the causal mutation in a family with multiple affected individuals manifesting a range of ...
Zeinab Jamiri +4 more
doaj +1 more source
Midgut proteome of an argasid tick, Ornithodoros erraticus: a comparison between unfed and engorged females [PDF]
, 2007 16 páginas, 5 figuras y 2 tablas. -- Agradecimientos: Asistencia técnica de Rocío Vizcaíno Marín y María González Sánchez, del Instituto de Recursos Naturales y Agrobiología de Salamanca (IRNASA-CSIC) y de la Dra.
Oleaga, Ana +3 more
core +1 more source
The Journal of Clinical Investigation, 2022 Mitochondrial stress triggers a response in the cell’s mitochondria and nucleus, but how these stress responses are coordinated in vivo is poorly understood.
Mario K. Shammas +16 more
doaj +1 more source
The stromal processing peptidase of chloroplasts is essential in Arabidopsis, with knockout mutations causing embryo arrest after the 16-cell stage. [PDF]
PLoS ONE, 2011 Stromal processing peptidase (SPP) is a metalloendopeptidase located in the stroma of chloroplasts, and it is responsible for the cleavage of transit peptides from preproteins upon their import into the organelle. Two independent mutant Arabidopsis lines
Raphael Trösch, Paul Jarvis
doaj +1 more source
Revista Brasileira de Zootecnia, 2020 A selection of commercially available antibodies, targeted against markers employed in studies of mammary gland biology, was tested to determine their reactivity in goat mammary tissue and the derived tissue cultures.
Sonja Prpar Mihevc +2 more
doaj +1 more source
Post-translational processing targets functionally diverse proteins in Mycoplasma hyopneumoniae [PDF]
, 2016 © 2016 The Authors. Mycoplasma hyopneumoniae is a genome-reduced, cell wall-less, bacterial pathogen with a predicted coding capacity of less than 700 proteins and is one of the smallest self-replicating pathogens. The cell surface of M. hyopneumoniae is
Berry, IJ +10 more
core +2 more sources
Families of metalloendopeptidases and their relationships [PDF]
FEBS Letters, 1992 Crystal structures available for four metalloendopeptidases have revealed zinc ligands for these enzymes. New sequence information has made it possible to compare the primary structures of the zinc‐binding site in metalloendopeptidases. A scheme based on the zinc‐binding site is proposed to classify metalloendopeptidases into five distinct families ...
Jiang, Weiping, Bond, Judith S.
openaire +2 more sources