Results 71 to 80 of about 6,440 (201)

A liver metalloendopeptidase which degrades the circulating hypotensive peptide hormones bradykinin and atrial natriuretic peptide

Brazilian Journal of Medical and Biological Research, 1999
A new metalloendopeptidase was purified to apparent homogeneity from a homogenate of normal human liver using successive steps of chromatography on DEAE-cellulose, hydroxyapatite and Sephacryl S-200.
Carvalho K.M., Nava R.A., França M.S.F., Medeiros M.A.S., Camarão G.C., Juliano L.   +5 more
doaj  

Validation of Messenger Ribonucleic Acid Markers Differentiating Among Human Acute Respiratory Distress Syndrome Subgroups in an Ovine Model of Acute Respiratory Distress Syndrome Phenotypes

Frontiers in Medicine, 2022
BackgroundThe discovery of biological subphenotypes in acute respiratory distress syndrome (ARDS) might offer a new approach to ARDS in general and possibly targeted treatment, but little is known about the underlying biology yet.
Karin Wildi, Karin Wildi, Karin Wildi, Kieran Hyslop, Jonathan Millar, Jonathan Millar, Jonathan Millar, Samantha Livingstone, Samantha Livingstone, Margaret R. Passmore, Margaret R. Passmore, Mahé Bouquet, Mahé Bouquet, Emily Wilson, Emily Wilson, Gianluigi LiBassi, Gianluigi LiBassi, John F. Fraser, John F. Fraser, Jacky Y. Suen, Jacky Y. Suen   +20 more
doaj   +1 more source

Aberrant gene expression in mucosa adjacent to tumor reveals a molecular crosstalk in colon cancer [PDF]

, 2015
Background: A colorectal tumor is not an isolated entity growing in a restricted location of the body. The patient's gut environment constitutes the framework where the tumor evolves and this relationship promotes and includes a complex and tight ...
Berenguer, Antoni, Cordero Romera, David, Crous Bou, Marta, Garcia i Molleví, David, Guinó, Elisabet, Moreno Aguado, Víctor, Oca Burguete, Javier de, Paré Brunet, Laia, Rodríguez Moranta, Francisco, Salazar Soler, Ramón, Sanjuan, Xavier, Santos, Cristina, Sanz Pamplona, Rebeca, Solé Acha, Xavier   +13 more
core   +2 more sources

Multiomics Reveals the Molecular Mechanism of Collagen Synthesis by Hydrolyzed Collagen Supplementation of Large Yellow Croaker (Larimichthys crocea)

Aquaculture Nutrition, Volume 2026, Issue 1, 2026.
This study investigated the effects of dietary hydrolyzed collagen supplementation on muscle quality and its underlying molecular mechanisms in large yellow croaker (Larimichthys crocea) (initial weight: 332.27 ± 3.79 g) over a 128‐day feeding trial.
Fangle Tong, Xuexue Zhang, Lina Zhang, Xiaocheng Deng, Yalan Zhang, Shi Wang, Zehong Wei, Chuanpeng Zhou   +7 more
wiley   +1 more source

Finished Genome of the Fungal Wheat Pathogen Mycosphaerella graminicola Reveals Dispensome Structure, Chromosome Plasticity, and Stealth Pathogenesis [PDF]

, 2011
The plant-pathogenic fungus Mycosphaerella graminicola (asexual stage: Septoria tritici) causes septoria tritici blotch, a disease that greatly reduces the yield and quality of wheat.
Goodwin, S.B., M'Barek, S., Ben, Dhillon, B., Wittenberg, A.H.J., Crane, C.F., Hane, J.K., Foster, A.J., Lee, T.A.J., van der, Grimwood, J., Aerts, A., Antoniw, J., Bailey, A., Bluhm, B., Bowler, J., Bristow, J., Burgt, A., van der, Canto-Canché, B., Churchill, A.C.L., Conde-Ferràez, L., Cools, H.J., Coutinho, P.M., Csukai, M., Dehal, P., Wit, P.J.G.M., de, Donzelli, B., Geest, H.C., van de, Ham, R.C.H.J., van, Hammond-Kosack, K.E., Henrissat, B., Kilian, A., Kobayashi, A.K., Koopmann, E., Kourmpetis, Y., Kuzniar, A., Lindquist, E., Lombard, V., Maliepaard, C.A., Martins, N., Mehrabi, A., Nap, J.P.H., Ponomarenko, A., Rudd, J.J., Salamov, A., Schmutz, J., Schouten, H.J., Shapiro, H., Stergiopoulos, I., Torriani, S.F.F., Tu, H., Vries, R.P., de, Waalwijk, C., Ware, S.B., Wiebenga, A., Zwiers, L.H., Oliver, R.P., Grigoriev, I.V., Kema, G.H.J.   +56 more
core   +3 more sources

Nicotinamide Riboside Improves Mitochondrial Function and Oocyte Maturation in Aged Mice: A Multitarget Mechanistic Study Using Network Pharmacology and Molecular Simulations

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Mitochondrial dysfunction plays a critical role in ovarian aging and the associated decline in female fertility. Nicotinamide riboside (NR), a vitamin B3 derivative and dietary NAD+ precursor, has shown antiaging potential, yet its molecular mechanisms in ovarian function are not fully understood.
Ningyu Sun, Xiang Cheng, Lu Lu, Wuwen Zhang, Kai Li, Yuanyuan Chen, Yun Li, Chunling Liu, Qinhua Zhang, Ping Yin, Anupama Bose   +10 more
wiley   +1 more source

Safety evaluation of the food enzyme bacillolysin from the non‐genetically modified Bacillus amyloliquefaciens strain NZYM‐NB

EFSA Journal
The food enzyme bacillolysin (EC 3.4.24.28) is produced with the non‐genetically modified Bacillus amyloliquefaciens strain NZYM‐NB by Novozymes A/S.
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Claude Lambré, José Manuel Barat Baviera, Claudia Bolognesi, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger‐Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Lieve Herman, Yrjö Roos, Magdalena Andryszkiewicz, Daniele Cavanna, Simone Lunardi, Eleonora Marini, Francesco Pesce, Andrew Chesson   +24 more
doaj   +1 more source

The astacin family of metalloendopeptidases.

Journal of Biological Chemistry, 1991
Molecular cloning of a human intestinal brush border metalloendopeptidase (N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase, PPH) and a mouse kidney brush border metalloendopeptidase (meprin A) has revealed 82% identity in the NH2-terminal amino acid sequences (198 residues) of the mature enzymes.
E, Dumermuth, E E, Sterchi, W P, Jiang, R L, Wolz, J S, Bond, A V, Flannery, R J, Beynon   +6 more
openaire   +2 more sources

Integrated Multiomics Elucidates Molecular Mechanisms of Bisphenol A in Exacerbating Crohn’s Disease

Mediators of Inflammation, Volume 2026, Issue 1, 2026.
Background Bisphenol A (BPA), a widespread environmental endocrine‐disrupting chemical, has been associated with the development and progression of Crohn’s disease (CD), yet its precise molecular mechanisms remain unclear. We aimed to systematically elucidate the potential molecular mechanisms by which BPA exacerbates CD and to identify key biomarkers ...
Liangliang Dai, Chenjie Qiu, Veedamali S. Subramanian   +2 more
wiley   +1 more source

Safety evaluation of the food enzyme bacillolysin from the non‐genetically modified Bacillus amyloliquefaciens strain AE‐NP

EFSA Journal
The food enzyme bacillolysin (EC 3.4.24.28) is produced with the non‐genetically modified Bacillus amyloliquefaciens strain AE‐NP by Amano Enzyme Inc. The production strain meets the requirements for the qualified presumption of safety (QPS) approach to ...
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Claude Lambré, José Manuel Barat Baviera, Claudia Bolognesi, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Inger‐Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Yrjö Roos, Magdalena Andryszkiewicz, Daniele Cavanna, Simone Lunardi, Francesco Pesce, Andrew Chesson   +22 more
doaj   +1 more source