Associations of Neprilysin and Its Coding Gene Variation With Hypertension in Chinese Adults
ABSTRACT Neprilysin (NEP) degrades several vasoactive peptides and may contribute to blood pressure maintenance. This study aims to examine the associations between serum NEP levels and variants at its coding gene and hypertension in a general Chinese population.
Junting Hu +14 more
wiley +1 more source
Chloroplast Proteins without Cleavable Transit Peptides [PDF]
Most chloroplast proteins (cp proteins) are nucleus-encoded, synthesized on cytosolic ribosomes as precursor proteins containing a presequence (cTP), and post-translationally imported via the Tic/Toc complex into the organelle, where the cTP is removed ...
Armbruster, Ute +11 more
core +1 more source
Differential Properties of Venom Peptides and Proteins in Solitary vs. Social Hunting Wasps
The primary functions of venoms from solitary and social wasps are different. Whereas most solitary wasps sting their prey to paralyze and preserve it, without killing, as the provisions for their progeny, social wasps usually sting to defend their ...
Si Hyeock Lee +2 more
doaj +1 more source
Transcriptional factor regulation network and competitive endogenous RNA (ceRNA) network determining response of esophageal squamous cell carcinomas to neoadjuvant chemoradiotherapy [PDF]
Background Neoadjuvant chemoradiotherapy (nCRT) followed by surgery benefits survival for patients with esophageal squamous cell carcinomas (ESCC) compared with surgery alone, but the clinical outcomes of nCRT are heterogeneous.
Mingrui Shao, Wenya Li
doaj +2 more sources
Evidence for systems-level molecular mechanisms of tumorigenesis [PDF]
Background: Cancer arises from the consecutive acquisition of genetic alterations. Increasing evidence suggests that as a consequence of these alterations, molecular interactions are reprogrammed in the context of highly connected and regulated cellular ...
David Montaner +8 more
core +2 more sources
The Genetic Basis of Color Polymorphism in the Orb‐Web Spider Gasteracantha cancriformis
This study investigates the genetic basis of coloration in the polymorphic spider Gasteracantha cancriformis using RNA‐seq data from different female color morphs. We assembled a reference transcriptome and identified differentially expressed genes associated with known pigmentation pathways, including carotenoids, melanin, ommochromes, and pteridines.
Paula Torres‐Quintero +3 more
wiley +1 more source
Natural and laboratory mutations in kuzbanian are associated with zinc stress phenotypes in Drosophila melanogaster [PDF]
Organisms must cope with altered environmental conditions such as high concentrations of heavy metals. Stress response to heavy metals is mediated by the metal-responsive transcription factor 1 (MTF-1), which is conserved from Drosophila to humans. MTF-1
Barrón, Maite G. +5 more
core +1 more source
A new metalloendopeptidase was purified to apparent homogeneity from a homogenate of normal human liver using successive steps of chromatography on DEAE-cellulose, hydroxyapatite and Sephacryl S-200.
Carvalho K.M. +5 more
doaj
BackgroundThe discovery of biological subphenotypes in acute respiratory distress syndrome (ARDS) might offer a new approach to ARDS in general and possibly targeted treatment, but little is known about the underlying biology yet.
Karin Wildi +20 more
doaj +1 more source
Virulence and Antimicrobial Resistance in Enterococci Isolated from Urinary Tract Infections [PDF]
Purpose: Urinary tract infection (UTI) is the most common nosocomial infection among hospitalized patients. Meanwhile, most frequent infections involving enterococci affect the urinary tract.
Ahad Bazmani +6 more
core +1 more source

