Results 91 to 100 of about 4,754 (192)

Evaluation of metalloendopeptidase Lys-N protease performance under different sample handling conditions.

, 2010
Trypsin, the most widely used enzyme in proteomics, has a few caveats as it does not perform well under certain harsh sample handling conditions and creates relatively short peptides less amenable to, for instance, electron transfer dissociation.
Heck, AJ, Mohammed, S, Mohammed, Shabaz, Shabaz Mohammed, Albert J. R. Heck, Nadia Taouatas, Taouatas, N   +6 more
core   +1 more source

Inhibition of bone resorption in vitro by human enkephalinase (EC 3.4.24.11), a neutral metalloendopeptidase

, 1992
Bone metabolism is regulated by a wide variety of both circulating and locally produced peptides. The activity of such agents must be regulated, and one potential regulating mechanism is the inactivation of these peptides by locally produced proteolytic ...
Monique Deschodt‐Lanckman, D'Souza, Sharyn S.M., Ibbotson, Kenneth K.J., Deschodt Lanckman, Monique, Sharyn M. D'souza, Thierry E. Appelboom, Kenneth J. Ibbotson, Appelboom, Thierry   +7 more
core   +1 more source

Interactions between Helcococcus kunzii and Staphylococcus aureus: How a commensal bacterium modulates the virulence and metabolism of a pathogen in a chronic wound in vitro model

BMC Microbiology
Background Staphylococcus aureus is the predominant pathogen isolated in diabetic foot infections. Recently, the skin commensal bacterium, Helcococcus kunzii, was found to modulate the virulence of this pathogen in an in vivo model.
Benjamin A. R. N Durand, Riham Daher, Lucia Grenga, Madjid Morsli, Jean Armengaud, Jean-Philippe Lavigne, Catherine Dunyach-Remy   +6 more
doaj   +1 more source

Identification of Membrane-bound Variant of Metalloendopeptidase Neurolysin (EC 3.4.24.16) as the Non-angiotensin Type 1 (Non-AT1), Non-AT2 Angiotensin Binding Site

, 2012
Recently, we discovered a novel non-AT1, non-AT2 angiotensin binding site in rodent and human brain membranes, which is distinctly different from angiotensin receptors and key proteases processing angiotensins.
Bader, Michael, Speth, R.C., Emanuel Escher, Michael Bader, Wangler, Naomi J, Kira L. Santos, Escher, E., Vardan T. Karamyan, Santos, Kira L, Naomi J. Wangler, Ines Schadock, Robert C. Speth, Santos, K.L., Schadock, I., Wangler, N.J., Schadock, Ines, Speth, Robert C, Fred K. Hagen, Hagen, Fred K, Karamyan, Vardan T, Karamyan, V.T., Hagen, F.K., Bader, M., Escher, Emanuel   +23 more
core   +1 more source

Multi-omics study of the anti-colorectal cancer mechanisms of formononetin in Hedysari Radix

Frontiers in Pharmacology
BackgroundHedysari Radix (HR), commonly known as Hong-Qi in Chinese, is a traditional Chinese herbal medicine recognized for possessing anti-inflammatory and anti-tumor properties.
Jun Rao, Jun Rao, Jun Rao, Xing Wang, Tanxiu Chen, Mingzi Mo, Conglong Xu, So-Yi Chang, So-Yi Chang, Ssu-Wei Hsu, Ssu-Wei Hsu, Xiaoqun Han, Ching-Hsien Chen, Ching-Hsien Chen, Zhi Zheng   +14 more
doaj   +1 more source

In-depth quantitative cardiac proteomics combining electron transfer dissociation and the metalloendopeptidase Lys-N with the SILAC mouse.

, 2011
In quantitative proteomics stable isotope labeling has progressed from cultured cells toward the total incorporation of labeled atoms or amino acids into whole multicellular organisms.
Delanghe, B, Heck, AJR, Mohammed, S, Mohammed, Shabaz, Low, T., Low, TY, Heck, A. J. R., Zanivan, S, van Veen, TA, Van Veen, TAB, Heck, AJ, Scholten, A., Scholten, A, Low, T. Y., Heck, A., Zanivan, S., van Veen, T. A. B., Mohammed, S., Delanghe, B., van Veen, T.   +19 more
core   +1 more source

Membrane Metalloendopeptidase (MME) Suppresses Metastasis of Esophageal Squamous Cell Carcinoma (ESCC) by Inhibiting FAK-RhoA Signaling Axis

, 2019
Esophageal squamous cell carcinoma (ESCC) is a typical neoplastic disease and a frequent cause of death in China. Although great achievements have been made in diagnostic strategies and combination therapies in recent years, the prognosis of ESCC is ...
Guan, X, Li, M, Ling Wang, Xu Zhang, Zhang, X, Tingting Zeng, Wang, L, Mengqing Li, Li, Y, Zhan, Y, Zeng, T, Xin-Yuan Guan, Yuting Zhan, Yan Li   +13 more
core   +1 more source

A non-synonymous SNP within membrane metalloendopeptidase-like 1 (MMEL1) is associated with multiple sclerosis

, 2010
Several single-nucleotide polymorphism (SNP) genome-wide association studies (GWASs) have been completed in multiple sclerosis (MS). Follow-up studies of the variants with the most promising rankings, especially when supplemented by informed candidate ...
Robertson NP, Dudbridge F, Sexton D, Compston A, Kemppinen A, Oksenberg JR, Hafler DA, Sawcer S, Haines J, Baker A, Guerini FR, Pericak-Vance MA, Zuvich R, Barcellos LF, Ban M, McCauley JL, Lechner-Scott J, Bergamaschi L, Ivinson AJ, Cox M, D'Alfonso S, Wason J, Hauser SL, De Jager PL   +23 more
core   +2 more sources

Regulating Pathways of Bacillus pumilus Adamalysin-like Metalloendopeptidase Expression. [PDF]

Int J Mol Sci, 2023
Rudakova NL, Sabirova AR, Khasanov DI, Danilova IV, Sharipova MR.   +4 more
europepmc   +1 more source

Late-Onset Charcot-Marie-Tooth Type 2 Patient: MME Gene Mutation. [PDF]

Ann Indian Acad Neurol
Işık K, Altıner K, Boz BD, Demirel EA, Atasoy HT.   +4 more
europepmc   +1 more source