Results 61 to 70 of about 4,257 (183)

The Extracellular Vesicles of the Helminth Pathogen, Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis [PDF]

open access: yes, 2015
Extracellular vesicles (EVs) released by parasites have important roles in establishing and maintaining infection. Analysis of the soluble and vesicular secretions of adult Fasciola hepatica has established a definitive characterization of the total ...
Bernal, Dolores   +11 more
core   +1 more source

Multiomics Reveals the Molecular Mechanism of Collagen Synthesis by Hydrolyzed Collagen Supplementation of Large Yellow Croaker (Larimichthys crocea)

open access: yesAquaculture Nutrition, Volume 2026, Issue 1, 2026.
This study investigated the effects of dietary hydrolyzed collagen supplementation on muscle quality and its underlying molecular mechanisms in large yellow croaker (Larimichthys crocea) (initial weight: 332.27 ± 3.79 g) over a 128‐day feeding trial.
Fangle Tong   +7 more
wiley   +1 more source

X‐Linked Hypophosphatemia Caused by a New Partial Insertion of LINE‐1 in the PHEX Gene

open access: yesHuman Mutation, Volume 2026, Issue 1, 2026.
X‐linked hypophosphatemia (XLH), primarily caused by mutations of the PHEX gene, is the most common cause of genetic rickets. Pediatric cases of XLH typically present with elevated levels of serum fibroblast growth factor 23 (FGF23), hypophosphatemia, rickets, and impaired growth.
Dongmei Li   +6 more
wiley   +1 more source

The genome of Strongyloides spp. gives insights into protein families with a putative role in nematode parasitism [PDF]

open access: yes, 2016
SUMMARYParasitic nematodes are important and abundant parasites adapted to live a parasitic lifestyle, with these adaptations all aimed at facilitating their survival and reproduction in their hosts.
Hunt, Vicky L   +3 more
core   +2 more sources

Single‐Cell Transcriptomic Profiling and Machine Learning Integration Unveil Stromal Cell Heterogeneity in Endometriosis

open access: yesHuman Mutation, Volume 2026, Issue 1, 2026.
Background Endometriosis (EMs) affects approximately 10% of reproductive‐age women worldwide, yet its pathogenesis remains incompletely understood. Abnormal cell differentiation and somatic mutations in the ectopic endometrial microenvironment play critical roles in disease progression and treatment response heterogeneity.
Huipeng Zhang, Yuli Luo, Hao Chi
wiley   +1 more source

Nicotinamide Riboside Improves Mitochondrial Function and Oocyte Maturation in Aged Mice: A Multitarget Mechanistic Study Using Network Pharmacology and Molecular Simulations

open access: yesJournal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Mitochondrial dysfunction plays a critical role in ovarian aging and the associated decline in female fertility. Nicotinamide riboside (NR), a vitamin B3 derivative and dietary NAD+ precursor, has shown antiaging potential, yet its molecular mechanisms in ovarian function are not fully understood.
Ningyu Sun   +10 more
wiley   +1 more source

Functional characterization of the Mycobacterium tuberculosis zinc metallopeptidase Zmp1 and identification of potential substrates [PDF]

open access: yes, 2017
Zinc metallopeptidases of bacterial pathogens are widely distributed virulence factors and represent promising pharmacological targets. In this work, we have characterized Zmp1, a zinc metallopeptidase identified as a virulence factor of Mycobacterium ...
Amstutz, Beat   +11 more
core  

The genome and developmental transcriptome of the strongylid nematode Haemonchus contortus [PDF]

open access: yes, 2013
Background: The barber's pole worm, Haemonchus contortus, is one of the most economically important parasites of small ruminants worldwide. Although this parasite can be controlled using anthelmintic drugs, resistance against most drugs in common use has
Antoshechkin, Igor A.   +19 more
core   +2 more sources

Enzyme kinetics of protease from Hypsizygus ulmarius [PDF]

open access: yes, 2014
Enzyme kinetics of protease activity from ext. of edible mushroom, Hypsizygus ulmarius were carried out. The optimum pH and temp. for protease activity were found to be at 10 and 40°C resp. The pH and temp.
Premkumari, B., Shivashankar, M.
core   +1 more source

Genome of the human hookworm Necator americanus [PDF]

open access: yes, 2014
The hookworm Necator americanus is the predominant soil-transmitted human parasite. Adult worms feed on blood in the small intestine, causing iron-deficiency anemia, malnutrition, growth and development stunting in children, and severe morbidity and ...
Gao, Xin   +3 more
core  

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