Results 1 to 10 of about 196 (135)
Biotechnology Reports (Amsterdam, Netherlands), 2018 Enzymes from the thermolysin family are crucial factors in the pathogenesis of several diseases caused by bacteria and are potential targets for therapeutic interventions.
Rosa Maria Chura Chambi +2 more
exaly +3 more sources
The Effect of High Pressure on Thermolysin [PDF]
FEBS Journal, 1997 The effects of high pressure on thermolysin activity and spectroscopic properties were studied. Thermolysin showed distinct pressure‐induced activation with a maximum observed at 200–250 MPa for a dipeptide amide substrate and at 100–120 MPa for a heptapeptide substrate.
Shigeru Kunugi, C Balny
exaly +3 more sources
Radiofrequency remote control of thermolysin activity [PDF]
Scientific Reports, 2021 The majority of biological processes are regulated by enzymes, precise control over specific enzymes could create the potential for controlling cellular processes remotely.
Christian B. Collins +2 more
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Angiotensin-converting enzyme inhibitor activity of peptides derived from Kacang goat skin collagen through thermolysin hydrolysis [PDF]
Veterinary World, 2021 Background and Aim: Angiotensin-converting enzyme (ACE) is one of the inhibitory enzymes isolated from animals for the treatment of hypertension.
Arby'in Pratiwi +6 more
doaj +1 more source
Molecules, 2023 β-casein, a protein in milk and dairy products, has two main variant forms termed as A1 and A2. A1 β-casein may have adverse effects on humans. The fact that there is only one amino acid variation at the 67th position between A1 and A2 β-casein makes it ...
Zeyang Liu +4 more
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Casein Proteolysis in Bioactive Peptide Production: Optimal Operating Parameters [PDF]
Техника и технология пищевых производств, 2020 Introduction. Public health is gradually deteriorating as a result of unhealthy lifestyle and diet, which triggers allergic reaction to certain foods.
Milentyeva Irina S. +2 more
doaj +1 more source
Hayati Journal of Biosciences, 2023 Proteolytic enzymes are widely used to produce protein hydrolysates that contain bioactive peptides. Some of bioactive peptides are known inhibit the angiotensin-I-converting enzyme (ACE, EC 3.4.15.1) and act as human antihypertensive.
Dininurilmi Putri Suleman +2 more
doaj +1 more source
Bacterial Zinc Metalloenzyme Inhibitors: Recent Advances and Future Perspectives
Molecules, 2023 Human deaths caused by Gram-negative bacteria keep rising due to the multidrug resistance (MDR) phenomenon. Therefore, it is a priority to develop novel antibiotics with different mechanisms of action.
Riccardo Di Leo +3 more
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Evaluation of new antihypertensive drugs designed in silico using Thermolysin as a target
Saudi Pharmaceutical Journal, 2020 The search for new therapies for the treatment of Arterial hypertension is a major concern in the scientific community. Here, we employ a computational biochemistry protocol to evaluate the performance of six compounds (Lig783, Lig1022, Lig1392, Lig2177,
Desmond MacLeod-Carey +3 more
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Isolation and identification of angiotensin I-converting enzyme inhibitory peptides derived from thermolysin-injected beef [PDF]
Asian-Australasian Journal of Animal Sciences, 2019 Objective This study identified angiotensin I-converting enzyme (ACE) inhibitory peptides in beef M. longissimus injected with thermolysin (80 ppm) and stored for 3 days at 5°C. Methods Crude peptides (molecular weight
Juhui Choe +5 more
doaj +1 more source