Results 81 to 90 of about 23,484 (216)
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts [PDF]
, 2015 Despite the astonishing breadth of enzymes in nature, no enzymes are known for many of the valuable catalytic transformations discovered by chemists. Recent work in enzyme design and evolution, however, gives us good reason to think that this will change.
Arnold, Frances H. +1 more
core +1 more source
Asymmetric Reduction of Unactivated Alkenes
Chemistry – A European Journal, EarlyView.Unactivated alkenes rank among the most inert functional groups in synthesis and their selective reduction remains challenging. This Review charts the evolution from classical metal‐catalyzed hydrogenation to radical hydrogen atom transfer (HAT) and emerging biocatalytic concepts, highlighting how complementary mechanistic strategies, including the ...
Nico D. Fessner +3 more
wiley +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2018 The inhibition of the δ-class carbonic anhydrase (CAs, EC 4.2.1.1) from the diatom Thalassiosira weissflogii, TweCAδ, was investigated using a panel of 36 mono- and di-thiocarbamates chemotypes that have recently been shown to inhibit mammalian and ...
Silvia Bua +6 more
doaj +1 more source
Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.ABSTRACT Animals with seasonal reproductive cycles, as the Roe deer (Capreolus capreolus), have developed mechanisms to synchronize reproduction with the environmental cycle in order to optimize reproductive success through melatonin. Angiogenesis and oxidative stress are key processes in spermatogenesis, contributing to testicular remodeling and ...
Ilaria Troisio +7 more
wiley +1 more source
PhotoMat, EarlyView.This paper presents a comprehensive overview of recent advancements in Joule‐heating synthesis of photo and electrocatalysts, emphasizing its benefits and applications. The objective is to offer an effective strategy for enhancing the diversity and performance of catalytic materials.
Jiaqi Li +4 more
wiley +1 more source
Regulation of Matrix Metalloproteinases by Wine-Derived Compounds: Implications for Cancer Therapy
BiomoleculesCancer remains a prevalent global health concern, with key factors such as diet, environment, and genetics playing significant roles in its progression.
Md. Towhedul Islam +2 more
doaj +1 more source
Frontiers in Chemistry, 2019 Biological enzymes are macromolecular catalysts that catalyze the biochemical reactions of the natural systems. Although each enzyme performs a particular function, however, holds several drawbacks, which limits its utilization in broad-spectrum ...
Sanjay Singh
doaj +1 more source
Molecular structure and nickel‐binding capacity of Proteus mirabilis UreE
Acta Crystallographica Section D, EarlyView.This study presents a 2.0 Å resolution crystal structure and determined the nickel‐binding capacity of the P. mirabilis nickel chaperone UreE. UreE is essential for the delivery of nickel to the metalloenzyme urease, which is key for the ability of P. mirabilis to cause urinary‐tract infections.UreE is a nickel chaperone that is required for the safe ...
Jiayi Pan +4 more
wiley +1 more source
Molecules, 2019 Nature has tailored a wide range of metalloenzymes that play a vast array of functions in all living organisms and from which their survival and evolution depends on.
Henrique S. Fernandes +3 more
doaj +1 more source
Design of Heteronuclear Metalloenzymes [PDF]
, 2016 Heteronuclear metalloenzymes catalyze some of the most fundamentally interesting and practically useful reactions in nature. However, the presence of two or more metal ions in close proximity in these enzymes makes them more difficult to prepare and study than homonuclear metalloenzymes.
A, Bhagi-Damodaran +5 more
openaire +2 more sources